Medical disinfecting ultrasonic coupling agent

Abstract

The invention discloses a medical disinfecting ultrasonic coupling agent, which is prepared from the following components: 0.5 to 1.5% of carbomer, 30 to 50% of propylene glycol, 0.5 to 2.5% of trichlorohydroxydiphenyl ether, 2 to 10% of glycerol, 0.1 to 1.5% of triethanolamine, and the balance of deionized water. The medical disinfecting ultrasonic coupling agent is prepared by the following steps: respectively preparing the above components by mass percentage to be ready for use; heating deionized water to 60 DEG C; adding the trichlorohydroxydiphenyl ether to the deionized water and stirring and dissolving for more than 3 h until all are dissolved into a solution; adding the propylene glycol, glycerol and triethanolamine to the obtained transparent colloid, heating and stirring, and heating to the maximum temperature of not more than 40 DEG C; keeping the temperature of the mixture obtained in the previous step at a temperature of 25 DEG C for 20 min, and naturally cooling to normaltemperature, after the liquid is transparent, molding into a gel; filling, sealing and storing. The medical disinfecting ultrasonic coupling agent provided by the invention has the advantages of goodbiocompatibility, safety, non-toxicity, no cytotoxicity, no irritation and no allergy.

Description

technical field [0001] The invention relates to a couplant, in particular to a sterile medical ultrasonic couplant, and relates to the technical field of couplant disinfection. Background technique [0002] Medical coupling agent is a medical product composed of a new generation of water-based polymer gel, which has a neutral pH value and is harmless and non-toxic to the human body. The existing medical ultrasonic coupling agent is mainly composed of hydroxyethyl cellulose, hydroxypropyl cellulose, and carbomer as a viscosity regulator, and then combined with propylene glycol solvent and deionized water. It is to establish a coupling between the sound head (ultrasound probe or treatment head) and the human body during clinical ultrasonic diagnosis or ultrasonic treatment, so that the ultrasonic waves emitted by the sound head can enter the human body smoothly to obtain reliable detection and diagnosis images, or achieve effective treatment. The existing medical ultrasonic ...

AI Technical Summary

Problems solved by technology

However, polyhexamethylene biguanide, benzalkonium chloride, benzalkonium bromide, chlorhexidine acetate, etc. belong to cationic surfactants. Antimicrobials can damage transducers or affect the quality of ultrasound images

At the same time, chemically speaking, there are a large number of carboxyl groups in the carbomer molecule, which is an anionic polymer and cannot be sterilized with cationic bacteria such as polyhexamethylene biguanide, benzalkonium chloride, benzalkonium bromide, and chlorhexidine acetate. Agent compatibility

Methyl and propyl parabens antimicrobial preservatives are effective against molds and yeasts, but often cause allergic reactions on the skin and mucous membranes

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