True three-dimensional highly integrated temperature-controlled microreactor and its processing method
A highly integrated, microreactor technology, applied in chemical instruments and methods, bioreactor/fermenter combinations, bioreactors/fermenters for specific purposes, etc., to achieve uniform temperature distribution, save reaction time, and improve reaction The effect of efficiency and success rate
Active Publication Date: 2021-02-26
XI AN JIAOTONG UNIV
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Problems solved by technology
[0007] The purpose of the present invention is to solve the existing problems in the preparation method, device structure and temperature control mode of the existing temperature-controlled microreactor, and propose a true three-dimensional high-integration temperature-controlled microreactor and its processing method
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[0040] The present invention is described in detail below in conjunction with accompanying drawing and specific embodiment:
[0041] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. The following embodiments are used to illustrate the present invention , but not to limit the scope of the present invention.
[0042] see figure 2 , Figure 5 , Figure 6 and Figure 7 A true three-dimensional highly integrated temperature-controlled microreactor comprises a glass chip 1 and a reaction unit and a heating unit integrated in the glass chip 1, and the glass chip 1 is a quartz glass chip. The reaction unit is a micro-straight channel 2 arranged in the glass chip, and the heating unit is a helical metal micro-coil 3 surrounding the periphery of ...
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The invention belongs to the technical field of optical micromachining, and specifically relates to a true three-dimensional high-integration temperature-controlled microreactor and a processing method thereof. question. The present invention adopts femtosecond laser wet etching combined with metal micro-solidification technology to produce a true three-dimensional high-integration temperature-controlled micro-reactor, including a micro-straight channel arranged in a glass chip and a spiral metal micro-coil surrounding the straight channel. . The reaction unit and heating unit of the temperature-controlled microreactor are integrated into a glass chip, which greatly improves the integration; and because the heating unit is surrounded by the periphery of the reaction unit, the temperature distribution in the microreactor is more uniform, saving reaction time, The reaction efficiency and success rate are improved; the temperature control of the fluid in the microreactor is realized by controlling the magnitude of the energized current at both ends of the microcoil, and the temperature control method is simple.
Description
technical field [0001] The invention belongs to the technical field of optical micromachining, and in particular relates to a true three-dimensional highly integrated temperature-controlled microreactor and a processing method thereof. Background technique [0002] In recent years, with the development of micro-nano manufacturing technology, the miniaturization of equipment has become an important development direction. The microfluidic chip, as a chemical or biological laboratory built on a chip with an area of several square centimeters, is used to operate and transmit fluids in the order of microliters to nanoliters, and has the potential to miniaturize and integrate biochemical analysis equipment. The functions of automation, automation and portability will have broad application prospects in the future development of equipment miniaturization. [0003] The microreactor manufactured by micromachining technology has a micron-scale reaction space. The reduction in size...
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IPC IPC(8): C12M1/00C12M1/38
CPCB01L3/502707B01L7/52B01L2300/1805C12M23/16C12M41/22
Inventor 陈烽郑书浩杨青山超
Owner XI AN JIAOTONG UNIV