The utility model relates to the technical field of false teeth, and discloses a removable false tooth anti-loosening base which comprises a base body, a tooth groove is formed in the base body, a false tooth is installed in the tooth groove, a connecting plate is connected to the side face of the base body, and a positioning plate extending into the base body is fixedly connected to the lower portion of the side face of the connecting plate. A supporting seat for mounting a false tooth is fixedly connected to the top of the positioning plate, through holes corresponding in position are formed in the supporting seat and the positioning plate, bolts for fixing the false tooth are mounted in the through holes, a mounting groove for mounting the bolts is formed in the bottom surface of the base, and clamping rings are fixedly connected to the side surface of the connecting plate and located on the two sides of the base. The connecting plate is matched with the clamping ring, so that the base plate can be fixedly arranged at a tooth-missing part without the help of an external positioning tool, and convenience and rapidness are realized; when the denture is damaged, only the independent denture needs to be replaced, the whole base and the denture do not need to be replaced, and resource waste is reduced.