Drug sustained-release implant agent and implanting device thereof

A drug and sustained-release technology, applied in the field of biomedicine, can solve the problems of uncontrollable release concentration, short effective action time, poor stability, etc., achieve significant technical advantages and scientific research value, simple and easy production and use methods, production process uncomplicated effects

Pending Publication Date: 2018-03-06
INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
View PDF0 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the poor stability of oral or injected hormones in animals, the short effective time of action, and the uncontrollable release concentration, it is difficult to fully explore its role in the life process in research
In addition, in the past, due to the limitations of the implantation method, the wounds of the animals were too large during the implantation, which caused infection in mild cases and death in severe cases, resulting in hu...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Drug sustained-release implant agent and implanting device thereof
  • Drug sustained-release implant agent and implanting device thereof
  • Drug sustained-release implant agent and implanting device thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1 Sheep subcutaneous estrogen sustained-release implant and implant device

[0033] Taking sheep estrogen slow-release implantation as an example, refer to figure 1 and figure 2 , are described as follows in conjunction with the examples:

[0034] 1. The subcutaneous estrogen slow-release implant is composed of 17-β estradiol, laboratory grade silicone tube and medical room temperature curing adhesive. Hormone slow release rate.

[0035] 2. If figure 1 As shown in A, the silicone tube used in this example has an inner diameter of 3.5 mm and an outer diameter of 5.5 mm. First, the silicone tube is cut to 2 cm, and one port is sealed with a medical adhesive (type A transparent medical silicone), and the adhesive is solidified. Then put estrogen into the tube, the amount of estrogen in the silicone tube is 2.09±0.18mg / cm 3 , and then close another port to complete the production of estrogen implant ( figure 2 , A-C).

[0036] 3. figure 1 B is a schemat...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Lengthaaaaaaaaaa
Login to view more

Abstract

The invention discloses a drug slow-release implant and an implant device thereof. The drug slow-release implant is in the shape of a capsule and consists of a drug, a laboratory-grade silicone tube and a medical curing adhesive. The drug is placed in the In the silicone tube, the openings at both ends of the silicone tube are sealed with the curing adhesive, and the slow release of the drug is controlled by the micropores on the surface of the silicone tube. The implanting device of the present invention includes a hollow sleeve and a drug pushing needle core, and is used for implanting the drug sustained-release implant in the animal body or subcutaneously. The drug sustained-release implant provided by the invention has the advantages of long sustained-release period and stable release, and the implantation device is simple and easy to manufacture and use, and has significant technical advantages and scientific research value.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a drug sustained-release implant and an implant device. Background technique [0002] Estrogen is a steroid hormone that is mainly secreted by the ovaries. In mammals, estrogen mainly promotes and maintains the development of secondary sexual characteristics before puberty; after sexual maturity, estrogen mainly regulates the physiological activities of female animal hypothalamus, pituitary, ovary, placenta and reproductive tract, etc. It has a huge impact on the reproductive activities of animals. [0003] At present, in the field of life science research, methods such as estrogen implantation are widely used to study its effect on animal reproductive physiological activities. However, due to the poor stability of oral or injected hormones in animals, the short effective time of action, and the uncontrollable release concentration, it is difficult to fully explore its role...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K9/00A61K47/34A61K31/565A61D7/00
CPCA61K47/34A61D7/00A61K9/0024A61K31/565
Inventor 刘秋月储明星贺小云张效生张金龙狄冉王翔宇胡文萍
Owner INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap