Method for preparing ellagic acid concentrate by using branches and leaves of rubus corchorifolius

A technology of ellagic acid and concentrates, which is applied in the field of efficient and comprehensive utilization of agricultural products and by-products, can solve environmental pollution and other problems, and achieve the effect of low investment cost, low cost, and easy large-scale production

Inactive Publication Date: 2017-07-04
HEBEI AGRICULTURAL UNIV.
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

According to the planting area of ​​raspberries in 2012, the discarded raspberry branches and leaves after raspberry stubble reached more than 30,000 tons each year, and it increased year...

Method used

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  • Method for preparing ellagic acid concentrate by using branches and leaves of rubus corchorifolius
  • Method for preparing ellagic acid concentrate by using branches and leaves of rubus corchorifolius

Examples

Experimental program
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Effect test

Embodiment 1

[0026] Dry the raspberry branches and leaves of the flat stubble until the water content is 6.8%, crush them to 40 mesh, take 20g of raspberry branch powder, add 1000ml of 50% ethanol (containing 1.2mol hydrochloric acid) solution, extract at 85°C for 150min, 0.1MPa , concentrated to 350ml at 75°C, cooled to 23°C and placed in a refrigerator at 4.8°C for 14 hours, then filtered with 200 mesh and washed with 30ml of distilled water six times until neutral, then dried at 53°C to The moisture content was 6.8%, and 1.28 g of solid powder was obtained, and the measured ellagic acid content was 16.9%.

Embodiment 2

[0028] Dry the raspberry branches and leaves of the flat stubble until the water content is 7.0%, crush them to 40 mesh, take 10g of raspberry branch powder, add 550ml of 50% ethanol (containing 0.82mol hydrochloric acid) solution, extract at 85°C for 140min, 0.1MPa , concentrated to 170ml at 70°C, cooled to 20°C and placed in a refrigerator at 4.3°C for 15 hours, then filtered with 200 mesh and washed with 18ml of distilled water six times until neutral, then dried at 53°C to The moisture content was 7.2%, and 0.65 g of solid powder was obtained, and the measured ellagic acid content was 17.2%.

Embodiment 3

[0030] Dry the raspberry branches and leaves of the flat stubble until the water content is 7.0%, crush them to 40 mesh, take 20g of raspberry branch powder, add 1200ml of 50% ethanol (containing 2.2mol hydrochloric acid) solution, extract at 84°C for 140min, 0.1MPa , concentrated to 380ml at 70°C, cooled to 25°C and placed in a refrigerator at 3.8°C for 16 hours, then filtered with 200 mesh and washed with 36ml of distilled water six times until neutral, then dried at 58°C to The moisture content was 7.8%, and 1.4 g of solid powder was obtained, and the measured ellagic acid content was 18.7%.

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Abstract

The invention relates to a method for preparing an ellagic acid concentrate by using the branches and the leaves of rubus corchorifolius. Naturally extracted compound ellagic acid only destroys bad cells in human body (the daily metabolic products of human body comprise thousands to thousands of cancer cells), and cannot damage good cells in human body, such that the formation of cancer cells can be prevented by usually intaking the nutrient, and the ellagic acid is the optimal natural anticancer supplementing food. According to the present invention, the residual branches and the residual leaves of rubus corchorifolius after the stumping are adopted as the raw material, reflux is performed for 120-180 min at a temperature of 80-90 DEG C by using a hydrochloric acid concentration of 1.2-2.0 mol/L and an ethanol concentration of 45-55% according to a material-liquid ratio of 1:50-60 (m/v), and vacuum concentration and cooling precipitation are performed to obtain the ellagic acid concentrate with the ellagic acid content of more than 16%.

Description

technical field [0001] The invention belongs to the technical field of high-efficiency comprehensive utilization of agricultural products and by-products, and in particular relates to a solvent removal and extraction aid method after extracting ellagic acid in raspberry branches with a solvent. Background technique [0002] There are long records of raspberry medicine in our country. It is recorded in "Qianjin Shizhi" that raspberry is "sweet, flat, and non-toxic". Improving eyesight, treating impotence, nocturnal emission, weakness, fatigue, and dark eyes, it is a traditional folk medicine of the Miao nationality. Its root, lotus, and leaves can be used as medicine. The root is slightly bitter in nature and taste. It has the effects of dispelling wind, activating blood, detoxifying and astringing drag. As of 2012, the planting area of ​​raspberry in my country has reached 180,000 mu, and the planting area of ​​raspberry has increased rapidly in the past three years. Accor...

Claims

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Application Information

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IPC IPC(8): A61K36/73A23L33/105G01N30/02C07D493/06
CPCA61K36/73A61K2236/333A61K2236/51A61K2236/53C07D493/06G01N30/02G01N2030/027
Inventor 田益玲李保国叶亚杰张雪梅顾玉红李峻
Owner HEBEI AGRICULTURAL UNIV.
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