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40results about How to "Unique chemical structure" patented technology

Abietate alcohol ether type quaternary ammonium salt surface active agent and preparation method thereof

The invention discloses an abietate alcohol ether type quaternary ammonium salt surface active agent. The general structural formula is as follows: the molecular weight n of polyethylene glycol (PEG) in the formula is any one in 200, 400, 600, 1000, 2000 and 4000, and in the formula, the R is any one in methyl CH3, ethyl CH2CH3, and ethanol base CH2CH2OH. The invention also comprises a preparation method of the surface active agent. The method comprise that a one-pot method is adopted, rosin and polyethylene glycol are subjected to esterification to form rosin polyethylene glycol monoester, hydroxide radical in the polyethylene glycol is subjected to etherification through epoxy chloropropane, and an epoxy group and tertiary amine hydrochloride are quaternized to obtain the abietate alcohol ether type quaternary ammonium salt surface active agent. The critical micelle concentration of prepared surface active agent is 0.1-0.3 mmol/L, and the range of surface tension is 37-39.5 mN/m. Molecules contain nonionic functional groups and cation functional groups, and the abietate alcohol ether type quaternary ammonium salt surface active agent is a novel functional environment-friendly surface active agent.
Owner:INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY

N-methoxyl formamide-orientated method for synthesizing ferrocene and pyridone derivative

The invention discloses an N-methoxyl formamide-orientated method for synthesizing a ferrocene and pyridone derivative. According to the method, under the conditions that palladium acetate is taken as a catalyst, copper acetate is taken as a catalyst promoter and quaternary ammonium salt and alkali are taken as additives, an N-methoxyl ferrocene and [c] pyridine-2(1H)-ketone derivative is obtained by carrying out a cyclization reaction on N-methoxyl ferrocene formamide and alkyne. The method adopts an N-methoxyl formamide-orientated carbon-hydrogen bond and nitrogen-hydrogen bond double-activation reaction to synthesize the N-methoxyl ferrocene and [c] pyridine-2(1H)-ketone derivative in one step. The organometallic condensed heterocyclic compounds are unique in structure, thus being hard to prepare by a conventional method; the method provided by the invention has the characteristics of being easy in obtaining of raw materials and mild in reaction conditions, not needing the protection of inert gas, being high in synthetic yield, and the like; therefore, a new way is provided for the synthesis of novel ferrocene and heterocyclic compounds, and the method has an important significance for expanding the application of the compounds in the fields such as medicinal chemistry, material chemistry, catalysts and the like.
Owner:SHANDONG NORMAL UNIV

Method for the synthesis of ferrocene and pyridone derivatives directed by n-methoxy formamide

The invention discloses an N-methoxyl formamide-orientated method for synthesizing a ferrocene and pyridone derivative. According to the method, under the conditions that palladium acetate is taken as a catalyst, copper acetate is taken as a catalyst promoter and quaternary ammonium salt and alkali are taken as additives, an N-methoxyl ferrocene and [c] pyridine-2(1H)-ketone derivative is obtained by carrying out a cyclization reaction on N-methoxyl ferrocene formamide and alkyne. The method adopts an N-methoxyl formamide-orientated carbon-hydrogen bond and nitrogen-hydrogen bond double-activation reaction to synthesize the N-methoxyl ferrocene and [c] pyridine-2(1H)-ketone derivative in one step. The organometallic condensed heterocyclic compounds are unique in structure, thus being hard to prepare by a conventional method; the method provided by the invention has the characteristics of being easy in obtaining of raw materials and mild in reaction conditions, not needing the protection of inert gas, being high in synthetic yield, and the like; therefore, a new way is provided for the synthesis of novel ferrocene and heterocyclic compounds, and the method has an important significance for expanding the application of the compounds in the fields such as medicinal chemistry, material chemistry, catalysts and the like.
Owner:SHANDONG NORMAL UNIV

Novel isopentenyl naphthoquinone obtained in active fraction for promoting blood circulation to remove blood stasis in clinopodium chinense (Benth.) O. Kuntze. and preparation method thereof

InactiveCN103664859AUnique chemical structureStrong activity of promoting blood circulation and removing blood stasisOrganic active ingredientsOrganic chemistryChemical compoundColumn chromatography
The invention relates to isopentenyl naphthoquinone obtained in the active fraction for promoting blood circulation to remove blood stasis in clinopodium chinense (Benth.) O. Kuntze. in a novel structure. A preparation method comprises the steps of extracting the dried overground part of clinopodium chinense (Benth.) O. Kuntze. by water; purifying and enriching an extract by macroporous resin to obtain a 50-95% ethanol eluate; then, enriching through alkali dissolution and acid deposition, and refining to obtain the active fraction of clinopodium chinense (Benth.) O. Kuntze.. One novel isopentenyl naphthoquinone is separated from the active fraction of clinopodium chinense (Benth.) O. Kuntze. through various separating technologies such as column chromatography and the like. The separated compound is identified by applying modern spectrum technologies (IR, UV, MS, 1D, 2D-NMR), and the compound is named as 2, 2-dimethyl-3, 10-dihydroxy-3, 4, 4a, 10b-tetrahydro-5H-naphtho[1, 2-b]-pyran-6-one (1). The novel isopentenyl naphthoquinone is characterized in that the compound is a polymer of naphthoquinone and/or isoamylene in a novel structure.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI
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