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Application of traditional Chinese medicine composition with Uraria crinita in preparation of drugs for preventing and treating porcine viral diarrhea

A technology of clary tail grass and a composition, which is applied in the field of traditional Chinese medicine, can solve the problems of strong virulence, environmental pollution, easy repeated infection, etc., and achieves the effects of sufficient sources and excellent bacteriostatic effect.

Inactive Publication Date: 2017-05-31
INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Viral diarrhea vaccines for pigs are divided into strong vaccines and inactivated vaccines. The virulent vaccines are fed to pregnant sows by mixing the intestinal contents and feces of infected pigs on the farm to make them produce antibodies and protect piglets. However, this method does not Eliminate the presence of viruses, which are extremely prone to repeated infections
However, the virulence of the strains of inactivated vaccines is unstable, and there are hidden dangers such as reversion to strong virulence or too weak virulence to form an immune response.
[0004] In addition to vaccination, antibiotics and other drugs can be used to control bacterial infection caused by viral infection in order to prevent pig viral diarrhea, thereby improving the survival rate of pigs, but the abuse of antibiotics will pollute the environment and may even screen The emergence of superbugs makes the prevention and control of the epidemic more difficult. In addition, if not handled properly, the antibiotics remaining in the pork may have adverse effects on the human body, so there is a potential risk for the prevention and treatment of swine viral diarrhea

Method used

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  • Application of traditional Chinese medicine composition with Uraria crinita in preparation of drugs for preventing and treating porcine viral diarrhea
  • Application of traditional Chinese medicine composition with Uraria crinita in preparation of drugs for preventing and treating porcine viral diarrhea
  • Application of traditional Chinese medicine composition with Uraria crinita in preparation of drugs for preventing and treating porcine viral diarrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: prepare Chinese medicine composition with preparation method of the present invention

[0022] Weigh 150g of Timothy, 10g of Astragalus, 10g of Glycyrrhiza radix and 10g of Glycyrrhiza glabra, add 1600ml of ethanol with a volume fraction of 60% and heat and reflux for extraction twice, each time for 40min, filter after alcohol extraction, and concentrate the filtrate to extract Instantly.

Embodiment 2

[0023] Embodiment 2: prepare Chinese medicine composition with preparation method of the present invention

[0024] Weigh 100g of Timothy, 30g of Astragalus, 40g of Glycyrrhiza radix and 40g of Glycyrrhiza glabra, add 630ml of ethanol with a volume fraction of 95% to heat and reflux for extraction twice, each time for 30min, filter after alcohol extraction, and concentrate the filtrate to extract Instantly.

Embodiment 3

[0025] Embodiment 3: prepare Chinese medicine composition with preparation method of the present invention

[0026] Weigh 80g of timothus, 30g of astragalus, 50g of licorice, and 50g of glaucous bean, add 2100ml of ethanol with a volume fraction of 40% and heat and reflux to extract twice, each time for 1h, filter after alcohol extraction, and concentrate the filtrate to extract Instantly.

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Abstract

The invention relates to the field of traditional Chinese medicine and discloses application of a traditional Chinese medicine composition with Uraria crinita in the preparation of drugs for preventing and treating porcine viral diarrhea; the traditional Chinese medicine composition comprises Uraria crinita, root of Mongolian milkvetch, root of ural licorice and Crotalaria zanzibarica, is prepared by ethanol thermal reflux extraction and water decoction and extraction, and may prevent and treat porcine viral diarrhea. The traditional Chinese medicine composition according to the invention has good antiviral effect, the source of active pharmaceutical ingredients is sufficient, and the traditional Chinese medicine composition is widely applicable to the preparation of drugs for treating porcine viral diarrhea in piglets, adult boars and adult sows.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of a traditional Chinese medicine composition containing cattail grass and its application in medicine for suppressing porcine viral diarrhea. Background technique [0002] Porcine viral diarrhea is a relatively common disease in pig herds. Its pathogenic viruses mainly include porcine epidemic diarrhea virus, porcine rotavirus, porcine pseudorabies virus and porcine transmissible gastroenteritis virus. Infection with one of them After one or more cases, symptoms such as watery diarrhea and vomiting often appear in the infected pigs, and the onset is sudden and the transmission is fast. Piglets within one week of age can easily die within 2-7 days after symptoms appear, and the mortality rate can reach 100%. Adult pigs can gradually recover after 3-7 days of diarrhea, but may form a dead pig. Porcine viral diarrhea is a worldwide epidemic, which s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61P1/12A61P31/12
Inventor 袁靖喆戴好富梅文莉王辉
Owner INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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