The invention provides a traditional Chinese medicine tablet for treating Mycoplasma gallisepticum infection and a preparation method of the traditional Chinese medicine tablet, and belongs to the technical field of veterinary medicine. According to the traditional Chinese medicine tablet for treating the Mycoplasma gallisepticum infection and the preparation method of the traditional Chinese medicine tablet, drugs with heat clearing, toxicity removing, and infectious disease treating effects such as radix isatidis and flos lonicerae are used as main drugs, radix scutellariae has broad-spectrum antibacterial and antiviral effects, prevents secondary or concurrent bacterial infections, and is a ministerial drug in a prescription, radix glycyrrhizae has spleen tonifying, qi benefiting, lungmoistening, cough relieving, heat clearing, detoxifying, and medical nature regulating functions, aster has lung moistening, qi descending, inflammation diminishing, and cough relieving functions, andthe radix glycyrrhizae and the aster are both supplementary drugs; and the various drugs are jointly used for realizing heat clearing, detoxifying, cough relieving, and asthma relieving effects together. According to the traditional Chinese medicine tablet, the effects on preventing and treating the Mycoplasma gallisepticum infection are good, imbalance of various aspects in the course of a disease can be improved and regulated, coordination of an internal environment and recovery of the disease are promoted, the multi-directional, multi-level, multi-target pharmacological characteristics ofa compound traditional Chinese medicine are given full play to, and the characteristics that residues are low, toxicity is low, the curing rate is high, and drug resistance is not prone to being generated are realized.