Pharmaceutical composition for cough and asthma of livestock and poultry and preparation process thereof

A composition and drug technology, which is applied to drug combinations, medical preparations containing active ingredients, and medical raw materials derived from angiosperm subphylum, etc. problem, to achieve the effect of easy mass production, simple preparation method and improved resistance

Inactive Publication Date: 2017-05-31
ZHONGYUEMINAN BEIJING TECH DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine has low bioavailability and slow onset of effect due to large crushed particle size or unreasonable formula, so the effect is not very ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Tinglizi 200g, Morus alba 150g, Perilla 150g, Trichosanthes 100g, Scutellaria baicalensis 100g, Andrographis 100g, Radix isatidis 100g, Golden buckwheat 50g, Puffball 50g.

[0036] The preparation process is as follows: Weigh 9 medicinal materials such as Tinglizi, Morus alba, Perilla, Melonium, Scutellaria, Andrographis, Radix Isatidis, Golden Buckwheat, Puffball, etc., and add 12 times the amount of water to decoct three times. After 1 hour, combine the decoction liquid, filter, let stand overnight, filter the supernatant, concentrate under reduced pressure to a relative density of 1.20-1.27 (50°C), and dry under reduced pressure to form a dry paste. The dry paste is crushed through a 100-mesh sieve, and an appropriate amount of starch is added and mixed to obtain 1000 g of powder.

Embodiment 2

[0038] Tinglizi 250g, Morus alba 200g, Perilla 200g, Trichosanthes 150g, Scutellaria baicalensis 150g, Andrographis 150g, Radix isatidis 150g, Golden buckwheat 100g, Puffball 100g.

[0039] The preparation process is as follows: Weigh Tinglizi, Morus alba, Perilla seed, Gualou, Scutellaria baicalensis, Andrographis paniculata, Radix Isatidis, Golden Buckwheat and Puffball, add 10 times the amount of water and decoct 3 times, 2 hours each time, combine and decoct Boil the liquid, filter, concentrate under reduced pressure to a relative density of 1.15-1.20 (50°C), dry, pulverize, pass through a 100-mesh sieve, add an appropriate amount of dextrin to the dry cream powder, mix evenly, and granulate to obtain 1500 g of granules.

Embodiment 3

[0041] Tinglizi 300g, Morus alba 200g, Perilla 200g, Trichosanthes 100g, Scutellaria baicalensis 100g, Andrographis 100g, Radix isatidis 100g, Golden buckwheat 20g, Puffball 20g.

[0042] The preparation process is as follows: Weigh 9 medicinal materials such as Tinglizi, Morus alba, Perilla, Gualou, Scutellaria, Andrographis, Radix Isatidis, Golden Buckwheat, Puffball, etc., and add 8 times the amount of water to decoct three times. After 3 hours, combine the decoction, filter, mix and concentrate the filtrate to 0.8 times the total amount of the original medicinal materials, add ethanol to make the alcohol content reach 60%, and let it stand for 12 hours. Filtrate, recover ethanol from the filtrate, lower the temperature to below 40°C, adjust the pH value to 5.5-6.5, add water for injection to a total of 1000ml, filter, subpackage, fill with nitrogen, seal, and sterilize to obtain oral liquid.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for cough and asthma of livestock and poultry and a preparation process thereof. The composition is mainly prepared from the following drugs in parts by weight: 15-25 parts of semen lepidii, 10-20 parts of the root bark of white mulberry, 10-20 parts of fructus perillae, 5-15 parts of snakegourd fruit, 5-15 parts of scutellaria baicalensis, 5-15 parts of creat, 5-15 parts of isatis root, 1-10 parts of wild buckwheat and 1-10 parts of puffball. The pharmaceutical composition has the functions of clearing heat and eliminating phlegm, removing heat from lung and relieving asthma, and inducing diuresis to alleviate edema, can effectively control cough and asthma and other respiratory diseases in large scale farming of the livestock and poultry, improve the immunity, relieve the stress, effectively control the cough and asthma and other respiratory diseases, and improve the production efficiency, and can also avoid drug residue caused by excessive use of chemicals and antibiotics, therefore the pharmaceutical composition can be widely used in the practice of culturing the livestock and poultry.

Description

technical field [0001] The invention belongs to the field of veterinary drugs, and in particular relates to a pharmaceutical composition for livestock and poultry cough and asthma and a preparation process thereof. Background technique [0002] Animal respiratory diseases are mainly caused by mycoplasma, bacteria, viruses, and harsh environments such as excessive ammonia concentration. Serous or mucous exudates in the trachea and bronchi, air sacculitis, pericarditis, perihepatitis, pneumonia, etc. The disease is extremely harmful to the livestock and poultry breeding industry. [0003] At present, various antibacterial drugs are most commonly used in the treatment of this disease, such as oxytetracycline, chloramphenicol, penicillin, streptomycin, quinolones, etc., because antibacterial drugs generally have the disadvantages of strong toxic side effects and easy drug resistance. , the curative effect is significantly reduced, and the drug remains in the animal body, and t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/70A61P11/14A61P11/06A61P31/00A61P11/00
CPCA61K36/31A61K36/07A61K36/19A61K36/195A61K36/315A61K36/428A61K36/535A61K36/539A61K36/605A61K36/70A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 尹朋张磊梁冰
Owner ZHONGYUEMINAN BEIJING TECH DEV CO LTD
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