Intravascular photoacoustic-optical coherence tomography-near-infrared multi-mode imaging device and method

An optical coherence tomography, multimodal imaging technology, applied in the use of spectral diagnosis, catheter, diagnosis, etc., can solve the problems of poor photoacoustic image resolution, unable to provide chemical information, unable to apply blood vessels, etc., to achieve simple structure, Simplified inspection procedures, effect of high photoacoustic image resolution

Inactive Publication Date: 2018-10-09
SOUTH CHINA NORMAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0008] (1) The existing technology uses a vibrating mirror to realize two-dimensional scanning, which cannot be applied to blood vessels;
[0009] (2) The prior art adopts conical mirrors, and its disadvantage is that the required laser energy of this technology is large, and because the pulsed laser light does not converge, the resolution of the photoacoustic image is not good;
[0010] (3) The existing technology does not combine near-infrared light imaging and cannot provide chemical information of tissues. At the same time, the use of grin lenses cannot achieve better focus on single-mode light and multi-mode light at the same time

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Embodiment

[0041] Such as figure 1 As shown, the present embodiment is an intravascular photoacoustic-OCT-near-infrared light multi-modal imaging device, including a computer 1, a photoacoustic imaging system, an optical coherence tomography system, a near-infrared light imaging system, and a micro In the endoscopic probe 22, the intravascular OCT excitation light and photoacoustic excitation light use different light sources, and transmit and collect laser light through double-clad optical fiber 24; the intravascular OCT excitation light and near-infrared excitation light use the same light source, and pass The double-clad optical fiber is used for laser transmission and collection; the OCT signal and the near-infrared light signal used use the same detection method, that is, the linear array CCD10 is used to collect the OCT interference spectrum, and the image is processed by the computer, and the linear array CCD is used to collect the near-infrared light. Reflectance spectra, and ima...

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Abstract

The invention discloses an intravascular photoacoustic-optical coherence tomography-near-infrared multi-mode imaging device and method. The device comprises a computer, a photoacoustic imaging system,an optical coherence tomography system, a near-infrared optical imaging system, an optical fiber combiner, a double-cladding optical fiber photoelectric combination slip ring, a three-dimensional motion control system and a miniature endoscopic probe. On the one hand, the photoacoustic imaging system, the optical coherence tomography system and the near-infrared optical imaging system are connected to the computer; on the other hand, double-cladding optical fibers are disposed on the double-cladding optical fiber photoelectric combination slip ring through the optical fiber combiner and thenconnected to the miniature endoscope probe, and the double-cladding optical fiber photoelectric combination slip ring is disposed on a three-dimensional motion detection system. Integration of three intravascular imaging methods of photoacoustic imaging, OCT imaging and near-infrared optical imaging is achieved, detection procedures are simplified, the detection difficulty is reduced, and the situation that work is conducted by means of the three imaging methods simultaneously can be achieved.

Description

technical field [0001] The invention relates to the research field of vascular endoscopy, in particular to a photoacoustic-OCT-near-infrared light vascular endoscopy imaging device and method. Background technique [0002] In the 21st century, cardiovascular and cerebrovascular diseases have become the number one killer affecting human health, causing heavy casualties and consuming a huge amount of social wealth. It is well known that the rupture of atherosclerotic plaque is the main cause of acute cardiovascular and cerebrovascular events, so the study of plaque vulnerability is one of the most popular topics in the world. However, the detection and risk assessment of vulnerable plaques is still a major international problem. Although intravascular ultrasound imaging and intravascular optical imaging have been used in clinical practice, and provide guidance for the diagnosis and treatment of atherosclerosis. However, none of the existing technologies can comprehensively a...

Claims

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Application Information

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IPC IPC(8): A61B5/00A61B5/02
CPCA61B5/0035A61B5/0066A61B5/0075A61B5/0084A61B5/0095A61B5/02007
Inventor 陈重江詹坤河杨思华邢达
Owner SOUTH CHINA NORMAL UNIVERSITY
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