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Artificial tooth disinfectant and preparation method thereof

A technology for disinfectant and dentures, which is applied in the field of denture disinfectant and its preparation, can solve problems such as affecting the appearance and discoloration of dentures, and achieve the effects of easy degradation, environmental harmlessness, and enhanced antibacterial effect

Active Publication Date: 2018-10-09
上海典硕生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the disinfectant has a good bactericidal effect, long-term use of the disinfectant will cause discoloration of dentures and affect the appearance

Method used

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  • Artificial tooth disinfectant and preparation method thereof
  • Artificial tooth disinfectant and preparation method thereof
  • Artificial tooth disinfectant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A denture disinfectant solution comprises the following components in parts by weight: 11 g of chlorhexidine, 8 g of 1,3-propanediol, 0.8 g of peppermint, 6 g of Periplaneta americana extract, and 80 g of distilled water.

[0023] The extraction method of the American cockroach extract is as follows: take the American cockroach, crush it, pass through a 50-mesh sieve, use 12 times the amount of 75% ethanol for percolation extraction for 2 hours, add 6 times the amount of 75% ethanol to the dregs and continue the percolation extraction for 1 hour , discard the medicinal residues, combine the two extracts, recover ethanol under reduced pressure below 50°C, and concentrate to an extract with a ratio of medicinal liquid of 1:1.1 to prepare.

[0024] The preparation method of above-mentioned denture disinfectant is carried out according to the following steps:

[0025] (1) According to the parts by weight, take 11g of chlorhexidine, add 80g of distilled water, heat up to 65°...

Embodiment 2

[0029] A denture disinfectant solution comprises the following components in parts by weight: 9 g of chlorhexidine, 4 g of 1,3-propanediol, 0.5 g of peppermint, 3 g of Scutellaria baicalensis extract, and 60 g of distilled water.

[0030] The extraction method of the Scutellaria baicalensis extract is as follows: take Scutellaria scutellariae, crush it, pass through a 50-mesh sieve, add 6 times the amount of 60% ethanol to soak, reflux extraction, and filter; recycle the ethanol from the filtrate until it has no alcohol smell; heat the water to 80°C , adjust the pH value to 1.0, keep warm for 30min, stand still, precipitate, and centrifuge; take the precipitate and add 10 times of water and stir to form a suspension, add 20% NaOH to adjust the pH value to neutral, stand still, and centrifuge; take the supernatant and heat to 40°C, add an equal volume of ethanol under stirring, mix well, let stand, and centrifuge; take the supernatant, adjust the pH value to 1.0 with hydrochlori...

Embodiment 3

[0036] A denture disinfectant solution comprises the following components in parts by weight: 12 g of chlorhexidine, 10 g of 1,3-propanediol, 1 g of peppermint, 8 g of leech extract, and 120 g of distilled water.

[0037] The extraction method of the leech extract is as follows: take dry leeches and grind them into powder, pass through a 50-mesh sieve, add 8 times the water in parts by weight, soak for 24 hours, centrifuge under the condition of a rotating speed of 8000rpm, take the supernatant, Made by evaporating to dryness under reduced pressure at low temperature.

[0038] The preparation method of above-mentioned denture disinfectant is carried out according to the following steps:

[0039] (1) According to the parts by weight, take 12g of chlorhexidine, add 120g of distilled water, heat up to 70°C, and stir for 30min;

[0040] (2) Cool down to 45°C, add 10g of 1,3-propanediol, 1g of mint, and stir for 8 minutes;

[0041] (3) Cool down to room temperature, add 8 g of le...

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Abstract

The invention discloses an artificial tooth disinfectant and a preparation method thereof. The artificial tooth disinfectant is prepared from the following components in parts by weight: 9 to 12 partsof chlorhexidine, 4 to 10 parts of 1,3-propylene glycol, 0.5 to 1 part of herba menthae, 3 to 8 parts of antibacterial extract and 60 to 120 parts of distilled water. According to the artificial tooth disinfectant prepared by the invention, the antibacterial extract, the herba menthae and the 1,3-propylene glycol are added on the basis of a traditional chlorhexidine disinfectant, and the antibacterial effect is enhanced; the problem that an artificial tooth is washed by independently utilizing the chlorhexidine disinfectant so that the color of an artificial tooth denture base is changed is overcome; the antibacterial extract provided by the invention is extracted from natural plants or animals and the extract is harmless to the environment and is easy to degrade.

Description

technical field [0001] The invention belongs to the technical field of stomatology material preparation, and in particular relates to a denture disinfectant and a preparation method thereof. Background technique [0002] Dentures are artificial teeth that replace missing natural teeth. Severe periodontal disease, dental caries and trauma can cause partial or even complete loss of dentition. Tooth loss can affect the face, pronunciation, and chewing functions, and increase the burden on the stomach. If it is not repaired in time, the adjacent teeth will tilt and shift, and the opposing teeth will elongate, causing occlusal disorder. Part of the missing dentition can be repaired with fixed or removable dentures, or with complete dentures if there are no teeth. [0003] Dentures need to be disinfected and cleaned frequently. Incomplete cleaning and disinfection of dentures will produce peculiar smell, affect diet, reduce gastrointestinal function; breed bacteria, cause ulcers...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/9789A61K8/43A61K8/34A61Q11/02
CPCA61K8/345A61K8/43A61K8/987A61Q11/02A61K8/9789
Inventor 周美英
Owner 上海典硕生物科技有限公司
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