162results about How to "Moderate dose" patented technology

The invention discloses an aloe-containing composition for controlling oil and removing acnes. The composition is prepared from the following components in percentage by weight: 80-98 percent of aloe vera extract, 0.01-3 percent of laminaria saccharina extract, 1-3 percent of hamamelis virginiana extract, 0.5-5 percent of purslane extract, 0.2-0.5 percent of allantoin and the balance of cosmetic matrix. The aloe-containing composition can be used for radically remarkably regulating skin grease secretion, well inhibiting epifolliculitis caused by microbes, accelerating quick growth of tissues and cells at an inflammatory part and promoting healing. According to the composition, the effects of durably controlling oil and removing acnes can be realized by utilizing natural herbal ingredients, safe and mild properties are far higher than those of current commercial products. Tests indicate that the capability for radically regulating skin grease secretion is higher than that of current commercial products, the effect and time for curing acnes are better than those of current commercial products, the grease secretion amount is greatly reduced, and the composition is durable and effective.

The invention discloses acne-removing aloe vera gel. The acne-removing aloe vera gel, 200 parts in total, is prepared from, by weight, 10-20 parts of sebum absorbing powder, 80-90 parts of fresh aloe vera juice, 2-10 parts of bee milk extract, 5-10 parts of plant flower extract, 4-10 parts of radix glycyrrhizae extract, 1-5 parts of sugar kelp extract, 5-10 parts of allantoin, 2-6 parts of carbomer, 10-15 parts of propylene glycol, 15-20 parts of glycerinum, 5-15 parts of triethanolamine and the balance deionized water. The acne-removing aloe vera gel can reduce sebum secretion and absorb skin sebum, has good effects on removing acnes, removing scars and promoting skin regeneration, and is remarkable in effect.

The invention relates to an application of a compound which has the following chemical structure or its pharmaceutically acceptable salt, solvate, hydrate, prodrug and its pharmaceutical composition in the preparation of medicines for preventing and treating cancer or other protein deacetylation related diseases.

The invention provides application of a sesquiterpene compound 6-OAP in preparation of STAT3 inhibitors and in treatment of diseases unusually relevant to STAT3, and a pharmaceutical composition for treatment of diseases unusually relevant to STAT3. The pharmaceutical composition contains 6-OAP. 6-OAP can quickly combine with STAT3, can significantly inhibit phosphorylation of STAT3 in a cell and animal tumor-bearing model and significantly inhibit the activity of STAT3 induced by inflammatory factors, and has no significant toxic and side effect on other normal tissues. With the advantages of proper dose, significant curative effect, definite action target, and low toxic and side effects, etc., the 6-OAP has wide anticancer and anti-inflammatory application prospects clinically.

The invention discloses a natural compound 6-O-angeloylplenolin (6-OAP) and application of medicinal composition thereof to the preparation of medicaments for treating multiple myeloma (MM) and lung cancer. The 6-O-angeloylplenolin and the medicinal composition thereof can activate a check point of a cell spindle, induce retardation and apoptosis of a mitotic phase, have obvious cytotoxicity in multiple myeloma and lung cancer cells and have effective anti-tumor proliferation effect in a nude mouse myeloma transplantation model. As a natural compound, the 6-OAP has the advantage of promoting cytotoxicity in the multiple myeloma and lung cancer cells by cooperating with routine medicaments, such as adriamycin, dexamethasone, bortezomib and the like. The 6-OAP shows ideal pharmacokinetic characteristics in an SD mouse and reaches a new level in the aspect of tumor target of natural compounds. The 6-OAP can provide a new treatment medicament to patients with MM and medicament resistant tumors and has the advantages of moderate dose and cost, convenience in administration, obvious treatment effect, low toxic and side effects and the like.

The invention discloses application of ethoxysanguinarine to preparation of a medicament for treating virus diseases of animals, in particular to application of the ethoxysanguinarine to preparation of medicaments for treating porcine reproductive and respiratory syndrome virus infection and porcine reproductive and respiratory syndrome, preparation of a virus gene expression inhibitor as well aspreparation of medicaments of antiviral drugs and medicaments for inhibiting porcine reproductive and respiratory syndrome virus. The ethoxysanguinarine has the functions of remarkably lowering nuclear protein gene expression of the porcine reproductive and respiratory syndrome virus and inhibiting viral multiplication; and in vitro cell pharmacological experiment shows that the ethoxysanguinarine has definite anti-virus effect. The ethoxysanguinarine has wide application prospect in treatment and control of porcine reproductive and respiratory syndrome virus infection. The monomer has an easily-obtained source, low cost and higher market value.

