Hemodialysis concentrate

A technology for hemodialysis and concentrate, applied in the field of hemodialysis, can solve the problems of inconvenience and time-consuming on the user side

Inactive Publication Date: 2018-05-25
济泰(上海)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Patients will use two kinds of hemodialysis fluid during the dialysis process, which are acid concentrated solution (referred to as liquid A) and bicarbonate concentrated solution (referred to as liquid B). Before use, liquid A and liquid B must be connected to the kidney dialysis machine , the kidney dialysis machine is diluted with dialysis water in proportion to obtain the final dialysis solution for patients to use; the sugar-free solution A is commonly used in hospitals (refer to the label of Ziwei Mountain in Appendix 2), and the dilution ratio is A solution: B Solution: water for dialysis = 1:1.225:32.775, but the current commercially available sugar-containing A solution has a dilution ratio of A solution: B solution: dialysis water = 1:1.26:32.74, which is different from the ratio used in sugar-free A solution. If you want to use sugar-containing liquid A, you need to adjust the settings of the kidney dialysis machine, and the user must also monitor the concentration of each ion (the control of ion concentration is very important for dialysis) to see if it is the same as the design, so if you want to use Sugar-containing liquid A, it must take time to confirm whether the dilution ratio is correct, which is inconvenient and time-consuming for the user

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1) According to the content of each component of liquid A, weigh sodium chloride, potassium chloride, calcium chloride, magnesium chloride, glucose (containing a molecule of crystal water) and glacial acetic acid, add an appropriate amount of dialysis water to completely dissolve, mix and stir evenly;

[0018] 2) According to the content of each component of liquid B, weigh sodium bicarbonate, add an appropriate amount of dialysis water to completely dissolve, mix and stir evenly;

[0019] 3) Fill the well-stirred liquid A and liquid B into the plastic bucket and lock the lid.

[0020] As a preferred technical solution, the dilution ratio of the obtained hemodialysis concentrated solution A, bicarbonate concentrated solution B and dialysis water is 1:1.225:32.775, and it needs to be used together with a dialysis machine, and the mixed solution after absorbing in proportion In the sodium ion concentration 138mmol / L, potassium ion 2mmol / L, calcium ion concentration 1.5mmo...

Embodiment 2

[0022] 1) According to the content of each component of liquid A, weigh 208.0g / L sodium chloride, 5.0g / L potassium chloride, 6.0g / L calcium chloride, 3.5g / L magnesium chloride, 7.0g / L glacial acetic acid and 35.0g / L glucose (including one molecule of crystal water), add an appropriate amount of dialysis water to completely dissolve, mix and stir evenly;

[0023] 2) According to the content of each component of liquid B, weigh 82.0g / L sodium bicarbonate, add an appropriate amount of dialysis water to completely dissolve, mix and stir evenly;

[0024] 3) Fill the well-stirred liquid A and liquid B into the plastic bucket and lock the lid.

[0025] As a preferred technical solution, the dilution ratio of the obtained hemodialysis concentrated solution A to the bicarbonate concentrated solution B and dialysis water is 1:1.225:32.775, and it needs to be used together with a dialysis machine.

Embodiment 3

[0027] 1) According to the content of each component of liquid A, weigh 212.0g / L sodium chloride, 5.5g / L potassium chloride, 8.0g / L calcium chloride, 4.0g / L magnesium chloride, 11.5g / L glacial acetic acid and 82.0g / L glucose (including one molecule of crystal water), add an appropriate amount of dialysis water to completely dissolve, mix and stir evenly;

[0028] 2) According to the content of each component of liquid B, weigh 86.0g / L sodium bicarbonate, add an appropriate amount of dialysis water to completely dissolve, mix and stir evenly;

[0029] 3) Fill the well-stirred liquid A and liquid B into the plastic bucket and lock the lid.

[0030] As a preferred technical solution, the dilution ratio of the obtained hemodialysis concentrated solution A to the bicarbonate concentrated solution B and dialysis water is 1:1.225:32.775, and it needs to be used together with a dialysis machine.

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Abstract

The invention discloses hemodialysis concentrate. The hemodialysis concentrate comprises a hemodialysis concentrated solution A and a hemodialysis concentrated solution B and is prepared from 208.0-212.0 g / L sodium chloride, 5.0-5.5 g / L potassium chloride, 6.0-8.0 g / L calcium chloride, 3.5-4.0g / L magnesium chloride, 7.0-11.5 g / L glacial acetic acid, 82.0-86.0 g / L sodium bicarbonate and 35.0-41.0 g / L or 70.0-82.0 g / L glucose (containing one molecule of crystal water). The hemodialysis concentrate needs to be used in cooperation with a dialysis machine, and is prepared from the hemodialysis concentrated solution A, the hemodialysis concentrated solution B and dialysis water at a dilution ratio of 1:1.225:32.775. The hemodialysis concentrate provides a better choice for patients suffering from hypoglycemia dialysis, the steps are simplified, the working efficiency is improved, and the operation is easy and convenient.

Description

technical field [0001] The present invention relates to the technical field of hemodialysis, more specifically, to a hemodialysis concentrate. Background technique [0002] During the dialysis process of hemodialysis patients, the glucose in the body will be filtered out of the body through the dialyzer and the blood sugar will gradually decrease. [0003] Patients will use two kinds of hemodialysis fluids during dialysis, namely acid concentrate (referred to as A solution) and bicarbonate concentrate (referred to as B solution). Before use, both A and B must be connected to the dialysis machine. , the dialysis machine is diluted with dialysis water in proportion to obtain the final dialysis solution for patients to use; the hospital commonly used sugar-free A solution (refer to the label of Lagerstroemia in Annex 2), and its dilution ratio is A solution: B Solution: water for dialysis = 1:1.225:32.775, but the current commercially available sugar-containing solution A has ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/14A61K9/08A61P7/08A61K31/19A61K31/7004A61K33/00A61K33/06
CPCA61K9/0026A61K9/08A61K31/19A61K31/7004A61K33/00A61K33/06A61K33/14A61K2300/00
Inventor 魏丽珠
Owner 济泰(上海)生物科技有限公司
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