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Pharmaceutical composition for treating diabetes mellitus as well as preparation method and use of pharmaceutical composition

A composition and technology for diabetes, applied in the field of traditional Chinese medicine, can solve hidden diabetes associated with abnormal sweating (Dang Zhimin, etc., hidden diabetes associated with abnormal sweating, endangering health and lifespan, recovery of complications, etc. problems, to achieve no toxic side effects, improve symptoms, lower blood sugar levels

Inactive Publication Date: 2018-06-08
北京睿悦生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Only 25% of domestic diabetic patients can find out that they have diabetes, and as many as 75% of patients do not know the disease. Complications and poor prognosis of vital organs such as the kidneys, which endanger health and life expectancy
[0005] It has been reported in the literature that patients with hidden diabetes did not take corresponding hypoglycemic measures after surgery, resulting in postoperative infection of lumbar disc herniation (Li Shuying, et al., Case analysis of postoperative infection of lumbar disc herniation caused by hidden diabetes, Journal of Chengde Medical College, Vol.30No.2 2013); Facial paralysis associated with recessive diabetes (Huang Di, et al., Clinical analysis of facial paralysis associated with recessive diabetes, Hebei Medicine, Volume 33, Issue 23, December 2011); Abnormal sweating (Dang Zhimin et al., Abnormal sweating associated with recessive diabetes, Journal of Brain and Nervous Diseases, Volume 14, No. 3, 2006); most of the drugs reported are for the treatment of diabetes, and for the treatment of recessive diabetes, there are still Medications for which there is no specific treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0031] 1. Raw materials: Radix Astragalus 15g, chickpea 10g, kudzu root 10g, tangerine peel 10g, the dose is the daily dose.

[0032] 2. Preparation method: take the crude drug according to the above weight ratio;

[0033] Put the cleaned chickpeas into a container, add 5 times of deionized water, soak for 6 hours; germination time for 12 hours; add 4-5 times of deionized water for germinated chickpeas and use a colloid mill Refining, adding acetic acid (concentration of acetic acid is 0.9%), controlling the temperature at 10°C, and stirring for 8 hours; filtering, collecting the filtrate by filtration with a 1500D organic membrane, and then filtering with a 6000D organic membrane, and taking the filtrate for freeze-drying or spray-drying Chickpea extract 1 was prepared.

[0034] Add 10-15 times of water to decoct Radix Astragali, Radix Puerariae, and Tangerine Peel twice, take the d...

Embodiment 2

[0035] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0036] 1. Raw materials: Sun-roasted astragalus 20g, chickpeas 15g, kudzu root 20g, tangerine peel 15g.

[0037] 2. Preparation method: extract according to the method of Example 1, mix the extracts, add starch to granulate, granulate, and compress into tablets to obtain tablets.

Embodiment 3

[0038] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0039] 1. Raw materials: Sun-roasted astragalus 10g, chickpeas 5g, kudzu root 10g, tangerine peel 10g.

[0040] 2. Preparation method: the extract prepared by the method in Example 1 is prepared into granules.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating diabetes mellitus as well as a preparation method and use of pharmaceutical composition, belonging to the field of traditional Chinesemedicine. The pharmaceutical composition contains the following raw material drugs in parts by weight: 10-20 parts of radix astragali, 5-15 parts of chickpeas, 5-20 parts of radix puerariae and 3-15parts of pericarpium citri reticulatae. The invention further provides the preparation method and use of the pharmaceutical composition. According to the pharmaceutical composition, the blood glucoselevel can be obviously lowered, the insulin level is relatively close to a normal range, and the pharmaceutical composition can be utilizing for improving the symptoms of patients with diabetes mellitus and effectively treating diabetes mellitus; and particularly, a reasonable compatible set prescription of the pharmaceutical composition is used for treating latent diabetes mellitus, has an obvious treatment effect, does not have toxic and side effects and has a relatively high clinical application value.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating diabetes, a preparation method and application thereof. Background technique [0002] Diabetes is the third major disease that threatens human life. With the development of China's economy, people's lifestyles have changed, and the incidence of diabetes is also increasing year by year. It is the most common metabolic disease. It is insulin secretion defect, manifested as high blood sugar, which will affect the patient's heart and kidneys in the later stage, causing a variety of chronic diseases in the patient, and in severe cases, a variety of complications will appear, affecting the quality of life of the patient. [0003] Latent diabetes, also known as impaired glucose tolerance, is a metabolic state between normal blood sugar and diabetes. Because there are no typical symptoms of overt diabetes, "three highs and ...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P3/10
CPCA61K36/48A61K36/481A61K36/488A61K36/752A61K2236/331A61K2236/333A61K2236/35A61K2236/39A61K2300/00
Inventor 王文娟张连成郭稼付冀峰
Owner 北京睿悦生物医药科技有限公司
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