Cationic bactericidal gel, preparation method thereof and bacteriostatic aloe gel product containing same

A bactericidal gel and cationic technology, which is applied in the direction of medical preparations, cosmetic preparations, and dressing preparations containing active ingredients, can solve the problems of unpleasant use of gels, and achieve no skin dependence and side effects, Delay skin aging, good antibacterial effect

Inactive Publication Date: 2017-11-24
平舆玛雅生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Based on the deficiencies of the prior art, the object of the present invention is to provide a cationic bactericidal gel, which is made through an anionic carbogen gel and cationic bactericide through a specific ratio and process, which overcomes the traditional anionic carbogen and cationic bactericidal gel. The problem of flocculent precipitation will occur after the agent is mixed, and it also improves the sticky and unpleasant feeling of use of the gel agent

Method used

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  • Cationic bactericidal gel, preparation method thereof and bacteriostatic aloe gel product containing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A cationic bactericidal gel, made of the following raw materials in parts by weight: 0.1 part of hexamidine diisethionate, 0.04 part of benzalkonium chloride, 0.06 part of cetylpyridinium chloride, and 0.55 part of carbopol U20 , Carbo U21 0.4 parts, propylene glycol 7 parts, aminomethyl propanol 0.9 parts, water 90.95 parts.

[0035] The preparation method of above-mentioned cationic sterilization gel, comprises the following steps:

[0036] (1) Weigh each raw material according to parts by weight; dilute aminomethyl propanol 10 times with water to obtain the preparation 1;

[0037] (2) Wet and disperse Carbopol U20 and Carbopol U21 in the remaining amount of water, then add hexamidine diisethionate, benzalkonium chloride, cetylpyridinium chloride and propylene glycol, stir and mix well, then Heating to 80°C, stirring at a constant temperature for 30 minutes under the condition of a vacuum degree of 0.08 MPa, to obtain the preparation 2;

[0038] (3) Slowly add mater...

Embodiment 2

[0042] A cationic bactericidal gel, made of the following raw materials in parts by weight: 0.06 part of hexamidine diisethionate, 0.02 part of benzalkonium chloride, 0.03 part of cetylpyridinium chloride, and 0.5 part of carbopol U20 , 0.3 parts of Carbo U21, 6 parts of propylene glycol, 0.8 parts of aminomethyl propanol, and 92.29 parts of water.

[0043] The preparation method of above-mentioned cationic sterilization gel, comprises the following steps:

[0044] (1) Weigh each raw material by parts by weight; dilute aminomethyl propanol 9 times with water to obtain the preparation 1;

[0045] (2) Wet and disperse Carbopol U20 and Carbopol U21 in the remaining water, then add hexamidine diisethionate, benzalkonium chloride, cetylpyridinium chloride and propylene glycol, stir and mix well, then Heating to 50°C, stirring at a constant temperature for 60 minutes under the condition of a vacuum degree of 0.09 MPa, to obtain the preparation 2;

[0046] (3) Slowly add material 1...

Embodiment 3

[0050] A cationic bactericidal gel, made of the following raw materials in parts by weight: 0.2 part of hexamidine diisethionate, 0.05 part of benzalkonium chloride, 0.1 part of cetylpyridinium chloride, and 0.8 part of carbopol U20 , 0.5 parts of Carbo U21, 9 parts of propylene glycol, 1 part of aminomethyl propanol, and 88.35 parts of water.

[0051] The preparation method of above-mentioned cationic sterilization gel, comprises the following steps:

[0052] (1) Weigh each raw material according to parts by weight; dilute aminomethyl propanol 11 times with water to obtain raw material 1;

[0053] (2) Wet and disperse Carbopol U20 and Carbopol U21 in the remaining water, then add hexamidine diisethionate, benzalkonium chloride, cetylpyridinium chloride and propylene glycol, stir and mix well, then Heating to 65°C, stirring at a constant temperature for 45 minutes under the condition of a vacuum degree of 0.07 MPa, to obtain the preparation 2;

[0054] (3) Slowly add materia...

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Abstract

The invention discloses cationic bactericidal gel. Each 100 parts of the cationic bactericidal gel is prepared from the following raw materials in parts by weight: 0.05-0.5 part of hexamidine dihydroxyethyl sulfonate, 0.02-0.2 part of benzalkonium chloride, 0.03-0.3 part of cetylpyridinium chloride, 0.5-2 parts of carbomer U20, 0.3-1.5 parts of carbomer U21, 5-10 parts of propylene glycol, 0.5-2 parts of aminomethyl propanol and the balance of water. The invention further discloses a preparation method of the cationic bactericidal gel and a bacteriostatic aloe gel product containing the same. The problem that in the conventional technology, after an anionic carbomer and an anionic bactericide are mixed, a flocculent precipitate is produced is solved; the obtained bacteriostatic aloe gel product not only has the efficacies of activating cell vitality, delaying skin aging, eliminating inflammation, astringing and conditioning skin and the like, but also has good antibacterial and bacteriostatic effects; in addition, after the bacteriostatic aloe gel product is used, the skin feels fresh, cool and non-sticking; and the bacteriostatic aloe gel product is safe and free of side effects.

Description

technical field [0001] The invention belongs to the technical field of disinfection products, and in particular relates to a cationic bactericidal gel, a preparation method thereof, and an aloe antibacterial gel product containing the cationic bactericidal gel. Background technique [0002] Aloe is an evergreen herb of Liliaceae and Aloe genus. It has the characteristics of thick flesh and rich juice. There are more than 300 varieties, which are widely distributed in tropical and subtropical regions. Common representative three aloe species are American Aloe vera, Japanese Aloe arborescens and Aloe sinensis. American aloe vera has large and thick leaves with good quality, Japanese aloe vera has small and thin leaves, and Chinese aloe grows fast and has strong reproductive ability. [0003] There are two main types of chemical components of aloe, one is the quinones such as aloin that exist at the bottom of the aloe leaves and near the epidermis, and the other is the aloe ge...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/73A61K8/04A61K8/41A61K8/46A61K8/49A61K8/65A61Q17/00A61Q19/00A61Q19/08A61P31/02A61P29/00A61P17/02A61P17/10A61P17/04
CPCA61K8/042A61K8/416A61K8/466A61K8/4926A61K8/65A61K8/735A61K8/97A61K2800/75A61Q17/005A61Q19/00A61Q19/08
Inventor 黄冰燃
Owner 平舆玛雅生物工程有限公司
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