Liver cancer resistant health care product containing costunolide
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A woody hydrocarbon lactone, anti-liver cancer technology, applied in medical preparations containing active ingredients, food ingredients containing natural extracts, anti-tumor drugs, etc. It is easy to produce drug resistance and other problems, to achieve the effect of improving rehabilitation status and quality of life, avoiding cytotoxicity, and easy to obtain
Inactive Publication Date: 2018-12-18
LIAONING UNIVERSITY
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Moreover, the reactivity of anti-liver cancer drugs is low, drug resistance is easy to develop, and the drug toxicity is high. The prognosis of liver cancer patients is still not optimistic. It is of urgent significance to develop more effective drugs for the treatment of liver cancer
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Embodiment 1
[0020] Embodiment 1 contains the anti-liver cancer health care product of woody lactone
[0021] (1) Preparation of woody hydrocarbon lactone
[0022] The process combination of pulverization-ethanol leaching-microwave-assisted extraction step-by-step method to extract woody lactone is as follows:
[0023] 1) Muxiang pulverization: take an appropriate amount of dried rhizomes of Muxiang, pulverize them with a pulverizer, and pass through a 200-mesh sieve to obtain Muxiang powder;
[0024] 2) Ethanol extraction: according to the ratio of material to liquid 1: (5-15), take the powder of cayenne and 60-80% ethanol, extract at room temperature for 2-3 hours, and obtain the ethanol extraction mixture;
[0025] 3) Microwave-assisted extraction: microwave the ethanol extraction mixture at a temperature of 40-50°C for an extraction time of 80-90 minutes, centrifuge, and take the supernatant;
[0026] 4) Concentrating the supernatant by rotary evaporation, filtering with filter paper...
Embodiment 2
[0051] Embodiment 2 contains the anti-liver cancer health care product of woody hydrocarbon lactone
[0052] (one)-(five) with embodiment 1.
[0053] (6) Anti-hepatocarcinoma health care products containing couscous lactone, which are composed of the following raw materials by weight percentage:
[0055] Embodiment 3 contains the anti-liver cancer health product of woody lactone
[0056] (one)-(five) with embodiment 1.
[0057] (6) Anti-hepatocarcinoma health care products containing couscous lactone, which are composed of the following raw materials by weight percentage:
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Abstract
The invention discloses a liver cancer resistant health care product containing costunolide. The health care product comprises following components in percentage by weight: 50 to 70% of costunolide, 7.5 to 12.5% of walnut bark extract, 7.5 to 12.5% of toad extract, 7.5 to 12.5% of croton seed extract, and 7.5 to 12.5% of radix zanthoxyli extract. Innovatively, costunolide is taken as the main rawmaterial of the liver cancer resistant health care product; other traditional Chinese medicines are taken as auxiliary materials to enhance the curative effect; and the main raw material and auxiliarymaterials are blended to form the health care product capable of preventing liver cancer. Provided costunolide composition can obviously inhibit the reproduction of human liver cancer cells, has a good curative effect, solves the problems that in chemical therapy and chemically synthesized drugs, the cytotoxicity and side effect are severe, the cost is high, and the relapse rate is high, and improves the health and life quality of patients, moreover, the raw materials are easily available, and references are provided for further research and clinical application.
Description
technical field [0001] The invention belongs to the field of health products, and in particular relates to an anti-liver cancer health product containing couscous lactone. Background technique [0002] Liver cancer is one of the most common malignant tumors in my country. Its fatality rate ranks third among all kinds of tumors in the world, second only to gastric cancer and lung cancer. Its high degree of malignancy and poor prognosis seriously threaten the life and health of patients. . At present, the clinical treatment of liver cancer is mainly based on surgery. Since most patients have clinical metastasis when they are diagnosed, the treatment effect is poor, and liver cancer is prone to recurrence after surgery. The uncontrolled proliferation and metastasis of liver cancer cells are the main causes of death in patients with liver cancer. Therefore, the key to anti-liver cancer therapy is how to control the proliferation, metastasis and invasion of liver cancer cells. M...
Claims
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