The invention relates to a nanostructured pure titanium plate preparation method which includes the following phases: (1) selection of titanium powder particles, to be more specific, low oxygen and low hydrogen high purity titanium powder particles are selected, and the titanium powder particle size distribution range is 5-200 microns; (2) preparation of a pure titanium plate blank by high speed spray deposition method, to be more specific, titanium powder particles are accelerated, by collision of the high speed titanium powder particles and a substrate, a pure titanium plate blank is prepared by deposition caused by strong plastic deformation of the titanium powder particles; (3) plate blank heat treatment, to be more specific, and heat treatment of the prepared pure titanium plate blank is performed; and (4) hot rolling. The crystalline grain size of the pure titanium plate prepared by the method is small, the crystalline grain is nanocrystalline, uniform in organization, and excellent in performance, the shortcoming of low strength of the pure titanium plate is overcome, the hardness is 2 times greater than that of ordinary pure titanium plates, at the same time, the advantages of excellent corrosion resistance, heat resistance and biocompatibility and the like of the ordinary pure titanium plates are inherited. The nanostructured pure titanium plate preparation method is simple in process, good in controllability, and high in production efficiency, and helps to industrial application.