The invention relates to a formula and a preparation method of a Hui nationality traditional Chinese medicinal Radix Astragali and Sonchus oleraceus L. root stomach cancer treatment pill. The pill is a green high-tech Chinese herbal medicine used for treating late stomach cancer, especially late stomach cancer which cannot be operated due to various reasons. The pill is a traditional Chinese medicinal pill prepared through the following steps: mixing of Radix Astragali, Radix Codonopsis, Sonchus oleraceus L. root, Cortex Acanthopanacis, Malaytea Scurfpea Fruit, Polygonatum sibiricum and other Chinese herbal medicines in proportion, water adding, decoction, extraction, concentration and pill preparation. The pill is mainly used for treating the stomach cancer, and also is used for treating the throat cancer, the esophagus cancer, the cardiac cancer, the colorectal cancer and other digestive system cancers. The pill has the characteristics of small medicine variety quantity and moderate dosage, and all the medicines are proved by modern medical science pharmacological experiments to be suitable for treating the cancers.

The invention relates to a formula and a preparation method of a Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid. According to the present invention, the Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid is the green high-tech Chinese herb for esophageal cancer treatment; and hedyotis diffusa willd, scutellaria barbata, panax notoginseng and other Chinese herbs are mixed according to a certain ratio, water is added, and decoction, extraction and concentration are performed to obtain the traditional Chinese medicine oral liquid; and the Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid mainly treats esophageal cancer, can further treat throat cancer, stomach cancer, large intestine cancer and other digestive system cancers, and has characteristics of moderate components and moderate doses, wherein the modern medical pharmacology experiment results prove that the selected medicines can treat cancers, and the body functions are fundamentally improved and the cell cancerization is prevented in the low cost manner so as to recover the health body.

The invention concretely relates to a formula and a preparation method of a Hui Nationality traditional Chinese medicinal scorpion breast cancer treatment granule. The granule is a green high-tech Chinese herbal medicine used for treating the breast cancer. The granule is a traditional Chinese medicinal granule prepared through the following steps: mixing of scorpions, Chinese gall, Herba Taraxaci and other Chinese herbal medicines according to a certain ratio, water adding, decoction, extraction, concentration and granulation. The granule is mainly used for treating the breast cancer, and also is used for treating pancreas cancer, liver cancer, lung cancer, cervical cancer, gastrointestinal cancer and skin cancer. The granule has the characteristics of suitable medicine variety quantity and moderate dosage, and all the medicines are proved by modern medical science pharmacological experiments to be suitable for treating the cancers. The granule fundamentally improves the body functions and prevents condition exacerbation at a low cost in order to recover the health of bodies.

The invention provides a formula and preparation method of Hui-nationality traditional Chinese medicine aralia root bark granules for treating gastric cancer. The medicine is a green and high-tech traditional Chinese medicine for treating advanced gastric cancer, especially the advanced gastric cancer which cannot be subjected to a surgery due to various reasons. The Hui-nationality traditional Chinese medicine aralia root bark granules are traditional Chinese medicine granules prepared by mixing traditional Chinese medicines including aralia root bark, rhizoma curcumae, herba sarcandrae, fiveleaf akebia fruit, seaweed, cortex ailanthi, aloe and the like at a certain ratio, adding water and decocting, extracting, concentrating and granulating. The Hui-nationality traditional Chinese medicine aralia root bark granules are used for mainly treating the gastric cancer and can also be used for treating digestive system cancers including pharyngolaryngeal cancer, esophageal cancer, cardiac cancer, colorectal cancer and the like. The Hui-nationality traditional Chinese medicine aralia root bark granules have the characteristics of a few of medicines and moderate dosage; modern medicine pharmacological experiments of most of the selected medicines show that the medicines can be used for treating the cancer.

The invention provides a technique for realizing precisely fixed-point RNA shearing in fish embryos. A CasRx-mediated RNA editing technique is used, only mRNA of CasRx and specific targeted guidance RNA need to be provided, precisely fixed-point RNA knockdown can be realized in the fish embryos, and the technique has the advantages such as high efficiency, high specificity, convenience and low cost. The problems of faced low efficiency of a current existing siRNA technique and high cost and prone off-target of a Morpholino-technique-mediated gene knockout technique are solved.

The invention relates to the field of electronic technologies, and discloses a key mounting structure and method, a key assembly and an electronic device. In the implementation mode of the invention, the key mounting structure comprises a keycap, a keycap fixing member and a shell; the shell is provided with an opening corresponding to the keycap; the keycap fixing member is fixed at the inner wall of the shell; the keycap is mounted from the outer side of the shell to the inner side of the shell through the opening, and the keycap is fixed at a first surface of the keycap fixing member, wherein the area of the first surface of the keycap fixing member is greater than the bottom area of the keycap. By adopting the implementation mode of the invention, the overall strength of the electronic device is enabled to be high, the thickness can be reduced, and a problem of electrostatic discharge is solved.

The invention relates to a formula of Hui nationality traditional Chinese medicine astragalus membranaceus root stomach cancer-dispersing granules and a preparation method thereof. The granules are Chinese herbal medicine with environmental friendlessness as well as high science and technology for treating stomach cancer, especially stomach cancer with difficult operation at a late period due to various reasons; the Hui nationality traditional Chinese medicine astragalus membranaceus root stomach cancer-dispersing granules comprise the raw materials of astragalus membranaceus, radix Codonopsis, bitter herbs root, cortex acanthopanacis, Psoralea corylifolia and polygonatum rhizome according to a certain proportion, and the preparation method comprises the steps of mixing, adding water, decocting, extracting, concentrating, and granulating; and the astragalus membranaceus root stomach cancer-dispersing granules are used for mainly treating digestive system cancers such as stomach cancer, throat cancer, esophagus cancer, cardia cancer, and colorectal cancer. The astragalus membranaceus root stomach cancer-dispersing granules have the characteristics of moderate flavor and dosage, and the selected raw materials can be used for treating cancer through modern medical pharmacology experiments.

The invention relates to Hui nationality traditional Chinese medicine Chinese caterpillar fungus pills for treating lung cancer and a preparation method thereof. The traditional Chinese medicine Chinese caterpillar fungus pills for treating lung cancer are a Chinese herbal medicine product having advantages of environmental protection as well as high science and technology, which take Cordyceps sinensis, Chinese aralia, oyster, laminaria japonica, Herba Pteridis multifidae and Salvia chinensis according to a certain proportion, the above Chinese herbal medicines are mixed, water is added in a mixture, the mixture is decocted, extracted, concentrated, and pelleted to obtain the product. The traditional Chinese medicine Chinese caterpillar fungus pills are mainly used for treating lung cancer, and treating digestive system cancers such as pharyngolaryngeal cancer, stomach cancer and colorectal cancer, and have the characteristics of moderate flavor and dosage, the selected Chinese herbal medicines are proved for treating cancer by modern medical pharmacological experiments, with low cost, the body function can be fundamentally improved, condition deterioration is prevented, and body health is recovered.

The invention discloses an immunohistochemical immune enzyme labeling method, which mainly comprises the following steps of paraffin sectioning, xylene dewaxing, gradient alcohol dehydration, blocking, antigen repairing, sealing, primary antibody adding, secondary antibody adding, SP adding, developing, restaining and the like. The immunohistochemical immune enzyme labeling method is simple to operate, the color can be accurately controlled through microscopic examination, over-dyeing is avoided, and the dyeing effect is ensured. The preparation method of each solution is simple, the dosage is proper, the use is convenient, and waste is avoided. The invention further discloses a kit for the immune enzyme labeling method. The kit comprises an endogenous peroxidase blocking agent, a high-efficiency confining liquid, biotin-labeled goat anti-mouse IgG and streptomycete avidin-peroxidase. The kit comprises the solvents required by the immune enzyme labeling method, and each solvent is packaged by dropping bottles, so that the kit is convenient to use.

The invention discloses garter snake medical wine and a preparation method thereof, and belongs to the technical field of snake wine processing. The garter snake medical wine is mainly prepared from garter snakes, tuber fleeceflower roots, turmeric rhizome, sappan caesalpinia wood, mongolian milkvetch roots, dwarf lilyturf roots, English walnut seeds, tendrilleaf fritillary bulb, wild mint herb, fixweed transymustard seeds, eucommia bark, dasystyle honeysuckle immature flowers, trilobedleaf kudzuvine roots, Himalayan teasel roots, Chinese angelica roots, indigo-colored woad leaves, veitch peony roots, yanhusuo rhizome, nut-vomitive poisonnut seeds, subshrubby peony roots-barks, common papermulberry fruits, Japanese fleecceflower rhizome, barbary wolfberry fruits, fresh ginger, baron's drynaria rhizome, rock candy and Baijiu. The garter snake medical wine has the functions of clearing and activating channels and collaterals, moistening lung and relieving cough, remarkable effects on treatment of rheumatic arthritis, low back and leg pain, cough and excessive phlegm and has the advantages of simple preparation method, low cost, convenience in taking and no toxic and side effects.

The invention provides a recombinant oncolytic adenovirus and application thereof, the recombinant oncolytic adenovirus is constructed based on a type-5 adenovirus, the genome of the recombinant oncolytic adenovirus comprises a nucleotide sequence for coding a BiTE antibody or an antibody fragment, and the nucleotide sequence for coding the BiTE antibody or the antibody fragment is located between a virus element mCMV and a virus element MCS-3Flag. According to the recombinant oncolytic adenovirus, the targeting of T cells to tumor cells is improved, adverse reactions caused by systemic administration of BiTE are avoided, and the killing effect of the oncolytic adenovirus on solid tumors is improved through the activation effect of BiTE on an immune microenvironment.

The invention discloses a oil control acne removal composition, which is characterized by being mainly prepared from the following ingredients in parts by weight: 5 to 10 parts of herba sedi, 4 to 9 parts of centaurea cyanus flowers, 4 to 9 parts of mung bean sprouts, 3 to 8 parts of herba houttuyniae and 3 to 6 parts of cordierite lotus. The composition uses natural plant ingredients to achieve the continuous oil control and acne removal effects; the safety performance and the mild performance are good. Experiment results show that the capability of the natural oil control acne removal composition for fundamentally regulating the skin grease secretion is good; the grease secretion quantity is greatly reduced; the action is durable and effective; in addition, the recipe is scientific; thedose is proper; the manufacturing price is low; the curative effect is fast and obvious.

The invention provides a formula and preparation method of Hui-nationality traditional Chinese medicine toad pills for treating breast cancer. The medicine is a green and high-tech traditional Chinese medicine for treating the breast cancer. The Hui-nationality traditional Chinese medicine toad pills are traditional Chinese medicine pills prepared by mixing traditional Chinese medicines including toad, radix pseudostellariae, rhizoma belamcanda and the like at a certain ratio, adding water and decocting, extracting, concentrating and pilling. The Hui-nationality traditional Chinese medicine toad pills are used for mainly treating the breast cancer and can also be used for treating pancreatic cancer, liver cancer, lung cancer, cervical cancer, gastrointestinal cancer, skin cancer and the like. The Hui-nationality traditional Chinese medicine toad pills have the characteristics of a few of medicines and moderate dosage; modern medicine pharmacological experiments of most of the selected medicines show that the medicines can be used for treating the cancer; the physical function is radically improved by relatively low cost; cell cancerization is prevented so that the body health is recovered.

The invention provides a formula and preparation method of Hui-nationality traditional Chinese medicine rhizoma curcumae pills for treating gastric cancer. The medicine is a green and high-tech traditional Chinese medicine for treating advanced gastric cancer, especially the advanced gastric cancer which cannot be operated on due to various reasons. The Hui-nationality traditional Chinese medicine rhizoma curcumae pills are traditional Chinese medicine pills prepared by mixing traditional Chinese medicines including rhizoma curcumae, fiveleaf gynostemma herb, herba sarcandrae, radix linderae, herba pteridis multifidae, Chinese lobelia herb and the like at a certain ratio, adding water and decocting, extracting, concentrating and pilling. The Hui-nationality traditional Chinese medicine rhizoma curcumae pills are used for mainly treating the gastric cancer and can also be used for treating digestive system cancers including pharyngolaryngeal cancer, esophageal cancer, cardiac cancer, colorectal cancer and the like; the Hui-nationality traditional Chinese medicine rhizoma curcumae pills have the characteristics of a few of medicines and moderate dosage; modern medicine pharmacological experiments of most of the selected medicines show that the medicines can be used for treating the cancer.