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Device For Measuring Concentration Of Substance In Blood, And Method For Measuring Concentration Of Substance In Blood

A technology of substance concentration and measuring device, which is applied in the direction of scattering characteristic measurement, diagnostic recording/measurement, instrument, etc., and can solve problems such as unclear band ownership

Active Publication Date: 2017-12-01
NAT INST FOR QUANTUM & RADIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The general reason for this is that in the case of near-infrared light, the absorption signal is very weak compared to infrared light due to the processing of higher harmonics of glucose (consonance or chord of standard vibrations in the mid-infrared band), and The attribution of the band is unclear

Method used

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  • Device For Measuring Concentration Of Substance In Blood, And Method For Measuring Concentration Of Substance In Blood
  • Device For Measuring Concentration Of Substance In Blood, And Method For Measuring Concentration Of Substance In Blood
  • Device For Measuring Concentration Of Substance In Blood, And Method For Measuring Concentration Of Substance In Blood

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Embodiment Construction

[0062] Hereinafter, a blood glucose meter (blood substance concentration measuring device) or a blood glucose level measuring method (blood substance concentration measuring method) according to an embodiment of the present invention will be described. figure 1 is a diagram showing the configuration of the blood glucose meter 1 . This blood glucose meter 1 is a non-invasive type, and the laser light (first laser light) 100 generated by the light source 10 is partially irradiated to the living epithelium (biological body) F of the subject, and the diffused reflected light (first diffused reflected light) 200 is irradiated. The photodetector (photodetector) 40 detects. The substance contained in the blood to be measured here is glucose. In addition, as described in Patent Document 3, the glucose concentration in the epithelial interstitial fluid is measured not exactly in blood, and can be recognized as a blood sugar level. In this case, although it is necessary to measure the...

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Abstract

The present invention measures the concentration of a substance in blood noninvasively, with high accuracy, and using a simple configuration. Laser light 100 generated by a light source 10 is locally radiated into the bodily epithelium (the body) F of a subject, and diffuse reflected light 200 therefrom is detected by a light detector (a light detection unit) 40. The laser light 100 that is used is mid-infrared light, has a wavelength of, for example, 9.26 mum, and is oscillated by the light source 10. The light source 10 generates the laser light 100 by using an OPO (an optical parametric oscillator) 12 to simultaneously lengthen the wavelength of and amplify pulsed excitation light 101 that is oscillated from an excitation-light source 11. An approximately tabular window 30 that is configured from a material that is transparent to mid-infrared light is provided between a light-guiding unit 20 and the bodily epithelium F. The window 30 and the bodily epithelium F are in tight contact. Glucose concentration in interstitial fluid can be calculated using a normalized light intensity that is calculated from the signal ratio between the light detector 40 and a monitor light detector 16.

Description

technical field [0001] The present invention relates to a blood substance concentration measurement device and a blood substance concentration measurement method for noninvasively measuring blood substances (glucose, lipid, etc.). Background technique [0002] In recent years, the population of lifestyle-related diseases has been increasing due to obesity due to lack of exercise and accumulation of stress. Lifestyle-related diseases are caused by metabolic syndrome in which blood sugar / lipid / blood pressure rise. Therefore, for the prevention and treatment of lifestyle-related diseases, it is important to check the status of blood sugar levels, blood lipid levels, and blood pressure levels on a daily basis. Among them, patients with diabetes, which is one of lifestyle-related diseases, are required to perform daily management of blood sugar levels in order to prevent serious complications. Here, the blood sugar level is specifically the concentration of glucose contained in ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/1455
CPCA61B5/14546A61B5/1455A61B5/14532A61B2562/0233G02F1/3501G02F1/39G02F1/3507G01N21/55A61B2090/306A61B2090/3614H01S3/1603H01S3/1643H01S3/2232
Inventor 山川考一
Owner NAT INST FOR QUANTUM & RADIOLOGICAL SCI & TECH