Microfluidics preparation technology for monodisperse gold nanoparticles with controllable size

Abstract

The invention discloses a microfluidics preparation technology for monodisperse gold nanoparticles with controllable size. The microfluidics preparation technology comprises a micro-reaction system constructed based on a gold particle preparation method, the acquisition and transfer of gold nanoparticle reaction precursor liquid, the continuous controllable preparation of the gold nanoparticles and the acquisition of an uniform monodisperse gold nanoparticles toluene solution. According to the microfluidics preparation technology, a complete and simple micro-reaction device is constructed based on the matching mode of a micro-flow continuous pump and a micro-flow control chip, and accurate and controllable high-throughput preparation of the final size, morphology, monodispersity and othercharacteristics of noble metal nanoparticles is realized.

Description

technical field [0001] The invention belongs to the combined field of material science and mechanical automation, and further relates to a microfluidic preparation technology of size-controllable monodisperse gold nanoparticles combined with mechanical automation technology in the field of nanomaterial preparation technology. The invention can be used for high-throughput preparation of monodisperse gold nanoparticles. Background technique [0002] Today, with the vigorous development of nanotechnology, the study of noble metal nanoparticles has always been an important research direction in material science. Its unique physical and chemical properties have attracted extensive attention and in-depth research in many application fields such as biomedicine and aerospace. In order to realize the high-quality application performance of noble metal nanoparticles, it is first necessary to ensure that the prepared nanoparticles have uniform morphology and size, that is, good monodis...

AI Technical Summary

Problems solved by technology

The disadvantages of this patented technology are: firstly, the chip configuration is complex, and it is not easy to design and process; secondly, this patent only uses the special structure of the device to solve the problems of uniform mixing of solutions and anti-blocking of the chip, which will reduce the problem to a certain extent. The process of the chip is convenient

The disadvantages of this patented technology are: the miniature metal pipe has limitations in practical application, although it is resistant to high temperature, its corrosion resistance is relatively poor; moreover, the flexibility of the miniature metal pipe is not high, and its volume occupies the whole part of the device. large, and the flow mixing mode is single; and there are certain problems in the design of the right-angle transition of the micro metal pipe, the fluid will generate local stress at the right-angle transition, and the flow stability will be reduced, which is not conducive to the preparation of nanoparticles. Accurate and controllable

The shortcomings of this patented technology are: firstly, in terms of its geometric configuration design, there may be problems of fit and sealing in the design of the liquid inlet pipe and the inner pipe, which will directly affect the stability and reliability of the microfluidic device Secondly, during the reaction process, the diameter of the front port of the device (10 microns in diameter) is too small to easily block; finally, based on the configuration design of the reaction device, in the micro-droplet flow mode, the organic phase liquid is used as the second phase Auxiliary liquid consumption is large, economical and environmental protection are not high

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