Moxifloxacin pharmaceutical preparation

A pharmaceutical preparation, the technology of moxifloxacin, applied in the field of moxifloxacin pharmaceutical preparations, can solve the problems of discoloration of moxifloxacin and inability to overcome the discoloration of moxifloxacin hydrochloride

Active Publication Date: 2018-10-16
BEIJING WINSUNNY PHARMA CO LTD
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the inventors found that the preparation still cannot overcome the discoloration problem of moxifloxacin hydrochloride
[0008] Therefore, further studies on moxifloxacin formulations are needed to solve the problem of discoloration of moxifloxacin

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Moxifloxacin pharmaceutical preparation
  • Moxifloxacin pharmaceutical preparation
  • Moxifloxacin pharmaceutical preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023]

[0024] Preparation:

[0025] a. Mix moxifloxacin hydrochloride, gallic acid, sodium oleate, microcrystalline cellulose, lactose, and croscarmellose sodium evenly to prepare a mixture;

[0026] b. adding 30% ethanol aqueous solution to step a, granulating to obtain drug granules;

[0027] c. Compressing the drug granules into tablets.

Embodiment 2

[0029]

[0030] The preparation method is the same as in Example 1.

Embodiment 3

[0032]

[0033] The preparation method is the same as in Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a moxifloxacin pharmaceutical preparation which specifically comprises moxifloxacin or a salt thereof, a diluent, a disintegrating agent, gallic acid and sodium oleate. According to the moxifloxacin pharmaceutical preparation, by using the gallic acid and the sodium oleate, the color changing problem in the preparation and storage processes of the moxifloxacin preparationcan be solved quite well; and meanwhile, the problem of poor fluidity of the moxifloxacin can further be effectively relieved, preparation smoothness of the moxifloxacin pharmaceutical preparation isensured, and the moxifloxacin pharmaceutical preparation is suitable for industrial mass production.

Description

technical field [0001] The invention relates to a pharmaceutical preparation of an antibacterial drug, in particular to a pharmaceutical preparation of moxifloxacin, and a preparation method of the preparation. Background technique [0002] Moxifloxacin hydrochloride is a broad-spectrum and active 8-methoxyfluoroquinolone antibacterial drug. It has broad-spectrum antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, anaerobic bacteria, acid-fast bacteria, and atypical microorganisms such as Mycoplasma, Chlamydia and Legionella. The antibacterial mechanism is to interfere with II and IV topoisomerases, which are key enzymes in controlling DNA topology, DNA replication, repair and transcription. Moxifloxacin is the fourth generation of fluoroquinolone antibiotics. Because of its broad antibacterial spectrum, low drug resistance, strong antibacterial effect, long half-life, and low phototoxicity, it has become a very effective anti-infective agent. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4709A61K47/12A61K47/38A61K47/32A61P31/04
CPCA61K31/4709A61K47/12
Inventor 黄玉锋王帅杨西邈耿玉先产运霞
Owner BEIJING WINSUNNY PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap