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Applications of inflammation eliminating dina'er pharmaceutical composition in preparation of alcoholic fatty liver treating drugs

A technology of inflammatory and anti-oxidation, which is applied in the field of traditional Chinese medicine, can solve the problems of unresearched drugs, achieve good curative effect, improve the antioxidant level of liver cells, and prevent liver fibrosis

Inactive Publication Date: 2017-05-31
新疆维吾尔药业有限责任公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Therefore, drugs for the treatment of alcoholic fatty liver remain to be studied

Method used

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  • Applications of inflammation eliminating dina'er pharmaceutical composition in preparation of alcoholic fatty liver treating drugs
  • Applications of inflammation eliminating dina'er pharmaceutical composition in preparation of alcoholic fatty liver treating drugs
  • Applications of inflammation eliminating dina'er pharmaceutical composition in preparation of alcoholic fatty liver treating drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Give KM mice 50% alcohol by intragastric administration for 3 consecutive weeks to form a mouse model of alcoholic fatty liver. , liver tissue homogenate, viscera, pathological sections and other indicators to evaluate the pharmacodynamic effects of the tested drug on alcoholic fatty liver and compare it with the characteristics or advantages of similar drugs.

[0048] 1. Experimental materials

[0049] Animals: 70 Kunming (KM) mice, SPF grade, weighing 18-22 g, half male and half male, provided by Hunan Slake Jingda Experimental Animal Co., Ltd. Animal license number: SCXK (Xiang) 2013-0004.

[0050] Instruments: homogenizer, centrifuge, 96-well plate, 1.5ml Eppendorf tube, 5ml Eppendorf tube, 10ml Eppendorf tube, weighing balance, surgical instruments, microplate reader, light microscope.

[0051] Reagents and drugs: absolute ethanol and formaldehyde, provided by Sinopharm Chemical Reagent Co., Ltd.; Ganshuang Granules, provided by Baoding Tianhao Pharmaceutical Co.,...

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Abstract

The invention relates to applications of an inflammation eliminating dina'er pharmaceutical composition in preparation of alcoholic fatty liver treating drugs, and discloses an inflammation eliminating dina'er pharmaceutical composition, which comprises the root of cichorium intybus l, the seed of cichorium intybus l, rose, rheum palmatum l, nymphaea, anchusa italica, and dodder. According t the present invention, the inflammation eliminating dina'er pharmaceutical composition is used for treating alcoholic fatty liver, provides good treatment effects for alcoholic fatty liver, and can further treat various hepatitis, cholecystitis, and urinary tract infections.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a pharmaceutical composition of Yanxiao Dinaer and its application in the preparation of drugs for treating alcoholic fatty liver. Background technique [0002] The liver is an important detoxification organ of the human body, and the metabolic process of alcohol is mainly carried out in the liver. Long-term intake of large amounts of alcoholic beverages makes the liver exceed the detoxification capacity of normal physiological metabolism, leading to many important physiological, biochemical and metabolic imbalances in the body, severely damaging liver cells, and leading to alcoholic liver disease. Alcoholic liver disease (ALD) is a toxic liver disease characterized by hepatic steatosis, inflammatory cell infiltration, and even fibrosis caused by long-term heavy alcohol intake. According to statistics, the incidence of alcoholic fatty liver among alcoholics in our co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/738A61P1/16A61K31/366
Inventor 王学海尹强许勇尹海龙马璇穆丹丹苏海娣黄璐努尔拉江·帕合尔丁田芳刘腊才
Owner 新疆维吾尔药业有限责任公司
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