The invention discloses a manufacturing method of a resin high polymer material and silica gel simulation animal and plant model, which comprises the following steps: (1) preparing manufacturing materials and instruments, the materials including various animals and plants and insects, epoxy resin AB glue and a drying agent (aluminum oxide); the insect collection materials comprise a collection net, a poison bottle, a plastic bag, long tweezers, gloves and a triangular paper bag; the insect dried specimen model is manufactured through tweezers, pins, insect needles, wing spreading plates, a three-stage table, parchment paper, label paper and a specimen box. According to the manufacturing method of the resin high polymer material and the silica gel simulation animal and plant model, a delicate resin specimen model is finally obtained, meanwhile, the steps in the method are more specific and perfect, the success rate of specimens is high, and the specimens manufactured according to the method are easy and convenient to operate, excellent in transparency, tough in texture, not prone to being damaged, non-toxic, free of environment pollution and suitable for popularization and application. And no toxic substance or pollutant is used in the method, so that the method is more environment-friendly.