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Vacuum pulse hydrogen peroxide sterilization device for medicinal aluminum tube sterilization

A hydrogen peroxide and vacuum pulsation technology, applied in water supply devices, sanitary equipment for toilets, chemistry, etc., can solve the problems of affecting the quality of aluminum pipes, inconvenient process control, and bacterial contamination of aluminum pipes, and shorten the sterilization cycle. , the effect of avoiding damage

Pending Publication Date: 2019-01-04
湖北科益药业股份有限公司
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AI Technical Summary

Problems solved by technology

However, bromine oxygen sterilization cannot reach the sterility standard due to its poor penetrating power; although radiation sterilization has a good sterilization effect, it has an impact on the quality of aluminum tubes, and radiation sterilization is generally entrusted to a third party to complete. It is convenient for process control, and the aluminum tube may also be contaminated during transportation and storage after sterilization
The sterilization effect of vaporized hydrogen peroxide (VHP) is good, but the liquid hydrogen peroxide is corrosive to the aluminum tube after contacting it

Method used

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  • Vacuum pulse hydrogen peroxide sterilization device for medicinal aluminum tube sterilization
  • Vacuum pulse hydrogen peroxide sterilization device for medicinal aluminum tube sterilization

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Embodiment Construction

[0022] Below, the applicant further describes the technical solution of the present invention in detail in conjunction with specific examples, so that those skilled in the art can better understand the present invention and implement it, but the examples given are not intended to limit the scope of protection claimed by the present invention.

[0023] The invention provides a vacuum pulse hydrogen peroxide sterilizing device for sterilizing medicinal aluminum tubes, such as figure 1 As shown, it includes a cabinet body 1 and a cabinet door 32. The cabinet body 1 is provided with a sterilization chamber 2 for placing aluminum tubes to be sterilized, a computer control system for intelligently monitoring the sterilization state and controlling the sterilization process ( Not shown in the figure), control display interface 31, viewing mirror observation window 33; a heating jacket 3 is arranged outside the sterilization chamber 2, and an electric heating wire 4 is arranged inside ...

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Abstract

The invention relates to a vacuum pulse hydrogen peroxide sterilization device for medicinal aluminum tube sterilization. The device comprises a cabinet body, wherein a sterilization cavity and a computer control system are arranged on the cabinet body; a heating jacket is arranged outside the sterilization cavity; the heating jacket is internally provided with electric heating wires; the sterilization cavity is connected with a drying unit, a vacuuming unit, a sterilization unit and a residue discharge unit respectively; the vacuuming unit comprises a vacuuming device, a first valve, a secondvalve, a third valve, a hydrogen peroxide concentration sensor and a drying catalyst storage tank; the first valve, the vacuuming device and the third valve are sequentially communicated through a main vacuuming pipeline; a gas recycling pipeline is arranged between the vacuuming device and the third valve; the second valve, the hydrogen peroxide concentration sensor and the drying catalyst storage tank are sequentially communicated through a gas recycling pipeline. By adopting the device, a vacuuming technique is sufficiently utilized, gasified hydrogen peroxide is conveyed into different parts of inner and outer surfaces of a bottle in a vacuum chamber, and sterilization dead angles can be avoided; by adopting the device, aluminum tube surface damage can be also avoided in the sterilization process.

Description

technical field [0001] The invention relates to the technical field of sterilization for pharmaceutical production, in particular to a vacuum pulse hydrogen peroxide sterilizing device for sterilizing medicinal aluminum tubes. Background technique [0002] According to the 2010 version of GMP requirements, all ophthalmic preparations must pass the GMP certification inspection as sterile preparations by the end of 2015. For example, the commonly used ophthalmic preparation ganciclovir ophthalmic gel, because it cannot be produced by terminal sterilization process, in order to ensure that the finished product reaches the sterile quality standard, it is necessary to ensure that the gel before filling reaches the sterile standard and the filling When the pharmaceutical aluminum tube meets the sterility requirements. [0003] However, domestic aluminum tube manufacturers are still unable to supply pharmaceutical aluminum tubes that meet sterile standards, and aluminum tubes may ...

Claims

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Application Information

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IPC IPC(8): A61L2/20A61L2/24A61L2/26A61L101/22
CPCA61L2/208A61L2/24A61L2/26A61L2202/23A61L2202/14
Inventor 刘毅贾徵刘敏方征远
Owner 湖北科益药业股份有限公司
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