Antibacterial mouthwash containing licorice flavonoids and preparation method thereof

A technology of licorice flavonoids and mouthwash, which is applied in the field of medicine and daily chemical products, can solve the problems of complex preparation process of extracts, various combinations of plant raw materials, and difficult production, so as to reduce oral bacteria, relieve gum swelling and pain, and be easy to produce. Effect

Active Publication Date: 2021-07-30
亿利耐雀生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In the above patents, there are problems such as the combination of various plant raw materials and the complex preparation process of the extract, which are not easy to apply to production.

Method used

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  • Antibacterial mouthwash containing licorice flavonoids and preparation method thereof
  • Antibacterial mouthwash containing licorice flavonoids and preparation method thereof
  • Antibacterial mouthwash containing licorice flavonoids and preparation method thereof

Examples

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Effect test

preparation example Construction

[0041] The preparation method of Scutellaria baicalensis extract is as follows:

[0042] Take 300 g of Scutellaria baicalensis, add ethanol aqueous solution (mass fraction: 80%) whose weight ratio is 10 times, reflux extraction at 85° C. for 2 hours, and then filter, and the medicinal material is repeatedly extracted twice. The combined filtrates were concentrated and dried to obtain the Scutellaria baicalensis extract.

[0043]The preparation method of magnolia bark extract is as follows:

[0044] Get 300g of Magnolia officinalis, add its weight ratio of 10 times the ethanol aqueous solution (mass fraction is 80%), reflux extraction at 85 ℃ for 2 hours, then filter, and the medicinal material is repeatedly extracted twice. The filtrates were combined, concentrated and dried to obtain the Magnolia officinalis extract.

Embodiment 1

[0045] Embodiment 1: A kind of antibacterial mouthwash containing licorice flavonoids

[0046] Formula ingredients (200g), in terms of mass percentage, consist of: licorice flavonoids, 0.2%; Scutellaria baicalensis extract, 0.5%; Magnolia officinalis extract, 0.2%; Thymol 0.1%; Poloxamer 407, 2%; Glycerin, 10%; Propylene Glycol, 10%; Menthol, 0.1%; Deionized water added to 200g.

[0047] Preparation method: Take poloxamer 407, glycerin, propylene glycol, scutellaria baicalensis extract, and magnolia bark extract according to the formula, heat to 80-85°C, stir for 10 minutes, add appropriate amount of deionized water, and reserve 10g of the rest Measure water. Keep warm at 80-85°C, stir for 1 hour, cool to room temperature, and filter until the filtrate is clear. Collect the filtrate, add licorice flavonoids, heat to 80-85°C, stir for 1 hour until completely dissolved, cool to 50°C, add thymol and menthol, and add the remaining water, stir for 1 hour until completely dissolve...

Embodiment 2

[0048] Embodiment 2: A kind of antibacterial mouthwash containing licorice flavonoids

[0049] Formula ingredients (200g), in terms of mass percentage, consist of: licorice flavonoids, 0.2%; Scutellaria baicalensis extract, 0.5%; Magnolia officinalis extract, 0.1%; Thymol 0.1%; Poloxamer 407, 1%; Glycerin, 10%; Propylene Glycol, 5%; Menthol, 0.1%; Deionized water added to 200g.

[0050] Preparation method: Take poloxamer 407, glycerin, propylene glycol, scutellaria baicalensis extract, and magnolia bark extract according to the formula, heat to 80-85°C, stir for 10 minutes, add appropriate amount of deionized water, and reserve 10g of the rest Measure water. Keep warm at 80-85°C, stir for 1 hour, cool to room temperature, and filter until the filtrate is clear. Collect the filtrate, add licorice flavonoids, heat to 80-85°C, stir for 1 hour until completely dissolved, cool to 50°C, add thymol and menthol, and add the remaining water, stir for 1 hour until completely dissolved...

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Abstract

The invention discloses an antibacterial mouthwash containing licorice flavonoids and a preparation method thereof. The antibacterial mouthwash consists of: 0.01-1% of licorice flavonoids, 0.05-3% of baicalin extract, and Magnolia officinalis extract Thymol 0.01-3%, thymol 0.01-1%, auxiliary agent 5-50%, and the balance is water. The invention also discloses its preparation method. The mouthwash prepared by the invention can keep the breath fresh, clean the tartar, reduce oral bacteria, care for the health of the oral cavity and gums, and avoid dental caries, bad breath and dental plaque. At the same time, it has antibacterial and anti-inflammatory effects, relieves gum swelling and pain, and promotes the healing of oral ulcers. The mouthwash system is stable, the preparation method is simple, and the application prospect is broad.

Description

technical field [0001] The invention belongs to the technical field of medicine and daily chemical products, and in particular relates to an antibacterial mouthwash for daily oral care containing active components of licorice flavonoids and a preparation method thereof. Background technique [0002] With the development of economy and society and the continuous improvement of living standards, people's awareness of oral health care has been greatly enhanced, and oral care products have gradually developed from a single toothpaste to toothpaste, toothpaste, mouthwash and other care products. The purpose of people's consumption has also changed from a single cleaning of teeth to tooth care and beauty, cleaning the mouth and preventing and treating oral diseases. Halitosis, dental caries, and oral ulcers are more common in oral diseases. [0003] Mouthwash is a new product in the era of science and technology. It combines a variety of medicinal ingredients for the treatment of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/49A61K8/34A61K36/575A61Q11/00A61P1/02A61P31/02A61P29/00A61K31/05A61K31/352
CPCA61K8/347A61K8/498A61K31/05A61K31/352A61K36/539A61K36/575A61K2236/333A61K2236/39A61K2236/51A61Q11/00A61K8/9789A61P1/02A61P29/00A61P31/02A61K2300/00
Inventor 魏元刚刘泽宇杨永安钟慧左婧
Owner 亿利耐雀生物科技有限公司
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