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A kind of hair follicle preservation solution and preparation method thereof

A technology of preservation solution and hair follicles, which is applied in the medical field, can solve the problems of short storage time, large limitations of hair follicles, unfavorable development of hair follicle units, etc., and achieve the effect of preventing damage, preventing swelling between cells, and prolonging the survival time in vitro

Active Publication Date: 2021-08-27
张长水
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The number of hair follicle transplants is increasing and the operation time is getting longer and longer. However, in the current clinical work, the hair follicles are still stored in normal saline or low-temperature saline after they are isolated. Surgery required
This method of hair follicle preservation is limited and the preservation time is short (not more than 6 hours in clinical practice), which is not conducive to the development of a large number of hair follicle unit transplants (currently the number of hair follicle transplants often exceeds 3000FU, and the operation time exceeds 6 hours), which is not conducive to transplantation Increased postoperative survival rate

Method used

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  • A kind of hair follicle preservation solution and preparation method thereof
  • A kind of hair follicle preservation solution and preparation method thereof
  • A kind of hair follicle preservation solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Basic program:

[0056]

[0057]

[0058] The above solute is formulated with water (distilled water) for the solvent to formulate the total volume: 1000 mL; pH: 7.0 ± 0.2; osmotic pressure: 310mmol / l ± 20 mmol / L; application temperature is 4-8 degrees Celsius; formula is sterilized class.

[0059] Advantages: economy, effective, feasible.

[0060] Disadvantages: high sugar, high chlorine.

Embodiment 2

[0062] 甲 方案:

[0063]

[0064] The above solute is formulated into total volume: 1000 mL; pH value: 7.0 ± 0.2; osmotic pressure: 310mmol / L ± 20 mmol / L; Formulation liquid is 4-8 degrees Celsius; Sterilization

[0065]Advantages: effective, feasible, no chlorine.

[0066] Disadvantages: High sugar.

Embodiment 3

[0068] B type generation:

[0069]

[0070] The above solute is formulated into total volume: 1000 mL; pH value: 7.0 ± 0.2; osmotic pressure: 310mmol / L ± 20 mmol / L; Formulation liquid is 4-8 degrees Celsius; Sterilization of medical level.

[0071] Advantages: effective, feasible, good effect.

[0072] Disadvantages: High sugar and economic cost is high.

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Abstract

The invention discloses a hair follicle preservation solution and a preparation method thereof, comprising the steps of: 1) taking 20-40 g of succinylated gelatin, 100-120 mmol of potassium salt, 20-50 mmol of potassium dihydrogen phosphate, 0-12 mmol of sodium hydroxide, 0-1 60mmol sugar, 5-10mg vitamin B2, 50-100mg vitamin B6, 1-3g vitamin C as solute; 2) Add the above solute into distilled water to make a solvent with a total volume of 1000mL; 3) Sterilize the above solvent to reach medical grade The hair follicle preservation solution is obtained; the preservation solution of the present invention can obviously prolong the in vitro survival time of hair follicles, and provides scientific and effective technical support for a large number of hair transplantation.

Description

Technical field [0001] The present invention relates to the field of medical technology, and more particularly to a hair follicle preservation solution and a preparation method thereof. Background technique [0002] In 1897, human beings successfully transplanted scalp tissue into trauma, which were identified as the initial hair follicle transplantation. Since this hair transplantation has experienced the process of transplanting the flap to a single hair follicle transplantation, there has been a lot of progress during the period. The number of hair follicles is growing and more long, but the hair follicle is still placed in physiological saline or low-temperature saline after the hair follicle in the clinical work, and the preservation concept is still staying in the skin transplantation. It is no longer able to meet the current clinical practice. Surgical needs. This method stores the lamination of the hair follicle and the preservation time is short (not more than 6 hours in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N1/02
CPCA01N1/0226
Inventor 张长水
Owner 张长水