Compound gel preparation for treating radiodermatitis and preparation method thereof

Abstract

The invention discloses a compound gel preparation for treating radiodermatitis and a preparation method thereof. The compound gel preparation is prepared from the following components in parts by mass: 1-10 parts of superficial anesthesia, 0.1-1 part of glucocorticoid, 0.1-1 part of androgen, 500 parts of an oil phase, 1.4-14 parts of hydrogel matrix, 2-20 parts of a burn anti-infectious agent, 4-300 parts of alcohol and 200-500 parts of water. The compound gel preparation has an excellent prevention and treatment effect for the radiative skin reaction of tumor patients, has the effects of diminishing inflammation, relieving pain, promoting patient wound healing, nourishing skin, repairing skin injury and the like, can be used for remarkably reliving pains of patients with radiodermatitis, is greatly beneficial to continuous radiotherapy for tumor patients. The medicine is an emulsion which has strong skin affinity, is convenient to use and can be easily removed, and can be used for improving the compliance of patients.

Description

technical field [0001] The invention relates to a compound gel preparation for treating radiation dermatitis and a preparation method thereof. Background technique [0002] At present, the main means of treating tumors include surgery, radiotherapy, and chemotherapy. Radiotherapy plays an important role in tumor treatment, and its clinical application is very extensive. According to statistics, about 60% to 70% of tumor patients will receive radiotherapy at different periods. However, while playing the role of treating tumors, radiation can also cause damage to normal skin tissue, leading to radiation dermatitis. Sexual necrosis and degeneration. If an ulcer is formed, the formation of granulation tissue and vascular network is affected, so the wound is difficult to heal, which may cause long-term infection and deep tissue damage, which will affect the continued radiotherapy. According to statistics, about 87% of patients who receive radiotherapy will have radiation skin r...

AI Technical Summary

Problems solved by technology

[0004] At present, there are certain limitations in the treatment methods of western medicine. The treatment of radiation dermatitis by western medicine is mainly local treatment. Skin flap transplantation, but the success rate of flap transplantation is low due to insufficient basal nutrient supply

[0005] The treatment of radiation dermatitis by traditional Chinese medicine has not been widely recognized clinically. Its limitations are mainly reflected in the inaccurate curative effect and inconvenient use. Among them, burn ointment is the most commonly used clinically, but its therapeutic effect on radiation dermatitis is not ideal.