A kind of preparation method of 2-pyrrolidone compounds
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- NINGBO UNIV
- Publication Date
- 2021-02-02
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Abstract
Description
technical field
[0001] The application belongs to the field of organic synthesis methodology, in particular to a preparation method of 2-pyrrolidone compounds. Background technique
[0002] 2-Pyrrolidone compounds are a class of pyrrolidine compounds with a five-membered lactam ring, which widely exist in natural products and various synthetic compounds, and are also widely used because of their various biological activities. In the field of medicine, the following formula 1 lists a variety of biologically active compounds containing 2-pyrrolidone compounds that have been disclosed and used in the prior art.
[0003]
[0004] Due to the rich biological activity of 2-pyrrolidone compounds, the development of efficient synthetic methods for this building block is one of the focuses of synthetic chemists, and the most common methods for obtaining 2-pyrrolidone core structures usually rely on the prior formation of Ring expansion or contraction of a ring, cyclization between...