Preparation method of microchip for teaching

Abstract

The invention discloses a preparation method of a microchip for teaching. The preparation method comprises the followings steps: 1) designing the position of a pipeline in a culture vessel, sculpturing a raised pipeline model at the corresponding pipeline by using a hot melt adhesive, waiting until the hot melt adhesive is coagulated; 2) placing the culture vessel on the surface of an iron box, and placing a magnet at an outlet of the pipeline to achieve a template with a three-dimensional space structure; 3) preparing PDMS rubber according to the ratio (1:10) of a monomer to a curing agent, carrying out mixing, pouring the mixture into the culture vessel, and drying the mixture; 4) stripping the completely dried PDMS rubber from the culture vessel, and removing the magnet; and 5) sealing the surface of the PDMS rubber in the step 4 by using the other PDMS lower negative film to obtain a chip body. The method is rapid and convenient in preparation and very convenient to mold and strip, liquid storage tanks with different thicknesses are obtained through the standard magnet, and through simple preparation, boring contents such as the Lambert-Beer law and the thin-layer chromatography theory can be favorably understood by students by practices.

Description

technical field [0001] The invention relates to the technical field of analytical chemistry teaching equipment, in particular to a method for preparing a microchip for chemistry teaching. Background technique [0002] This technology belongs to the intersection field of miniaturized chemical reaction device and microfluidic chip technology. Its main idea is to use the technology of microfluidic chip to make new miniaturized analytical chemistry teaching equipment. Manz A et al. The concept of miniaturized total analysis system (μ-TAS) was proposed for the first time. Among them, the microfluidic chip integrates analytical chemistry, micro-electro-mechanical system (mi-cro-electro-mechanical system, MEMS), computer, materials science, biomedicine and other multidisciplinary fields, and integrates various functions of the chemical laboratory such as sample pre-processing. Processing, sample injection, separation and detection, etc., are integrated into a credit card-sized chi...

AI Technical Summary

Problems solved by technology

However, miniaturized devices generally still need supporting facilities such as water and electricity, which cannot be brought into the classroom for experiments. At the same time, the equipment needs to be specially made, so the price is also relatively expensive, and teachers and students cannot realize the self-design of the reaction device.

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