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Multi-channel quick detection micro-fluid detecting chip

A technology for detecting chips and microfluids, which is applied in laboratory appliances, laboratory containers, chemical instruments and methods, etc., can solve the problems of unreasonable inlet design, small detection flux, complex structure, etc., and achieve flow Fast, easy sample injection, and simple chip structure

Pending Publication Date: 2018-11-06
NANJING LANSION BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned technical scheme has low detection throughput, complex structure and high cost, and unreasonable design of the injection port may easily cause sample contamination

Method used

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  • Multi-channel quick detection micro-fluid detecting chip
  • Multi-channel quick detection micro-fluid detecting chip
  • Multi-channel quick detection micro-fluid detecting chip

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: The multi-channel rapid detection microfluidic detection chip includes a chip body, and the chip body is provided with a chip sampling port 7, a plurality of mutually independent detection chambers 8 and microfluidic channels 5, and the chip sampling port 7 The micro-channel 5 communicates with the detection chamber 8, the chip body also includes an electrode 4, and the detection chamber 8 is connected to the electrode 4; the micro-channel 5 includes a main flow channel 501 and 5 branch channels. The microfluidic channel 502, the end of the main flow channel 501 is divided into five microfluidic channels 502, and the five microfluidic channels 502 communicate with the five independent detection chambers 8 one by one; the main flow The other end of the channel 501 communicates with the chip sampling port 7; the chip body sequentially includes a bottom layer 1, an intermediate layer 2 and an upper cover layer 3 from bottom to top, and the bottom layer 1, the ...

Embodiment 2

[0034] Embodiment 2: The difference from Embodiment 1 is that the structure of the chip sampling port 7 is different, and the bottom layer 1, the middle layer 2 and the upper cover layer 3 cooperate to define a closed microflow channel 5, a detection chamber 8 and a funnel Area 9; one side of the lower end of the bottom layer 1 is provided with a gap 10, and the liquid injection port 701, the funnel area 9 and the gap 10 are respectively arranged on the upper cover layer 3, the middle layer 2 and the corresponding bottom layer 1 The position and size are different; the chip sampling port 7 is composed of a liquid injection port 701, a funnel area 9 and a gap 10 and is connected to the bottom of the detection chamber 8 through the micro flow channel 5; specifically: the multiple The channel rapid detection microfluidic detection chip includes a chip body, and the chip body is provided with a chip sampling port 7, a plurality of mutually independent detection chambers 8 and a mic...

Embodiment 3

[0035]Embodiment 3: The difference from Embodiment 1 is that the structure of the chip sampling port is different, and the bottom plate layer 1, the middle layer 2 and the upper cover layer 3 cooperate to define a closed micro flow channel 5, a detection chamber 8 and a funnel area 9. A notch 10 is provided on one side of the lower end of the bottom layer 1, and the liquid injection port 701, the funnel area 9 and the notch 10 are respectively arranged at corresponding positions on the upper cover layer 3, the middle layer 2 and the bottom layer 1 and different sizes; the chip sampling port 7 is composed of a liquid injection port 701, a funnel region 9 and a gap 10 and is connected to the bottom of the detection chamber 8 through the micro-channel 5; specifically: the multi-channel The rapid detection microfluidic detection chip includes a chip body, and the chip body is provided with a chip sampling port 7, a plurality of mutually independent detection chambers 8 and micro fl...

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Abstract

The invention discloses a multi-channel quick detection micro-fluid detecting chip. The multi-channel quick detection micro-fluid detecting chip comprises a chip body, wherein a chip sampling hole, aplurality of detecting rooms which are independent from one another and micro runners are arranged on the chip body; the chip sampling hole is communicated with the detecting rooms through the micro runners; the chip body further comprises an electrode; the detecting rooms are connected with the electrode; each micro runner comprises a main-flow channel and a plurality of branch micro-fluid channels, the tail end of the main-flow channel is divided into the branch micro-fluid channels, and the branch micro-fluid channels are in one-to-one correspondence and communication with the detecting rooms which are independent from one another; and the other end of the main-flow channel is communicated with the chip sampling hole. According to the multi-channel quick detection micro-fluid detectingchip disclosed by the invention, the main-flow channel and the branch micro-fluid channels are arranged for guiding flow of a blood sample, so that samples can be injected into the reaction chambers at the same time from one sample chamber, and the samples are not contained, and therefore, sample injection is easy, the samples can be detected at the same time, and the multi-channel effect is achieved; and the chip is simple in structure, is convenient to operate, improves detecting efficiency, reduces consumption of resources, and reduces cost.

Description

technical field [0001] The invention belongs to the technical field of medical equipment, in particular to a multi-channel rapid detection microfluid detection chip. Background technique [0002] Microfluidics is a technology applied across various disciplines including engineering, physics, chemistry, microtechnology and biotechnology. Microfluidics involves the study of small volumes of fluids and how such small quantities of fluids are manipulated, controlled and used in various microfluidic systems and devices, such as microfluidic chips. For example: microfluidic biochips (referred to as "lab-on-a-chip") are used in the field of molecular biology to integrate assay operations for purposes such as analyzing enzymes and DNA, detecting biochemical toxins and pathogens, diagnosing diseases, and the like. [0003] Microfluidic chip (microfluidic chip) is currently a hot field in the development of Miniaturized Total Analysis Systems. The microfluidic chip analysis uses the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/5027B01L2300/0887B01L2300/0864B01L2300/0645B01L2200/10B01L3/502715B01L3/502723B01L2300/0816B01L2300/161
Inventor 许行尚杰弗瑞·陈
Owner NANJING LANSION BIOTECH CO LTD
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