Clarifying process and quality control method of medicinal composition with function of treating dark eye circles
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A quality control method, a technology for dark circles, applied in the direction of drug combination, medical preparation containing active ingredients, pharmaceutical formula, etc.
Inactive Publication Date: 2018-04-03
GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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At present, there are no relevant reports at home and abroad that the composition of Baihuabaicang, Liuyueqing, Maodongqing, Sperantospermia, Centella asiatica, Tianshan Snow Lotus, Golden Ear and Airplane Grass is used to treat dark circles
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[0056] A clarification process and quality control method of a pharmaceutical composition with the effect of treating dark circles of the present invention, the clarification process is carried out as follows:
[0057] Clarification process and content of each component
[0058] (1) Preparation of clarifying agent: Type II ZTCl+1 natural clarifying agent consists of two components, A and B. Component A: Precisely measure 1.0g of component A, add a small amount of distilled water, stir to form a paste, then add distilled water to prepare 100mL of viscose, swell for 24 hours, and filter with double gauze. Component B: Precisely measure 1.0g of component B, add a small amount of 1% acetic acid solution by volume, stir to form a paste, then add 1% acetic acid solution to make 100mL viscose solution, swell for 24 hours, Filter with double gauze, that is, too.
[0059] (2) Adding order of clarifiers A and B: According to the instructions, ZTC natural clarifier mainly chooses diffe...
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Abstract
The invention discloses a clarifying process and a quality control method of a medicinal composition with the function of treating dark eye circles. The medicine is composed of 8 medicinal materials including herba patrima villosa, stems and leaves of Goldfussia psilostachys (C.B.Clarke ex W. W. Smith) Bremek.[Strobilanthes psilostachys C.B.Clarke ex W.W Smith], radix ilicis pubescentis, herba speranskiae tuberculatae, herba centellae, herba saussureae involucratae, herba carpesii divaricati and herba eupatorii odorati. For the specific clarifying process, a II type ZTC 1+1 natural clarifyingagent is adopted for clarifying an extracting solution of the medicinal composition; for the specific quality control method, thin-layer identification is carried out on stems and leaves of Goldfussiapsilostachys (C.B.Clarke ex W. W. Smith) Bremek.[Strobilanthes psilostachys C.B.Clarke ex W.W Smith], herba speranskiae tuberculatae and herba saussureae involucratae, meanwhile, the contents of villosol, ilexsaponin B, asiaticoside, carabrone and apigenin in the medicinal composition are measured by adopting a high performance liquid chromatography method. The clarifying process and the qualitycontrol method adopted by the invention have the advantages that the equipment investment is small, the operation process is simple, the defects that in the traditional alcohol precipitation method, the alcohol consumption amount is large, the alcohol recovery is complicated, the measurement for various ingredients of the medicine is complicated, etc., are overcome, the inherent quality, curativeeffects and stability of the composition are quickly and effectively guaranteed, and the controllability of the quality standard of the medicinal composition is improved.
Description
technical field [0001] The present invention adopts a clarification process using a natural clarifier and a modern analysis and detection instrument to detect traditional Chinese medicine preparations. The technical field relates to a clarification process quality control method for a pharmaceutical composition with the effect of treating dark circles. Background technique [0002] The skin around the eyes is the thinnest, and the melanin activity is very strong. Coupled with aging, external stimuli and other factors, various problems are prone to occur, and the appearance of dark circles is inevitable! The so-called dark circles are when the blood flow in the veins of the eyes is too slow, the supply of red blood cells in the skin of the eyes is insufficient, and the carbon dioxide and metabolic wastes in the veins accumulate too much, forming chronic hypoxia, darker blood and formation of stagnant and dark circles around the eyes. Hyperpigmentation A bluish-blue or dark br...
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