Medicine for treating leukopenia after radiotherapy and chemotherapy, preparation method and application thereof

A technology of radiotherapy, chemotherapy and leukocytes, which is applied in the fields of medicine, pharmacy and tumor treatment, can solve the problems of ineffective Chinese patent medicines, stomatitis, and poor compliance, and achieve the effects of improving compliance, improving acceptance, and improving inclusion

Active Publication Date: 2020-10-09
华佑众生(北京)医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This imposes great limitations on its application
[0012] While researching modern medical treatment methods and discovering its limitations, the inventor also conducted research in combination with the traditional medicine of the motherland. We found that many Chinese patent medicines that increase white blood cells have no obvious effect and slow onset, and some patients have oral cavity after taking the medicine. Inflammation, poor compliance

Method used

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  • Medicine for treating leukopenia after radiotherapy and chemotherapy, preparation method and application thereof
  • Medicine for treating leukopenia after radiotherapy and chemotherapy, preparation method and application thereof
  • Medicine for treating leukopenia after radiotherapy and chemotherapy, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] Embodiment 1 Granule preparation of the present invention

[0072] Weigh the raw material particles (kg) according to the following ratio

[0073] Henan Shudi 70, Sichuan Ophiopogon japonicus 20, Yunnan Poria cocos 15, and Guangdong cinnamon 10.

[0074] The production method is as follows: wash the raw medicinal materials to remove impurities; take rehmannia glutinosa, freeze-dry and pulverize them at -15°C, and pass them into 200-mesh fine powders; The water decoction is collected, mixed evenly, kept at 110°C for 10 minutes, then cooled to 105°C for 5 minutes, then cooled to 100°C for 15 minutes, aged and sterilized to obtain granules. Oral 10 grams each time, 2 times a day, take it with warm water.

Embodiment 2

[0075] Embodiment 2 Granule preparation of the present invention

[0076] Weigh the particles according to the following ratio (kg)

[0077] Henan Shudi 72 Sichuan Ophiopogon japonicus 23 Yunnan Poria cocos 12 Guangdong cinnamon 8

[0078] Production method refers to embodiment 1.

Embodiment 3

[0080] In order to show that the medicine of the present invention has a therapeutic effect on the leukopenia caused by radiotherapy and chemotherapy, from October 2009 to February 2011, comparatively observed the oral administration of medicines (20 examples) and the use of Shengxue Pills (Tianjin Produced by Darentang Jingwanhong Pharmaceutical Co., Ltd., it consists of velvet antler, Phellodendron cortex, yam, fried Atractylodes macrocephala, mulberry branches, fried white lentils, rice buds, and Ziheche) for treatment (20 cases). Check the venous blood leukocyte level within 1 week after chemotherapy (2.0-4.0)×10 9 / L, or neutrophils in (1.0-2.0)×10 9 / L. The chemotherapy used this time does not contain carboplatin, anthracyclines and other drugs that may cause late myelosuppression. The two groups were comparable in terms of disease types (lung cancer, breast cancer, gastric cancer, colon cancer, ovarian cancer), age, sex and chemotherapy regimen.

[0081] The oral admi...

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Abstract

The invention relates to a medicine for treating a low leucocyte amount after chemoradiotherapy and a preparation method of the medicine, in particular to a traditional Chinese medicine composition for treating a low leucocyte amount after chemoradiotherapy through orally taken traditional Chinese herbal medicines. The medicine is prepared from the following raw materials in parts by weight: 0.60-0.75 part of processed rehmannia roots, 0.20-0.25 part of radix ophiopogonis, 0.05-0.15 part of poria cocos and 0.05-0.10 part of cortex cinnamomi. The medicine provided by the invention is sufficientin medicinal sources, and the components are all recorded in pharmacopeia. The medicine provided by the invention is capable of treating low leucocyte amount caused by chemoradiotherapy and preventing low leucocyte amounts caused by chemoradiotherapy, is prepared from medicines as both medicines and foods, is safe to take, is capable of greatly improving intaking of patients, has the effect of stopping vomiting, and meanwhile can effectively improve the appetite and thus improve the living quality of patients.

Description

technical field [0001] The present invention relates to the fields of medicine and pharmacy, specifically to the field of tumor treatment, and more specifically to a drug with high safety and good compliance, which can effectively reduce the side effects of leukopenia caused by radiotherapy and chemotherapy in tumor treatment. Chinese medicine composition. Background technique [0002] Tumor, also known as cancer, is a new organism formed when a certain cell in a local tissue loses normal regulation of its growth at the gene level under the action of various tumorigenic factors inside and outside the body, resulting in abnormal clonal proliferation. localized mass. It is estimated that there will be 4.292 million new cases of invasive cancer in my country in 2015, equivalent to an average of 12,000 new cases of cancer every day; there will be 2.814 million cancer deaths, equivalent to an average of 7,500 people dying of cancer every day. Almost 22% of new cancer cases worl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P35/00A61P1/08A61P7/00A61P1/14
CPCA61K36/076A61K36/54A61K36/804A61K36/8968A61K2236/15A61K2236/17A61K2236/331A61P1/08A61P1/14A61P7/00A61P35/00A61K2300/00
Inventor 黄金昶黄梓滢
Owner 华佑众生(北京)医疗科技有限公司
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