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Traditional Chinese medicine composition and application thereof in preparation of products for preventing H7 subtype avian influenza virus

A kind of bird flu virus and composition technology, applied in antiviral agents, drug combinations, medical preparations containing active ingredients, etc., can solve the problems of drug shortage, achieve good therapeutic effect, improve the degree of pneumonia lesions, and significantly antiviral effect of ability

Inactive Publication Date: 2017-07-04
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current drugs for the treatment of influenza A virus infection are far from enough, and it is necessary to further develop drugs with anti-influenza virus function

Method used

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  • Traditional Chinese medicine composition and application thereof in preparation of products for preventing H7 subtype avian influenza virus
  • Traditional Chinese medicine composition and application thereof in preparation of products for preventing H7 subtype avian influenza virus
  • Traditional Chinese medicine composition and application thereof in preparation of products for preventing H7 subtype avian influenza virus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: the preparation method of Chinese medicine composition

[0036] According to parts by weight, it is respectively 10 parts of shiitake mushrooms, 10 parts of poria cocos, 10 parts of ginger, and 30 parts of tangerine peel. Weigh mushrooms, tuckahoe cocos, ginger and tangerine peel, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, Decoct for 1 hour, filter, and combine the two filtrates; concentrate the filtrate to contain 100g of crude drug per 100mL, freeze-dry or dry at 70°C, and pulverize to obtain the traditional Chinese medicine composition.

Embodiment 2

[0037] Embodiment 2: the preparation method of Chinese medicine composition

[0038] According to parts by weight, there are 5 parts of shiitake mushrooms, 5 parts of poria cocos, 5 parts of ginger, and 60 parts of tangerine peel. Weigh mushrooms, tuckahoe cocos, ginger and tangerine peel, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, Decoct for 1 hour, filter, and combine the two filtrates; concentrate the filtrate to contain 100g of crude drug per 100mL, freeze-dry or dry at 70°C, and pulverize to obtain the traditional Chinese medicine composition.

Embodiment 3

[0039] Embodiment 3: the preparation method of Chinese medicine composition

[0040] According to parts by weight, there are 5 parts of shiitake mushrooms, 5 parts of poria cocos, 5 parts of ginger, and 30 parts of tangerine peel. Weigh mushrooms, tuckahoe cocos, ginger and tangerine peel, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, Decoct for 1 hour, filter, and combine the two filtrates; concentrate the filtrate to contain 100g of crude drug per 100mL, freeze-dry or dry at 70°C, and pulverize to obtain the traditional Chinese medicine composition.

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Abstract

The invention discloses a formula, which contains a water extract of mushroom, poria cocos, ginger, and dried orange peel and can prevent H7 subtype avian influenza virus, and an application thereof. The formula is mainly composed of mushroom, poria cocos, ginger, and dried orange peel. The anti-virus experiment results show that the formula can prominently enhance the immunity of mice infected by H7 subtype avian influenza virus; the pneumonia lesion degree of the mice is improved; the specific antibody level in the serum of the mice is obviously improved; the number of viruses in the lung of the mice is prominently reduced; the lung cell factor IL-2 level is improved; and the in-vitro cell test results show that the traditional Chinese medicine composition has a prominent antivirus performance and good curative effect. The formula has a good effect on preventing H7 subtype avian influenza virus.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition and its application in the preparation of anti-H7 subtype avian influenza virus products. Background technique [0002] Avian Influenza (AI) is a poultry disease caused by influenza virus A in the family Orthomyxoviridae. Once AI occurs, it will not only seriously hinder the stable development of the poultry industry, but also cause harm to human health and affect society. problems of economic development. [0003] There are three types of avian influenza virus (AIV): A, B, and C. Among them, influenza A viruses are mostly found in poultry, and some types of influenza A can also infect various mammals and humans such as pigs, horses, seals and whales; influenza B and C viruses are respectively found in seals and pigs. Among them, avian influenza A virus is an enveloped, polymorphic single-stranded negative-sense RNA virus. The genome is divid...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K39/39A61P31/16A61P37/04
CPCA61K36/9068A61K39/39A61K36/07A61K36/076A61K36/752A61K2039/55588A61K2300/00
Inventor 尹西拳胡明华马方励马忠华
Owner INFINITUS (CHINA) CO LTD
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