Compound traditional Chinese medicine having whitening function and preparation method thereof

A functional, traditional Chinese medicine technology, applied in the directions of medical preparations containing active ingredients, pharmaceutical formulations, preparations for skin care, etc., can solve problems such as large side effects, skin pigmentation, easy decomposition, etc., achieve desalination of pigmentation, high content of active ingredients , the effect of promoting metabolism

Inactive Publication Date: 2017-06-16
韩丰河
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] It has a strong whitening effect, but it is easy to decompose when exposed to light and heat. Whitening preparations containing chemical ingredients or heavy metals are easy to cause skin pigmentation after use
[0009] deposition, side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] 1. Raw materials of traditional Chinese medicine compound with whitening function: 3 parts of Galla charcoal, 3 parts of Cortex Phellodendri, and 3 parts of Comfrey.

[0049] 2. The preparation method of the Chinese medicine compound with whitening function:

[0050] First, take Galla carbs and fry for 20-30 minutes to get Galla carbs, take 3 parts galla carbs, 3 parts Phellodendron cortex and 3 parts comfrey

[0051] Parts were dried overnight in an oven, crushed and sieved through a 40-mesh sieve, set aside, then added water 7 times the amount of medicinal materials, heated and refluxed for 1 hour

[0052] , filter, add 3 times the amount of water to the filter residue, heat and reflux for extraction for 1 hour, combine the extracts, filter, take the filtrate, concentrate the medicinal solution, add 95% ethanol to make the ethanol concentration 70%, let it stand for precipitation, and take Concentrate the filtrate, add 0.2%-0.3% activated carbon, heat at 80-90°C for ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine compound with whitening function and its preparation method and application. It is prepared from the following raw materials in parts by weight: 3-10 parts of Galla charcoal, 3-10 parts of Cortex Phellodendri, 3-10 parts of Comfrey share. The traditional Chinese medicine compound provided by the present invention, according to the theory of traditional Chinese medicine, adopts the theory of syndrome differentiation and treatment to carry out the prescription of traditional Chinese medicine proportioning. The experimental results show that the traditional Chinese medicine compound provided by the present invention has good inhibition of tyrosinase activity and inhibition of melanin production in B16F10 cells , Inhibiting the proliferation of B16F10 cells and promoting the apoptosis of B16F10 cells, it has a definite whitening effect, and the Chinese medicine compound extract is safe to use, has no toxic side effects, stable quality, can be prepared into a variety of daily necessities, and is expected to be developed into a new generation of whitening products preparation.

Description

technical field [0001] The invention relates to a compound Chinese medicine, in particular to a compound Chinese medicine with whitening function and a preparation method thereof [0002] and its application. Background technique [0003] The color of the skin mainly depends on the amount of melanin contained in the skin. Melanocytes in the epidermis [0004] Its synthesis is affected by various enzymes in the cell, including tyrosinase, dopachrome isomerase, 5,6-dioxindole-2-carboxylic acid (DHICA) oxidase, etc. Among them, tyrosinase is the main rate-limiting enzyme, and the activity of this enzyme determines the [0005] The number of elements formed. In addition, the synthesis of melanin is also affected by factors such as ultraviolet rays and free radicals. [0006] Most of the current whitening products mainly focus on inhibiting tyrosinase. These existing drugs, in terms of stability, side effects [0007] The use, effect and other aspects are not satisfactory....

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P17/00A61P17/10A61K8/98A61K8/9789A61Q19/02A61Q19/08A61Q17/04A61K35/64
CPCA61K36/756A61K8/97A61K8/987A61K36/30A61K2236/331A61K2236/39A61K2236/53A61K2800/522A61K2800/782A61Q17/04A61Q19/02A61Q19/08
Inventor 韩丰河
Owner 韩丰河
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