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Calcium supplement compound capable of introducing calcium into bone and preventing loss of bone calcium and preparation method thereof

A technology for bone calcium and calcium supplementation, applied in the field of calcium supplementation compound and its preparation, can solve the problems of poor bone supplementation effect, low calcium absorption rate, lack of bone calcium absorption, etc. Good calcium effect and the effect of improving the extraction rate

Active Publication Date: 2020-09-11
江苏天美健大自然生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Single calcium supplements include inorganic calcium: calcium carbonate, calcium hydrogen phosphate, etc., which contain relatively high calcium content, but have side effects such as heating, constipation, and gastrointestinal irritation; organic acid calcium: calcium gluconate, calcium lactate, calcium citrate, etc. , less side effects, but calcium gluconate, calcium lactate calcium content is very low, only 9% -12%, calcium citrate calcium content is 21%, but the price is expensive; organic calcium: amino acid chelated calcium, although High calcium absorption rate, no irritation to the gastrointestinal tract, but complicated preparation and high price
These calcium preparations are all from synthetic sources, or prepared by enzymatic methods or fermentation; as simple calcium preparations, the absorption rate is low, the effect of bone supplement calcium is not good, or the preparation is complicated and expensive
[0011] The calcium absorption rate of compound calcium supplements has been relatively improved, but such compound products have many ingredients and complex formulas, and because the formula lacks ingredients that promote bone calcium absorption or introduce calcium into the bone, the calcium absorption rate is still not high. And the effect of supplementing bone calcium is not good

Method used

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  • Calcium supplement compound capable of introducing calcium into bone and preventing loss of bone calcium and preparation method thereof
  • Calcium supplement compound capable of introducing calcium into bone and preventing loss of bone calcium and preparation method thereof
  • Calcium supplement compound capable of introducing calcium into bone and preventing loss of bone calcium and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Take tablets as an example:

[0073] A calcium supplement compound capable of introducing calcium into the bone and preventing loss of bone calcium. The following components are weighed in parts by weight: 30 parts of red deer bone powder, 30 parts of glucosamine hydrochloride, 20 parts of melon seed powder, and 15 parts of lactose 4 parts, 4 parts of sodium carboxymethyl starch, mixed uniformly, added 1 part of magnesium stearate, mixed uniformly, compressed into tablets.

[0074] Wherein, the preparation of red deer bone meal:

[0075] 1. Weigh fresh red deer bones with residual meat and periosteum, wash, crush, and coarsely crush them into broken bones with a particle size of ≤3mm;

[0076] 2. Add distilled water according to the material-to-liquid ratio of 1:2, boil in water for 60 minutes at 60°C and 200MPa in ultra-high pressure processing equipment;

[0077] 3. Cool to remove oil, add 5 times distilled water, enter the high-voltage pulse electric field, the fie...

Embodiment 2

[0083] Take capsules as an example:

[0084] A calcium supplement compound capable of introducing calcium into the bone and preventing loss of bone calcium. The following components are weighed in parts by weight: 50 parts of red deer bone powder, 25 parts of glucosamine sulfate, 10 parts of melon seed powder, and 12.5 parts of starch , mix evenly, add 2.5 parts of magnesium stearate, mix evenly, and pack into capsules.

[0085] Wherein, the preparation of red deer bone meal:

[0086] 1. Weigh fresh red deer bones with residual meat and periosteum, wash, crush, and coarsely crush them into broken bones with a particle size of ≤3mm;

[0087] 2. Add distilled water according to the material-to-liquid ratio of 1:4, boil in water for 30 minutes at 80°C and 200MPa in ultra-high pressure processing equipment;

[0088] 3. Cool to remove oil, add 3 times distilled water, enter the high-voltage pulse electric field, the field strength is 20kv / cm, and the number of pulses is 60 to obt...

Embodiment 3

[0094] Calcium Supplement Powder:

[0095] A calcium supplement compound capable of introducing calcium into the bone and preventing loss of bone calcium. The following components are weighed in parts by weight: 30 parts of red deer bone powder, 50 parts of glucosamine hydrochloride, 10 parts of melon seed powder, and 5 parts of lactose 4 parts, 4 parts of sucrose, mix well, add 1 part of magnesium stearate, mix evenly, subpackage.

[0096] Wherein, the preparation of red deer bone meal:

[0097] 1. Weigh fresh red deer bones with residual meat and periosteum, wash, crush, and coarsely crush them into broken bones with a particle size of ≤3mm;

[0098] 2. Add distilled water according to the material-to-liquid ratio of 1:4, boil in water for 50 minutes at 70°C and 150MPa in ultra-high pressure processing equipment;

[0099] 3. Cool to remove oil, add 5 times of distilled water, enter the high-voltage pulse electric field, the field strength is 25kv / cm, and the number of puls...

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PUM

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Abstract

The invention discloses a calcium-supplementing compound agent capable of introducing calcium into bones and preventing bone calcium loss. The calcium-supplementing compound agent is composed of the following components in parts by weight: 30-50 parts of red deer bone meal, 20-50 parts of D-glucosamine hydrochloride, 10-25 parts of muskmelon seed powder and the balance of auxiliary materials, and the total number of parts is 100. The invention further discloses a method for preparing the calcium-supplementing compound agent. The calcium-supplementing compound agent has the effects of supplementing calcium, promoting bone calcium absorption, inhibiting bone decomposition and preventing bone calcium loss. The muskmelon seed powder raw material is processed by degreasing and high voltage pulse combined Prote AX enzymic method, and the calcium supplementing effect is excellent.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a calcium supplement compound and a preparation method thereof. Background technique [0002] Calcium is one of the most widely distributed elements in nature. According to the composition ratio of elements in the human body, calcium ranks fifth after oxygen, carbon, hydrogen and nitrogen, and is the most abundant mineral element in the human body. When the human body is deficient in calcium, it stimulates hypersecretion of parathyroid hormone, which manifests as bone calcium absorption into the blood in the body, resulting in decreased bone calcium, osteoporosis, bone loss, increased calcium content in soft tissues and arteries, and calcium ions in cell membranes. Concentrations drop, eventually leading to a variety of disease phenomena. Children in the growing period need more calcium. Long-term calcium deficiency will lead to poor bone calcification, growth reta...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/16A23L33/165A23L13/20A23L13/40A23L33/175A23L33/18A23L33/125A23L25/00A23L5/10A23L5/30
CPCA23V2002/00A23V2200/306A23V2250/1578
Inventor 柳玲郁桦李玲王荣昌葛文金饶安平
Owner 江苏天美健大自然生物工程有限公司
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