Efficient synthesis method of 1-(3-nitry-2-pyridine)-1H-benzotriazole compound

Abstract

The invention discloses an efficient synthesis method of a 1-(3-nitry-2-pyridine)-1H-benzotriazole compound. The synthesis method comprises the following steps: (1) weighing a certain solvent, addinga certain amount of benzotriazole raw material under the stirring state, adding a 2-chlorine-3-nitropyridine raw material with molar weight equal to that of the benzotriazole raw material, finally adding a certain amount of anhydrous sodium carbonate to form reaction liquid and maintaining the stirring state; (2) putting the reaction liquid into constant-temperature bath, continuously maintainingthe stirring state, and reacting at a certain temperature; and (3) after the reaction, cooling the reaction liquid to be below 30 DEG C, pouring into water, filtering and drying to obtain the 1-(3-nitry-2-pyridine)-1H-benzotriazole (BP) compound. By the synthesis method, the production cycle of the BP compound can be shortened by 3 to 12 times, the production efficiency is improved, the industrialized production of BPTAP can be promoted, the production cost can be reduced, and industrialization of high-temperature heat-resistant explosive is realized.

Description

technical field [0001] The invention relates to a compound synthesis method, in particular to a highly efficient synthesis method of 1-(3-nitro-2-pyridine)-1H-benzotriazole (BP) compound. Background technique [0002] 1-(3-nitro-2-pyridine)-1H-benzotriazole (BP) is a high-temperature heat-resistant explosive 2,4,8,10-tetranitro-phenylpyridine-1,3a,6,6a- An important intermediate of tetraazapentalpine (BPTAP), and BPTAP is expected to be used in fields such as petroleum perforating bombs and high-energy heat-resistant explosives due to its good thermal stability. The synthesis of BP and its derivatives has been completed in foreign countries in the 1980s. The United States published the synthesis process of BPTAP in 2005, which includes the synthesis process of BP. The reaction needs to be carried out for 24 hours under the reflux of acetonitrile (boiling point: 81.6 ° C), and the reaction time is very long. The researchers of the Xi'an Institute of Modern Chemistry in Chin...

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Problems solved by technology

[0003] At present, with the development of deep well oilfields in China, the demand for high-temperature heat-resistant explosives is also very urgent, and the industrial production of BP compounds as intermediates has not yet formed.