Cream for blocking nose allergen

A technology for allergens and creams, applied in allergic diseases, ointment delivery, emulsion delivery, etc., can solve problems such as lack of security, achieve good ductility, relieve nasal congestion, and improve rheological properties.

Inactive Publication Date: 2017-12-26
HC SYNTHETIC PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patent CN200910104987.3 discloses a production method of vaseline with different consistency. By controlling parameters such as pressure, temperature, and material ratio in each reaction process, vaseline with different penetrations can be obtained. The reaction process requires high temperature in the presence of hydrogen. , High pressure response, safety cannot be guaranteed

Method used

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  • Cream for blocking nose allergen
  • Cream for blocking nose allergen
  • Cream for blocking nose allergen

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation mode of sample among the embodiment 1 is as follows:

[0025] According to the above prescription, mix the components at 70°C. After the components are completely melted, stir at 250rpm for 20 minutes, cool down to 50°C, and pour into the mold.

Embodiment 2~5

[0026] Embodiment 2~5 preparation method, with embodiment 1.

Embodiment 4

[0027] Example 4 Determination of rheological parameters

[0028] Test method: Melting point, dynamic viscosity, cone penetration, respectively refer to melting point determination method ("Chinese Pharmacopoeia" 2015 edition four, general rule 0612 third method), viscosity determination method ("Chinese Pharmacopoeia" 2015 edition four, general rule 0633 second method ), cone penetration determination method ("Chinese Pharmacopoeia" 2015 Edition, Part Two, Appendix 0983) for determination.

[0029] tester:

[0030] Sample: the product prepared in embodiment 1 ~ 5 is as sample 1 ~ 5;

[0031] Reference substance: reference substance 1, medicinal white petrolatum as the reference substance; reference substance 2, Tice pollen blocker.

[0032] Sample results: see Table 1.

[0033] Table 1 Rheological parameters of different samples

[0034]

[0035] From the results in Table 1, it can be seen that the ratio of rheological parameters to white petrolatum (reference 1...

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Abstract

The invention belongs to the field of pharmacy and pharmacy, and in particular relates to a cream for blocking nasal allergens. The cream for blocking nasal allergens of the present invention is composed of vaseline and a rheology regulator, and has good extensibility. Applying this product to the nasal cavity can effectively prevent pollen, dust, house dust mites or animals from flowers, plants and trees. An allergic reaction to an allergen such as hair.

Description

technical field [0001] The invention belongs to the field of pharmacy and pharmacy, and relates to a cream for blocking nasal allergens. Background technique [0002] The prevalence of allergic rhinitis is high and rising, and has become a global disease of international concern. Preliminary research on the population in central cities in my country shows that the average self-reported prevalence rate is about 11.1%, with great differences in different regions. The allergens that cause allergic rhinitis are mainly airborne allergens, such as house dust, dust mites, insect fur, pollen, fungi, and non-specific irritants such as formaldehyde, etc., followed by ingested allergens, such as eggs, milk etc. Even low levels of exposure can induce allergic reactions. At present, there are three solutions to allergic rhinitis and asthma: one is to avoid allergens and prevent allergic reactions. The second is anti-inflammatory treatment: use antihistamines and local hormones. This ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/01A61K9/06A61K47/44A61K47/06A61P37/08A61P11/02
CPCA61K31/01A61K9/0043A61K9/06A61K47/06A61K47/44
Inventor 陆华龙戚苏民马涛
Owner HC SYNTHETIC PHARMA CO LTD
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