Chitosan derivative colloidal solution

A technology of chitosan derivatives and body fluids, applied in the directions of drug delivery, application, medical science, etc., can solve the problems of ineffective debridement, unreasonable configuration, hemostasis and impermeability, etc., to prevent adhesion and healing, and completely degrade safely. Absorbs and promotes healing

Inactive Publication Date: 2018-09-28
张河
View PDF1 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the configuration of the existing chitosan derivative colloid is unreasonable, and cannot effectively deb

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chitosan derivative colloidal solution

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0022] Example 1

[0023] The chitosan derivative colloidal liquid of the present invention includes 25 parts by weight of sodium carboxyaminoglucan, 15 parts of sodium carboxymethyl cellulose, 5 parts of nicotinamide, 4 parts of glycerin, 1 part of mannitol, and microcrystalline 2 parts of cellulose, 1 part of antioxidant, 5 parts of gelatin, 0.5 part of glutaraldehyde, 0.2 part of emulsifier and 60 parts of water for injection, the preparation method of chitosan derivative colloidal liquid includes the following steps:

[0024] S1. Add nicotinamide and sodium carboxymethyl cellulose to water for injection in turn, stir to dissolve, and add mannitol, heat and stir for 15-20 minutes to obtain solution A;

[0025] S2. Then add carboxyaminoglucan sodium to water for injection, heat and stir to dissolve, to obtain dissolving solution B;

[0026] S3. Mix dissolving liquid A and dissolving liquid B to obtain mixed dissolving liquid C;

[0027] S4. Add glycerin, microcrystalline cellulose an...

Example Embodiment

[0029] Example 2

[0030] The chitosan derivative colloidal liquid of the present invention includes 35 parts of carboxyaminoglucan sodium, 20 parts of carboxymethyl cellulose sodium, 10 parts of nicotinamide, 8 parts of glycerin, 5 parts of mannitol, and 5 parts of microcrystalline cellulose , 3 parts of antioxidant, 15 parts of gelatin, 1 part of glutaraldehyde, 0.6 part of emulsifier and 80 parts of water for injection. The preparation method of chitosan derivative colloidal liquid includes the following steps:

[0031] S1. Add nicotinamide and sodium carboxymethyl cellulose to water for injection in turn, stir to dissolve, and add mannitol, heat and stir for 15-20 minutes to obtain solution A;

[0032] S2. Then add carboxyaminoglucan sodium to water for injection, heat and stir to dissolve, to obtain dissolving solution B;

[0033] S3. Mix dissolving liquid A and dissolving liquid B to obtain mixed dissolving liquid C;

[0034] S4. Add glycerin, microcrystalline cellulose and antio...

Example Embodiment

[0036] Example 3

[0037] The colloidal liquid of chitosan derivative of the present invention includes 30 parts of sodium carboxyaminoglucan, 17 parts of sodium carboxymethyl cellulose, 8 parts of nicotinamide, 6 parts of glycerin, 3 parts of mannitol, and microcrystalline cellulose 3 parts, 2 parts of antioxidant, 10 parts of gelatin, 0.7 parts of glutaraldehyde, 0.4 parts of emulsifier and 70 parts of water for injection, the preparation method of chitosan derivative colloidal liquid includes the following steps:

[0038] S1. Sequentially add nicotinamide and sodium carboxymethyl cellulose to water for injection, stir to dissolve, and add mannitol, heat and stir for 15-20 minutes to obtain dissolving solution A;

[0039] S2. Then add carboxyaminoglucan sodium to water for injection, heat and stir to dissolve, to obtain dissolving solution B;

[0040] S3. Mix dissolving liquid A and dissolving liquid B to obtain mixed dissolving liquid C;

[0041] S4. Add glycerin, microcrystalline c...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a chitosan derivative colloidal solution. The solution is composed of 25-35 parts of sodium carboxyamino glucosamine, 15-20 parts of sodium carboxymethylcellulose, 5-10 parts of nicotinamide, 4-8 parts of glycerol, 1-5 parts of mannitol, 2-5 parts of microcrystalline cellulose, 1-3 parts of antioxidant, 5-15 parts of gelatin, 0.5-1 part of glutaraldehyde, 0.2-0.6 part of emulsifier and 60-80 parts of injection water. A preparation method of the solution includes the following steps of S1, adding nicotinamide and sodium carboxymethylcellulose into the injection water, stirring the mixture until the mixture is completely dissolved, adding mannitol, and then obtaining a dissolved solution A; S2, adding sodium carboxyamino glucosamine into the injection water, and conducting heating and stirring for dissolution to obtain a dissolved solution B; S3, mixing the dissolved solution A with the dissolved solution B to obtain a mixed dissolved solution C; S4, adding glycerol, microcrystalline cellulose and the antioxidant into the mixed dissolved solution C, stirring the solution uniformly, and then obtaining the chitosan derivative colloidal solution. The chitosan derivative colloidal solution has the advantages that wounds are effectively cleaned, resistance to bacteria and inflammation is achieved, bleeding is stopped, permeation is prevented, and healing is facilitated.

Description

technical field [0001] The invention relates to the technical field of medical products, in particular to a chitosan derivative colloid used for repairing human skin and wound epithelial tissue. Background technique [0002] At present, the configuration of the existing chitosan derivative colloid is unreasonable, and cannot effectively debride the wound, inhibit bacteria and anti-inflammation, stop bleeding and prevent leakage, prevent adhesion and promote healing. Therefore, urgently need those skilled in the art to research a kind of new chitosan derivative colloid. Contents of the invention [0003] The purpose of the present invention is to provide a chitosan derivative colloid in order to solve the above-mentioned deficiencies in the prior art. [0004] A chitosan derivative colloid of the present invention comprises 25-35 parts of carboxyaminodextran sodium, 15-20 parts of carboxymethylcellulose sodium, 5-10 parts of nicotinamide, 4-4 parts of glycerin in parts by ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61L24/10A61L24/08A61L24/00
CPCA61L24/104A61L24/001A61L24/0015A61L24/0042A61L24/08A61L2300/202A61L2300/404A61L2400/04C08L1/286C08L1/04C08L5/08
Inventor 张河
Owner 张河
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap