115results about How to "High recurrence rate" patented technology

An apparatus and methods for performing ablation of myocardial tissues are disclosed. The apparatus includes a plurality of ablation electrode configurations to which nanosecond pulsed electric fields are applied. The methods relate to therapies to treat cardiac arrhythmias, such as, atrial fibrillation and scar-related ventricular tachycardia, amongst others. The affected myocardial tissues are ablated creating a plurality of lesions enabled by the nanosecond pulsed electric fields applied to either penetrating electrodes, endo-endo electrodes, or endo-epi electrodes. Different electrophysiological tests are performed to assess the application of nanosecond pulsed electric field ablation to specific desired tissue location within the heart. Test results show the potential to overcome limitations of current ablation therapies, thereby providing patients and doctors a superior treatment for cardiac arrhythmias.

A high peak power optical rest and combination of plural of the resonators, particularly to excite a light generator in the extreme ultraviolet. An optical resonator with a solid state amplifying medium is pulsed and pumped by diodes operating continuously. The optical resonator includes at least two laser rods, at least one mechanism to trigger optical pulses, the triggering mechanism located in a part of a cavity in which the laser beam diverges least, and first and second mirrors that delimit the cavity, the first mirror being highly reflecting and the second mirror being partly reflecting.

The invention mainly relates to a wart treating medicament and a preparation method thereof. The wart treating medicament comprises the following major raw materials by weight: 6-70 grams of java brucea fruit, 5-70 grams of isatis root, 6-60 grams of glabrous greenbrier rhizome, 6-60 grams of lightyellow sophora root, 6-60 grams of weeping forsythia, 6-60 grams of unprocessed coix seed, 6-60 grams of honeysuckle flower and 6-60 grams of red-rooted salvia root. The preparation method of the wart treating medicament comprises the following steps of: A, preparing a film coating agent 1#; and B, preparing a film coating agent 2#. By applying a No.1 medicinal film once, all warts can be removed, and viruses in a wart at an infection focus are cleared completely at first. By coating a No.2 medicinal film on and around the infection focus (once every day), residual viruses can be cleared completed, and the aim of healing is fulfilled.

The invention discloses trichoderma solid granules for preventing and controlling tobacco soil-borne fungus diseases and a preparation method thereof, and aims to provide an effective, nontoxic, safe and residue-free bio-control microbial inoculum which is simple and convenient to use. The strain for producing the microbial inoculum is trichoderma harzianum TR13 with a preserving number of CGMCC No.2849. The preparation method comprises: (1) rejuvenescence of the strain; (2) preparation of the strain; (3) fermentation culture of a liquid; (4) fermentation culture of a solid; and (5) preparation.

The invention discloses a diagnosis and treatment preparation with a multi-stimuli-responsive medicine controlled release function and a preparation method and application thereof. According to the prepared preparation, polypyrrole nano particles are used as a core and externally modified by a cyclodextrin-chemotherapeutics compound and a targeted group, and the preparation has the effects of multi-stimuli-responsive medicine controlled release, photoacoustic imaging and chemotherapeutic and photo-thermal combined treatment. According to the preparation, three medicine controlled release mechanisms including pH values, gelatinase and photo-thermal response are combined, and the selectivity of chemotherapeutics to tumors is improved; imaging and treatment are fused, in-vivo distribution ofthe preparation can be monitored in real time, and the laser radiation position, power and time during photo-thermal treatment are guided; and chemotherapeutics and photo-thermal treatment are combined, so that the tumor recurrence rate is effectively lowered. By means of the composite preparation, the diagnosis and treatment efficiency is effectively improved, the medical effect is improved, thetoxic and side effects are lowered, and the diagnosis and treatment preparation has good clinic application prospects.

The invention belongs to the biochemical analysis field and relates to a method which makes use of the block polymer coating with a micro-phase separation structure to carry out on-target elution-free in-situ desalting and synchronous enrichment on the peptide and protein samples to avoid samples loss and can directly carry out matrix-assisted laser analysis ionization mass spectrometry analysis and identification on the enriched samples. The invention can realize desalting dispensing with extra eluted desalting step and excessive matrix solution and can directly make MALDI MS analysis; the invention successfully achieves the characteristics of sample on-target in-situ elution-free desalting and enrichment at the first time and has the advantages of high sensitivity, high reproducibility, high flux and strong salt-tolerant ability, which is economical and time-saving; the invention can be widely used in the field of proteomics and also greatly expands the application scope of the polymer coating technology.

The invention discloses a preparation method of a zero-VOC high-performance alcoholic acid emulsion. The preparation method comprises the following steps: firstly, performing alcoholysis on a drying oil or a semi-drying oil and a polyhydric alcohol under the action of a high temperature and an alcoholysis catalyst, and then performing an esterification reaction with polybasic acid to obtain an air-drying alkyd resin; next, moving the alkyd resin to a reaction kettle with a circulating water jacket, heating the circulating water in the jacket of the reaction kettle until an emulsification temperature, controlling the rotating speed to the range of 170rpm to 180rpm, adding a neutralizer to the reaction kettle and mixing thoroughly and evenly; keeping the temperature unchanged, and adding a proper amount of emulsifier to the reaction kettle, adjusting the rotating speed to the range of 250rpm to 270rpm, and stirring for 30 to 45 minutes; heating deionized water equivalent to the resin by mass until an emulsification temperature and slowly and dropwise adding the deionized water to the reaction kettle at a constant speed in about 3-5 hours; and furthermore, cooling in water bath under stirring until a room temperature, regulating the pH value of the emulsion by use of a pH regulator to the range of 5-7, and filtering to obtain the zero-VOC high-performance alcoholic acid emulsion. According to the preparation method, zero VOC emission is really realized in the production and application processes.

Methods and reports for presenting genetic information that is patient-specific and relevant to treatment of neuropsychiatric disorders, including treatment resistant psychiatric disorders, to aid in patient treatment in a phenotype, genotype or biomarker-specific manner. The methods and reports examine biomarkers for dysfunction of three axes relevant to treating neuropsychiatric disorders and provide interpretive comments to aid in treatment. Combining biomarker information from each of the three axes (the autonomic arousal axis, the emotional valence, attention, reward and executive brain function axis, and the long-term potentiation and long-term depression (LTP-LTD) function axis) provides an unexpectedly comprehensive and effective means for directing treatment of neuropsychiatric disorders, including particularly treatment resistant disorders (TRD).

The invention provides application of a sesquiterpene compound 6-OAP in preparation of STAT3 inhibitors and in treatment of diseases unusually relevant to STAT3, and a pharmaceutical composition for treatment of diseases unusually relevant to STAT3. The pharmaceutical composition contains 6-OAP. 6-OAP can quickly combine with STAT3, can significantly inhibit phosphorylation of STAT3 in a cell and animal tumor-bearing model and significantly inhibit the activity of STAT3 induced by inflammatory factors, and has no significant toxic and side effect on other normal tissues. With the advantages of proper dose, significant curative effect, definite action target, and low toxic and side effects, etc., the 6-OAP has wide anticancer and anti-inflammatory application prospects clinically.

The invention discloses a medicinal composition for treating chronic rhinitis. The medicinal composition mainly comprises the following components in parts by weight: 5 to 20 parts of gastrodia tuber, 25 to 35 parts of cocklebur fruit, 4 to 16 parts of mint, 5 to 20 parts of stiff silkworm, 4 to 16 parts of agastache rugosus, 4 to 16 parts of magnolia flower, 10 to 30 parts of Shuanggou, 2 to 10 parts of asarum sieboldi mig, 4 to 16 parts of periostracum cicada, 10 to 25 parts of pinellia ternate, 15 to 30 parts of radix angelicae, 12 to 25 parts of ligusticum sinense oliver, 5 to 15 parts of chrysanthemum, 5 to 15 parts of angelica, 1 to 5 parts of polygala root, 15 to 25 parts of Szechuan lovage rhizome, 12 to 25 parts of radix aucklandiae, 10 to 25 parts of Quinoa, 1 to 5 parts of pericarpium citri reticulatae and 10 to 25 parts of magnolia obavata. The medicinal composition can significantly enhance the phenomena of nasal cavity and nasopharynx mucous membrane hyperaemia, edema and the like, reduces purulent secretion, has the advantages of small toxic or side effect, low cost and the like, and can be widely used as a Chinese medicament for treating the chronic rhinitis.

The invention discloses a small probability event reproduction method and device, a storage medium and electronic equipment. The method comprises the steps of recording an operation process of reproducing a vulnerability event on first test equipment, and generating a test script, circularly executing the test script on at least one piece of second test equipment, and detecting whether a to-be-reproduced vulnerability event occurs in an execution result of the test script or not, and if so, acquiring log information of executing the test script by the second test equipment, and stopping executing the test script. The vulnerability can be automatically reproduced on multiple pieces of test equipment, for small-probability vulnerability events, reproduction operation does not need to be manually received, the labor cost is saved, meanwhile, the reproduction operation can be accurately restored on the basis of the test script, the difference caused by manual operation is reduced, and thereproduction rate of the vulnerability is increased.

The invention discloses a preparation method of modified sericite powder. The preparation method comprises the following steps: S1, adding lauryl polyoxyethylene ether, ethoxylated fatty acid methyl ester and sodium dodecylbenzene sulfonate into water; stirring and dissolving; carrying out ultrasonic de-foaming; then adding a silane coupling agent in sequence and stirring and dissolving to obtainan organic modified solution; S2, adding sericite powder into the organic modified solution and heating and stirring; vibrating and carrying out ultrasonic treatment; cooling to room temperature to obtain a sericite powder mixed solution; S3, centrifuging the sericite powder mixed solution at a high speed and removing supernatant; flatly laying sediment on a utensil and drying in vacuum to obtaina modified sericite dried cake; S4, grinding the modified sericite dried cake, carrying out the ultrasonic treatment, sieving and sub-packaging to obtain the modified sericite powder. The preparationmethod disclosed by the invention is simple to operate and high in recurrence rate; the prepared sericite powder has small granularity, large surface area, good wetting and dispersion effects and a wide application range.

The invention discloses a medicine membrane for treating dental ulcer, which comprises a matrix and the following Chinese medicinal herbs of: 15-25g of gallnut, 5-10g of indigo naturalis, 10-15g of rhizoma atractylodis, 10-15g of sinkiang arnebia root and 3-5g of pearl powder. The invention also discloses a preparation method of the medicine membrane. The medicine membrane overcomes the defects of short treatment time, short medicine attaching time and inconvenience for use of the traditional powder medicine, can be attached on an affected par, and has the advantages of rapidness of absorption, quick effect taking capacity, high medicine utilization rate and low recurrence rate. Meanwhile, the medicine membrane has the characteristics of no stimulation, good mouthfeel, rapidness of absorption, convenience and sanitation for medication and simple and convenient preparation process, is especially suitable for the hospital preparation and the industrialized production, and is an effective medicine which is worthy of being popularized and is used for treating the dental ulcer.

The invention provides a method for detecting thiol compounds in an oil product by use of an in-situ plated bismuth-film electrode and cyclic voltammetry. A small quantity of oil product containing thiol is added to an acetic acid-sodium acetate/methanol supporting electrolyte solution containing bismuth ions, and cyclic voltammetric detection is performed by use of a tri-electrode system. Due to strong interaction between the thiol and the bismuth ions, the cyclic voltammetric curve is enabled to have one more pair of oxidation and reduction peaks. Under optimized conditions, the intensity of the oxidation peaks and the reduction peaks is directly proportional to the concentration of the thiol, and therefore, the content of the thiol compounds in the oil product can be detected quantitatively. The method is characterized in that the oil product can be directly detected without pretreatment steps such as extraction, and the thiol compounds in samples can be selectively detected.

The invention relates to a traditional Chinese medicine preparation, and in particular relates to grass oil for treating arthritis and traumatic injury. The grass oil is prepared from the following traditional Chinese medicine raw materials: 50g of codonopsis pilosula, 40g of Chinese actinidia root, 40g of eucommia ulmoides, 15g of rhizoma cyperi preparata, 40g of fructus lycii, 15g of rhizoma corydalis, 50g of Chinese angelica, 35g of rhizoma ligustici chuanxiong, 40g of herba cistanche, 30g of rehmannia glutinosa, 30g of morinda officinalis, 30g of creeping oxalis, 12g of rhizoma coptidis, 20g of frankincense, 15g of radix astragali, 20g of myrrh, 20g of liquorice, 35g of radix achyranthis bidentatae, 45g of cortex acanthopanacis, 20g of safflower, 15g of aralia chinensis, 30g of radix salviae miltiorrhizae, 35g of radix aconiti preparata, 30g of herba lycopi, 35g of radix aconiti kusnezoffii preparata, 40g of herba asari, 40g of radix cynanchi paniculati, 30g of nidus vespae, 30g of rhizoma atractylodis macrocephalae, 25g of radix clematidis, 30g of fructus xanthii, 35g of folium artemisiae argyi, 30g of radix linderae leaves, 35g of argy wormwood leaf and 30g of red dates. The grass oil provided by the invention has a scientific formula and realizes an obvious curative effect on treating arthritis and traumatic injury.

The invention discloses an automobile fender material. The automobile fender material is prepared from waste tires, crude chloroprene rubber, polyethylene resin, molybdenum disulfide, sericite powder, oleic acid, silicon oil, a dispersing agent, 2-(2'-hydroxy-3'5'-ditert-phenyl)-5-benzotriazole chloride, 4-benzoyloxy-2,2,6,6-tetramethylpiperidine, an anti-aging agent and a vulcanizing agent. The preparation method includes steps of pretreatment of waste tires and polyethylene resin, plastication of crude chloroprene rubber, mixing of auxiliary agents, thermal forming of rubber materials, demoulding and twice vulcanization. The automobile fender material has advantages of extensive raw material sources, cheap raw materials, reasonable ratio, low production cost, excellent flexibility, impact resistance, abrasion resistance and aging resistance and less proneness to breakage, and a preparation process is simple, low in energy consumption and high in repetition rate.