Manual tracheotomy tube with antibacterial nano material coating

A nano-antibacterial material and a technology of tracheotomy cannula, which are applied in the direction of tracheal intubation, coating, catheter, etc., can solve the problems of poor antibacterial property, easy infection, high irritation, etc., and achieve good performance, low cost, The effect of high local concentration

Inactive Publication Date: 2010-02-24
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the tracheostomy tubes used clinically are highly ir

Method used

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  • Manual tracheotomy tube with antibacterial nano material coating

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] An artificial tracheotomy sleeve is composed of a flexible tube body 2 , an inflation / deflation tube 5 , an inflatable cuff 6 and a liquid discharge tube 9 . The two ends of the flexible tube body 2 are the connecting head 3 and the insertion end 7 respectively, the connecting head 3 is connected with the ventilator; the insertion end 7 is connected with the patient's trachea. An inflatable cuff 6 is provided at the lower part of the flexible tube body 2 (near the insertion end 7). Filling / deflation pipe 5 is longitudinally embedded in the tube wall on one side of the flexible pipe body 2, and the filling / deflation pipe 5 is drawn near the junction of the short wing 1 and the tracheotomy sleeve, and the gas nozzle 4 is installed at the gate, which can be connected with the inflation device. The side opening of the intubation tube wall of the inflatable cuff 6 is connected to the mouth of the inflation / deflation tube 5 embedded in the wall of the tracheotomy sleeve, and ...

Embodiment 2

[0027] Mix 6g of polyvinylpyrrolidone, 0.03g of ticarcillin / clavulanic acid compound preparation, 0.3g of silver-loaded zeolite antibacterial agent, 100ml of ethanol, 30ml of dimethylformamide, and 30ml of ethyl acetate, mix well, and make a mixed solution for later use ;

[0028] Immerse the artificial tracheotomy sleeve prepared above according to the method of Example 1 in the mixed solution for 1 minute, take it out, and dry it at 60-70°C for about 5-10 minutes to obtain a nano-antibacterial material coating of the present invention The average thickness of the coating 10 of the artificial tracheotomy sleeve is 0.5mm.

Embodiment 3

[0030] 10g of polyvinylpyrrolidone, 0.1g of cefoperazone / sulbactam composite preparation, 0.2g of silver-loaded zirconium phosphate antibacterial agent, 100ml of ethanol, 40ml of dimethylformamide, 30ml of ethyl acetate, and 10ml of acetone were mixed evenly to prepare The solution is ready for use;

[0031] Immerse the tracheotomy sleeve prepared above according to the method of Example 1 in the mixed solution for 2 minutes, take it out, and dry it at 60-70°C for about 5-10 minutes to obtain another nano-antibacterial material coating of the present invention The average thickness of the coating 10 of the artificial tracheostomy tube is 1mm.

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Abstract

The invention relates to the technical field of medical apparatus. The generation of ventilator-associated pneumonia is the result of the inspiration of secretion with pathogen, wherein the bacterialcontamination in a ventilator air tube is also a principal element for causing the ventilator-associated pneumonia. The invention aims to provide a manual tracheotomy tube with broad spectrum of antimicrobial activity and controllable slow-release medicaments, comprising a flexible tube body and a tampon system attached to the outside of the tube body, wherein the inner surface and the outer surface of the tracheotomy tube are combined with macromolecular polymer antimicrobial coatings in which medicaments with pharmacologic effect are loaded. The invention not only achieves the efficacy of providing air paths for a traditional tracheotomy tube and keeping the respiratory tract smooth, but also has excellent bacteriostatic effect and the slow release effect of the controllable medicaments,thereby providing a wide application prospect for clinical application of the manual tracheotomy tube.

Description

technical field [0001] The invention relates to the technical field of medical devices, and relates to an artificial tracheotomy sleeve coated with a nanometer antibacterial material. Background technique [0002] With the development of science and technology and the improvement of people's health awareness, the application of biomaterials in clinical medicine is becoming more and more extensive. While biomaterials bring convenience to clinical treatment, there are still some problems. It has been found that biomaterials, whether long-term or short-term indwelling in the human body, often cause various bacterial infections. At present, infectious diseases still account for 1 / 3 of the causes of death in the world's population, and pneumonia ranks first, among which severe pneumonia seriously threatens human health. Hospital acquired pneumonia (HAP) is the most common nosocomial infection. HAP is the No. 1 nosocomial infection in my country, with a prevalence rate of 1.3% t...

Claims

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Application Information

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IPC IPC(8): A61M16/04A61L29/08A61L29/16
Inventor 李文放林兆奋刘雪峰张强王虑陈德昌
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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