Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A traditional Chinese medicine composition for preventing and treating myocardial fibrosis and its application

A technology of myocardial fibrosis and composition, which is applied in the field of Chinese medicine compound preparations, can solve problems such as the inability to reflect the multi-component, multi-target, and multi-path effects of traditional Chinese medicine and Chinese medicine compound, and achieve excellent prevention and treatment of myocardial fibrosis and improvement of wall adhesion , Improve the effect of energy utilization efficiency

Active Publication Date: 2020-11-24
YANTAI UNIV
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current research on the role of traditional Chinese medicine in the prevention and treatment of myocardial fibrosis mostly selects a single Chinese medicine or active ingredients of traditional Chinese medicine to act on several representative and relatively well-studied regulatory factors and signaling pathways, which cannot reflect the effects of traditional Chinese medicine and traditional Chinese medicine. The compound has the characteristics of multi-component, multi-target, and multi-way action, and there are certain deficiencies and defects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A traditional Chinese medicine composition for preventing and treating myocardial fibrosis and its application
  • A traditional Chinese medicine composition for preventing and treating myocardial fibrosis and its application

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0028] A traditional Chinese medicine composition for preventing and treating myocardial fibrosis, comprising:

[0029] Sovereign medicine, its weight portion is 65 parts, and it comprises the turmeric and Corydalis chinensis that the weight ratio is 6:1;

[0030] Chenyao, which comprises the following weight components: 12 parts of sweet potato vines, 12 parts of Ophiopogon japonicus, 8 parts of cinnamon twigs and 6 parts of Codonopsis pilosula;

[0031] An adjuvant, which comprises the following weight components: 10 parts of clove grass, 10 parts of raw ground and 8 parts of white scallops;

[0032] Use medicine, which includes 8 parts by weight of Paeonia lactiflora.

[0033] The components of the traditional Chinese medicine compound preparation are respectively washed, dried and pulverized into particles with a particle size of less than 300 μm, and after being uniformly mixed, they are then subjected to dynamic extraction with 93° C. hot water for 30 minutes, decoloriz...

example 2

[0037] A traditional Chinese medicine composition for preventing and treating myocardial fibrosis, comprising:

[0038] Sovereign medicine, its weight portion is 65 parts, and it comprises the turmeric and Corydalis chinensis that the weight ratio is 6:1;

[0039] Chenyao, which comprises the following weight components: 18 parts of sweet potato vine, 18 parts of Ophiopogon japonicus, 12 parts of Guizhi and 10 parts of Codonopsis;

[0040] An adjuvant, which comprises the following weight components: 15 parts of clove grass, 15 parts of raw ground and 12 parts of white scallops;

[0041] Use medicine, which includes 8 parts by weight of Paeonia lactiflora.

[0042] The components of the traditional Chinese medicine compound preparation are respectively washed, dried and pulverized into particles with a particle size of less than 300 μm, and after mixing uniformly, dynamic extraction with hot water at 95° C. for 50 minutes, decolorization resin, ultrafiltration, nanofiltration...

example 3

[0046]A traditional Chinese medicine composition for preventing and treating myocardial fibrosis, comprising:

[0047] Sovereign medicine, its weight portion is 65 parts, and it comprises the turmeric and Corydalis chinensis that the weight ratio is 6:1;

[0048] Chenyao, which comprises the following weight components: 15 parts of sweet potato vine, 15 parts of Ophiopogon japonicus, 10 parts of Guizhi and 8 parts of Codonopsis;

[0049] Adjuvant, which comprises the following weight components: 13 parts of clove grass, 13 parts of raw ground and 10 parts of white scallops

[0050] Use medicine, which includes 8 parts by weight of Paeonia lactiflora.

[0051] The components of the traditional Chinese medicine compound preparation are respectively washed, dried, and pulverized into particles with a particle size of less than 300 μm, and after mixing uniformly, they are then subjected to dynamic extraction with hot water at 94° C. for 40 minutes, decolorizing resin, ultrafiltra...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention provides a myocardial fibrosis preventing Chinese herb composition. The myocardial fibrosis preventing Chinese herb composition is composed of, by weight part, 65 parts of monarch herbs composed of turmeric and corydalis tuber at a weight ratio of 6:1, ministerial herbs including 12-18 parts of ficus tikoua, 12-18 parts of radix ophiopogonis, 8-12 parts of cassia twig and 6-10 parts of codonopsis pilosula, adjuvant herbs including 10-15 parts of zornia gibbosa, 10-15 parts of radix rehmanniae and 8-12 parts of radix ampelopsis, and conductant herbs of 8 parts of liquorice. The myocardial fibrosis preventing Chinese herb composition is a powder or granulated product obtained sequentially through hot water dynamic extraction, resin decoloration, ultrafiltration, nanofiltration concentration and spray drying. The myocardial fibrosis preventing Chinese herb composition is reasonable in composition and prescription; the herbs are mutually balanced and coordinated to achieve outstanding myocardial fibrosis preventing effects. Meanwhile, according to the myocardial fibrosis preventing Chinese herb composition, a Chinese herb extracting solution is processed through spray drying, and by adding composite auxiliary materials composed of dextrin, lactose, sorbitol and aerosil, wall adhesion of the Chinese herb extracting solution during the spray drying process can be significantly improved.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine compound preparation. More specifically, the present invention relates to a traditional Chinese medicine composition for preventing and treating myocardial fibrosis. Background technique [0002] Myocardial fibrosis refers to the excessive accumulation of collagen fibers in the tissue structure of the myocardium, a significant increase in its collagen concentration or a significant increase in the collagen volume fraction. In recent years, a large number of studies have shown that myocardial fibrosis can occur in many cardiovascular diseases such as hypertension, myocardial infarction and heart failure. It is a common pathological change in the development of various heart diseases to a certain stage, and is one of the main manifestations of myocardial remodeling, which can lead to increased myocardial stiffness, decreased ventricular diastolic function, decreased coronary reserve, and ev...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/16A61K47/36A61K47/26A61K47/04A61P9/00
CPCA61K9/1611A61K9/1623A61K9/1652A61K36/344A61K36/48A61K36/484A61K36/54A61K36/60A61K36/66A61K36/804A61K36/87A61K36/8968A61K36/9066A61K2236/331A61K2236/51A61K2300/00
Inventor 李春梅高永林
Owner YANTAI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com