Focus domain control method based on 256-element hemispherical phased array ultrasonic transducer

An ultrasonic transducer, hemispherical technology, applied in ultrasonic therapy, treatment and other directions, can solve the problems such as no research, no clear transcranial safe treatment range of hemispherical transducers, etc. Cranial focusing performance, the effect of expanding the safe and treatable range of transcranial

CN107913476BActive Publication Date: 2019-06-18TIANJIN MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2019-06-18

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Abstract

The invention discloses a focal region regulation and control method of a semispherical phased array ultrasonic energy transducer based on 256 array elements. The focal region regulation and control method of the semispherical phased array ultrasonic energy transducer based on 256 array elements includes the following steps: S1, randomly designing the center coordinate position of the first arrayelement; S2, when the center distance between neighboring array elements is no less than 18mm, selecting the nearest array element as the center coordinate position of the next array element, and according to the above steps, successively designing other array elements until the number of the array elements is 256; S3, exciting all the 256 array elements to realize transcranial focusing, performing value simulation on the temperature fields which are formed in the x, y and z directions of the three dimensional space, and determining the safe regulable and controllable range of the energy transducer; and S4, selecting part of the array elements of the energy transducer to excite to enlarge the safe regulable and controllable range of the energy transducer. The focal region regulation and control method of the semispherical phased array ultrasonic energy transducer based on 256 array elements can avoid occurrence of skull scald during the treating process of transcranial neurological disease, can realize focusing of small-opening non semispherical energy transducer in the large opening semispherical energy transducer, can enlarge the focal region regulation and control range, and canimprove the transcranial focusing performance of the energy transducer.
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Description

technical field

[0001] The invention relates to the technical field of high-intensity focused ultrasound, in particular to a focal region control method based on a 256-element hemispherical phased array ultrasonic transducer. Background technique

[0002] Brain tumor is one of the diseases of the brain and nervous system, and has become a major disease that endangers human life and health. Conventional surgical resection, radiotherapy, and chemical drug therapy have high risks, large side effects, and large Molecular drugs cannot enter the brain tissue and other deficiencies, and neurological diseases such as epilepsy, neuralgia and tremor also have the risk of surgery, and high-intensity focused ultrasound (HIFU) with the characteristics of non-invasive and repeatable treatment is a One of the promising technologies for the clinical treatment of brain and nervous system diseases. In the process of HIFU transcranial treatment of these diseases, due to the large difference i...

Examples

Embodiment 1

[0052] S1: According to the formula (1) θ(i)=π·rand(1,1), (2) on the rigid hemisphere (3) (4) and (5) z(i)=R o · cos(θ(i)) randomly generates the coordinate position (2.07, 125.75, 144.64) of the center of the first array element.

[0053] S2: Under the condition that the distance between the centers of adjacent array elements is not less than 18mm, select the nearest array element as the center coordinate position of the next array element, and then generate other array elements sequentially according to the above formulas (1)-(5) until the number of array elements for 256, figure 1 It is a schematic structural diagram of a 256-element hemispherical phased array ultrasonic transducer.

[0054] S3: All 256 array elements of the excitation transducer are focused transcranially, and the excitation signal is formula (6) Under the condition that the excitation frequency is 0.7MHz, the input power is 50W, and the irradiation time is 10s, the temperature field formed in the...

Embodiment 2

[0063] The method for controlling the focal region of all array elements based on the 256-element hemispherical phased array ultrasonic transducer is the same as that of Example 1 to implement steps S1-S3. The implementation steps of the focal region control method for some array elements are as follows:

[0064] S4: Select 12 excitation array elements close to the center of the substrate in the four quadrants of the transducer. The serial numbers of the array elements are shown in Table 2. Under the condition of input power of 60W, the excitation signal is formula (7) Regulates the safe focus range of the transducer.

[0065] The numbers of the 48 excitation elements selected in Table 2

[0066]

[0067] Figure 10 It is the temperature distribution of the transcranial focus at (144, 150, 150) and (138, 150, 150) along the acoustic axis of the 48 array elements that excite the 256-element hemispherical phased transducer and its acoustic axis temperature distribution cur...