Rhubarb ultramicro powder-containing film spraying agent for traumatic wounds and preparation method thereof

Abstract

The invention discloses a rhubarb ultramicro powder-containing film spraying agent for traumatic wounds and a preparation method thereof. Specifically, the rhubarb ultramicro powder-containing film spraying agent for traumatic wounds adopts rhubarb made into ultramicro powder as the raw material, the prepared rhubarb ultramicro powder has a particle size of 75microm or below. The preparation method of the rhubarb ultramicro powder-containing film spraying agent for traumatic wounds includes the following process steps: (1) subjecting rhubarb herb material to preliminary crushing to obtain rhubarb crude powder, then conducting ultramicro pulverization on the rhubarb crude powder to obtain rhubarb ultramicro powder; (2) dissolving chitosan hydrochloride in deionized water, adding a modifier, and performing stirring till complete dissolution; (3) dissolving povidone K30 in anhydrous ethanol, then adding the rhubarb ultramicro powder obtained in step (1), and mixing the substances evenly;and (4) mixing the solution obtained in step (2) and the solution obtained in step (3) to obtain the rhubarb ultramicro powder-containing film spraying agent for traumatic wounds. The rhubarb ultramicro powder-containing film spraying agent for traumatic wounds provided by the invention can effectively treat various skin injured traumas, and has the characteristics of protecting wounds, absorbingwound exuded liquid, promoting tissue repair and regeneration, accelerating wound healing and the like.

Description

Technical field: [0001] The invention belongs to the field of medical devices, and in particular relates to a film-spraying agent for traumatic wounds containing rhubarb superfine powder and a preparation method thereof. Background technique: [0002] Skin damage trauma caused by bruises and other causes in daily life is inevitable. If these traumas are not handled properly, they may cause wound suppuration and persistent wounds. In severe cases, life-threatening symptoms such as systemic infection may occur. Therefore, from ancient times to the present, the treatment of skin lesion trauma is very important. Currently, there are many drugs on the market for treating blunt trauma, such as various medicated wines, aerosols, etc.; there are fewer drugs for treating skin trauma, because skin trauma has higher requirements for drugs and dosage forms. Require. Skin lesion trauma, especially when the wound surface is large, without the protection of the epidermis, the preparation...

AI Technical Summary

Problems solved by technology

For example, the application numbers CN201310561642.4 and CN201110319221.1 respectively disclose a preparation method of a spray film agent for stretching tendons and activating blood circulation and a film spray agent for treating acute soft tissue injuries and a preparation method thereof. The film spray agents described in these two patents are mainly It is used for anti-inflammatory and analgesic of closed wounds, but not for the treatment of skin lesion wounds; the application numbers are CN201310507476.X (Houttuynia scald spray film and its preparation method), CN94116292.3 (wounds for the treatment of wounds and skin diseases) Fuling spray film) and the spray film described in CN201310090894.3 (a dragon's blood spray film applied to superficial trauma and its preparation process), which can be used for skin lesion burns, sassafras scratches, etc. Wounds, but because the extracts of Chinese medicinal materials are used as medicine, the powder can not absorb the wound exudate and keep the wound dry. Treatment of wounds with large area and fluid exudation

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