Application of medicinal composition in preparation of medicine for treating pneumonia

A composition and drug technology, applied in the direction of drug combination, medical raw materials derived from gymnosperms, antibacterial drugs, etc., can solve the problems of reduced therapeutic effect, abuse, increased drug resistance, etc., to shorten the time of antipyretic, Reduce adverse reactions and relieve pain

Inactive Publication Date: 2018-12-21
临沂高新区金迪科技信息服务中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the pathogenesis of mycoplasma pneumonia is related to both direct toxic effects and immune damage, the application of macrolides is prone to incomplete treatment and inability to completely remove the pathogen, resulting in easy recurrence of the disease
In recent years, with the increase in the incidence of mycoplasma infection and the abuse of antibiotics, the drug resistance of the human body has increased, resulting in a continuous decrease in the therapeutic effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The preparation of embodiment 1 Chinese medicine granule

[0023] Weigh and clean 32 parts of Houttuynia cordata, 32 parts of Shegan, 25 parts of Arborvitae leaves, 20 parts of Scutellaria baicalensis, 25 parts of duckweed, 25 parts of tangerine peel, 12 parts of ephedra and 12 parts of paeonol, combine them, add water and decoct twice , add water for the first time to 10 times the weight of the medicinal material, decoct for 1.5h, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70℃ To the extract with a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand for 24 hours, filter, and the filtrate is at 0.07MPa, 65°C Concentrate under reduced pressure under certain conditions to a relative density of 1.25 at 65°C, and recover ethanol to obtain a concentrated solution, which is then spray-dri...

Embodiment 2

[0024] The preparation of embodiment 2 Chinese medicine granules

[0025] Weigh and clean 40 parts of Houttuynia cordata, 27 parts of Shegan, 20 parts of Arborvitae leaves, 25 parts of Scutellaria baicalensis, 29 parts of duckweed, 18 parts of tangerine peel, 10 parts of ephedra and 15 parts of paeonol, combine them, add water and decoct twice , add water for the first time to 10 times the weight of the medicinal material, decoct for 1.5h, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70℃ To the extract with a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand for 24 hours, filter, and the filtrate is at 0.07MPa, 65°C Concentrate under reduced pressure under certain conditions to a relative density of 1.25 at 65°C, and recover ethanol to obtain a concentrated solution, which is then spray-dr...

Embodiment 3

[0026] The preparation of embodiment 3 Chinese medicine granules

[0027]Weigh and clean 26 parts of Houttuynia cordata, 26 parts of Shegan, 30 parts of oriental cypress leaves, 18 parts of scutellaria baicalensis, 20 parts of duckweed, 30 parts of tangerine peel, 16 parts of ephedra and 8 parts of paeonol, combine them, add water and decoct twice , add water for the first time to 10 times the weight of the medicinal material, decoct for 1.5h, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70℃ To the extract with a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand for 24 hours, filter, and the filtrate is at 0.07MPa, 65°C Concentrate under reduced pressure under certain conditions to a relative density of 1.25 at 65°C, and recover ethanol to obtain a concentrated solution, which is then spra...

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PUM

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Abstract

The invention relates to application of a medicinal composition in preparation of a medicine for treating pneumonia. The composition is prepared from the following traditional Chinese medicine materials in parts by weight: 26-40 parts of herba houttuyniae, 26-40 parts of rhizoma belamcandae, 18-30 parts of cacumen biotae, 15-25 parts of radix scutellariae, 18-30 parts of common ducksmeat herb, 18-30 parts of dried tangerine peel, 8-16 parts of herba ephedrae and 8-16 parts of cortex moutan. The medicinal composition can be used in match with erythrocin to treat mycoplasma pneumonia in childrenand is capable of effectively reducing the time of abatement of fever, the cough eliminating time, and the lung noise eliminating time of the children, and thus the pain of children patients can be relieved.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating mycoplasma pneumonia, in particular to a traditional Chinese medicine composition for treating children with mycoplasma pneumonia and its application, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Mycoplasma pneumoniae is the causative agent of mycoplasma pneumonia in children. It is a "pleuropneumonia-like microorganism" between bacteria and viruses. After infection, it will cause multi-system immune damage. Impairment of the body's immune function will lead to other concurrent infections and mycoplasma pneumoniae pneumonia recurrent and persistent, severe mycoplasma pneumonia can lead to death in children. In the past, traditional treatment methods preferred macrolide antibiotics, especially azithromycin, because of its strong tissue penetration, high concentration in lung tissue, and ability to penetrate into cells to effectively kill...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/16A61P11/00A61P31/04
CPCA61K36/78A61K9/1652A61K36/14A61K36/17A61K36/539A61K36/65A61K36/71A61K36/752A61K36/88A61P11/00A61P31/04A61K2300/00
Inventor 吴兴玉
Owner 临沂高新区金迪科技信息服务中心
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