Biosensor, preparation method and target molecule concentration detection method thereof
A technology of biosensors and target molecules, which is applied in biological testing, instruments, measuring devices, etc., can solve the problems of limiting the application of antibody antigens, time-consuming, and reduced activity, and achieves a simple and fast detection process, no immunogenicity, and improved The effect of stability
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment Construction
[0029] The concept of the present invention is: the nucleic acid aptamer (Apatamer) is a single-stranded nucleic acid molecule with a specific recognition function, which can be synthesized in vitro through the ligand system evolution technology of exponential enrichment. Through research, it is found that in the presence of a target (that is, a target molecule), aptamers will undergo adaptive folding to form three-dimensional structures, such as G-quadruplexes, hairpins, convex rings, and pseudoknots. Tightly bind to the target through complementary base pairing, shape complementarity, van der Waals force, electrostatic interaction and hydrogen bond. There is a one-to-one correspondence between the target and its nucleic acid aptamer. For example, target A will fold its corresponding aptamer B to form a three-dimensional structure; target A1 will fold the corresponding aptamer B1 to form a three-dimensional structure. Furthermore, in contrast to antibodies, aptamers are easy ...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com