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Repair effect of traditional Chinese medicine component-radix morindae officinalis polysaccharide for injury to male reproductive system

A technology of male reproduction and Morinda officinalis, applied in the repairing effect of Morinda officinalis polysaccharides on male reproductive system damage, and in the field of traditional Chinese medicine ingredients, it can solve problems such as liver and kidney toxicity, complex components of Morinda officinalis, and improve sexual performance, Effects of improving fertility and increasing testosterone levels

Inactive Publication Date: 2017-05-17
FUJIAN MEDICAL UNIV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the defects that the existing Chinese herbal medicine Morinda officinalis has obvious repairing effect on the damage of the male reproductive system, but the ingredients in Morinda officinalis are complicated, and the direct edible crude drug has certain liver and kidney toxicity defects, and provides a Repairing effect of Morinda officinalis polysaccharide, a traditional Chinese medicine ingredient, on male reproductive system damage

Method used

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  • Repair effect of traditional Chinese medicine component-radix morindae officinalis polysaccharide for injury to male reproductive system
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  • Repair effect of traditional Chinese medicine component-radix morindae officinalis polysaccharide for injury to male reproductive system

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Embodiment

[0025] One, the extraction method of Morinda officinalis polysaccharide, comprises the following steps:

[0026] (1) Extract Morinda officinalis powder with 3 times the mass of 95% ethanol in a boiling water bath for 2 hours, and repeat once to remove fat-soluble components and oligosaccharides;

[0027] (2) The dregs are naturally volatilized until there is no alcohol smell, extracted with 6 times the mass of double distilled water in a boiling water bath for 2 hours, and repeated twice;

[0028] (3) Combine the liquid medicines and concentrate them with a rotary evaporator until the specific gravity reaches 1.2 g / mL; add absolute ethanol to make the volume fraction of ethanol reach 60%, put in a refrigerator at 4°C overnight, collect the precipitate, and obtain Morinda officinalis crude sugar;

[0029] (4) Add an equal amount of water to dissolve Morinda officinalis coarse sugar, add 1 / 3 volume of sevag reagent (chloroform: n-butanol = 1:4), place in a separatory funnel, sha...

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Abstract

The invention discloses use of radix morindae officinalis polysaccharide in preparation of medicines or health foods for preventing and treating male reproductive system diseases. The radix morindae officinalis polysaccharide has an average molecular weight of (1.0-1.5)*10<4>, and the dosage of the radix morindae officinalis polysaccharide is 200-300mg kg<-1>; after being directly used for preparing the medicines or the health foods for preventing and treating the male reproductive system diseases, the radix morindae officinalis polysaccharide can repair the injury to a male reproductive system, promote spermatogenic function, improve sexual behavior ability, enhance reproductive capacity and increase the testosterone level in a body, so that the technical problem that radix morindae officinalis has toxicity for liver and kidney when being directly eaten is avoided.

Description

technical field [0001] The invention relates to the technical field of polysaccharide extraction and application, in particular to the repairing effect of a traditional Chinese medicine component Morinda officinalis polysaccharide on male reproductive system damage. Background technique [0002] Due to the influence of factors such as environmental pollution and increased life pressure, people's fertility is gradually decreasing, and infertility has become a worldwide medical and sociological problem. According to the World Health Organization estimates, there are 60-80 million infertile couples in the world. close. Clinically, clomiphene and indomethacin are commonly used to treat various oligozoospermia and asthenozoospermia, which have certain curative effects, but they all have different degrees of toxic and side effects. Clomiphene can cause side effects such as changes in weight and libido, mild depression, nausea, dizziness, visual disturbances, gastrointestinal rea...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61P9/14A61P15/08C08B37/00
CPCA61K31/715A61K9/14A61K36/746C08B37/0003
Inventor 王玮张丽虹赵小贞
Owner FUJIAN MEDICAL UNIV
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