Anti-fatigue compound preparation, and preparation method and anti-fatigue application thereof

A compound preparation and anti-fatigue technology, which is applied in the field of biotechnology medicinal and edible plants, can solve the problems of slow onset of action, and achieve the effect of increasing reserves, large health care and clinical application value, and small dosage

Inactive Publication Date: 2018-03-27
南京御匾国健生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing anti-fatigue preparations are mainly traditional Chinese medicines, which are characterized by health preservation. Consumers need to take them for a long time, and the effect is slow

Method used

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  • Anti-fatigue compound preparation, and preparation method and anti-fatigue application thereof
  • Anti-fatigue compound preparation, and preparation method and anti-fatigue application thereof
  • Anti-fatigue compound preparation, and preparation method and anti-fatigue application thereof

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Experimental program
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Effect test

Embodiment 1

[0059] 1 Materials and methods

[0060] 1.1 Sample:

[0061] 1.2 Experimental animals: five-month-old middle-aged male ICR mice; eight-month-old old male C57 mice.

[0062] 1.3 Instruments and reagents: swimming box, lead wire, full-wavelength microplate reader, constant temperature water bath, centrifuge, liver

[0063] Glycogen Detection Kit (Nanjing Jiancheng, Cat. No. A043), Lactic Acid Detection Kit (Nanjing Jiancheng, Cat. No. A019-1), Urea Nitrogen Kit (Nanjing Jiancheng, Cat. A001-1), MDA detection kit (Nanjing Jiancheng, article number A003-1).

[0064] 1.4 Experimental method:

[0065] A. The first batch: 60 male five-month-old middle-aged ICR mice were randomly divided into 4 groups, 15 in each group. The low-dose group received 100 mg / kg intraperitoneal injection, the middle-dose 300 mg / kg intraperitoneal injection, and the high-dose 900 mg / kg intraperitoneal injection. The control group was given the same volume of normal saline. Administer once a day from 1...

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Abstract

The invention discloses an anti-fatigue compound preparation, and a preparation method and anti-fatigue application thereof. Experimental results show that the compound preparation is capable of prolonging the loaded swimming time of middle-age and old mice, increasing the reservation of hepatic glycogen and reducing the contents of lactic acid and urea nitrogen through combined usage of natto andhorseradish tree leaves, and the effect of the combined usage of natto and horseradish tree leaves is obviously better than the effect of separate usage of natto and horseradish tree leaves. Moreover, the anti-fatigue compound preparation has the advantages of small dosage, safety, administration in both injecting and oral ways, etc., and has great health-care and clinic application value. The anti-fatigue compound preparation can be used for preparation of anti-fatigue health products or foodstuffs.

Description

technical field [0001] The invention relates to the field of biotechnology medicinal and edible plants, in particular to an anti-fatigue preparation, a preparation method thereof and an anti-fatigue application. Background technique [0002] Fatigue is a subjective sense of discomfort, mainly manifested as fatigue and burnout, which can be noticed during long-term labor, strenuous exercise or long-term mental stress. This is a normal physiological protective response, suggesting that the body should Rest to restore function and avoid further damage to the body. However, with the intensification of social competition and the acceleration of the pace of life, people often choose to work long hours regardless of fatigue. Being in a state of fatigue for a long time will damage the physical strength and fitness of the human body, and the body will be out of balance, making it difficult for people to engage in or complete some jobs that consume a lot of energy or have delicate an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P39/00A23L11/00A23L33/00A23L11/50
CPCA61K36/185A61K36/48A23V2002/00A61K2300/00A23V2200/30A23V2250/21
Inventor 范盘生路三江
Owner 南京御匾国健生物科技有限公司
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