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A kind of Paecilomyces coral species and its cultivation method and application

A technology of Paecilomyces and coral, which is applied in the field of microorganisms, can solve the problems such as the absence of Paecilomyces coral species, and achieve the effect of vigorous mycelium growth ability and improved salt and alkali resistance

Active Publication Date: 2021-02-09
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, no Paecilomyces coral species have been found in mainland China

Method used

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  • A kind of Paecilomyces coral species and its cultivation method and application
  • A kind of Paecilomyces coral species and its cultivation method and application
  • A kind of Paecilomyces coral species and its cultivation method and application

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Embodiment 1

[0044] A method for cultivating Paecilomyces corals, comprising the following steps:

[0045] (1) Make the mother seed: sterilize the seeds of Junqianzi that cannot germinate normally in the second year with 75% alcohol for 2-3 times, then cut into small pieces and place them in the sterilized PDA culture dish, and then culture them at 25°C Cultivate in dark at constant temperature in the box for 7 days until the yellow-green mycelium grows to obtain the mother species, and then store it on the slant of the test tube culture medium;

[0046] The comprehensive PDA slope is composed of the following raw materials in proportion by weight: 20% potato, 2% glucose, 2% agar, 0.3% potassium dihydrogen phosphate, 0.15% magnesium sulfate, and the rest is water;

[0047] (2) Solid culture: Take the Paecilomyces corallis strain preserved on the oat slant, take a small piece and connect it to the fresh oat solid slant medium, and then culture it in a constant temperature incubator at 25 °C...

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Abstract

The invention belongs to the technical field of microorganisms, and specifically relates to a Paecilomyces coralii strain and its cultivation method and application. Silk growth ability, rich in protein, quinalizarin, inorganic salts and various polysaccharides, plays an important role in the health care and pharmaceutical industries, and brings new gospel to patients with tumors and depression; the strains cultivated in the present invention Improved salt and alkali resistance.

Description

technical field [0001] The invention belongs to the technical field of microorganisms, and in particular relates to a Paecilomyces coral species and a cultivation method and application thereof. Background technique [0002] Paecilomyces coralii was first discovered by Solms-Laubach and Reink in 1887, and it is widely found on persimmons in tropical areas such as Indonesia. Collected in Taiwan Province of China pesudo cordyceps semiminicola Ascospores were found on naturally growing mature spores. Penicilliopsis clavariaeformis Metabolites obtained by crystallization and purification of AP penicilliopsin , is an orange-yellow pigment substance, which is isolated and extracted to obtain quinalizarin (skyrin (dediemodin (8,8')) or emodin ( emodin ). Skyrin and emodin Has antidepressant or antitumor activity. In recent years, lead compounds with antidepressant and antitumor effects have been a hot spot for drug workers at home and abroad. The most ideal source of act...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/14A61K36/062A61P25/24A61P35/00C12R1/645
CPCA61K36/062C12N1/14C12N1/145C12R2001/645
Inventor 徐凌川陈文华李学飞王昊冉盛可心
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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