PPG monitoring system based on multi-layer time-delay neural network for removing motion artifacts

A motion artifact, neural network technology, applied in diagnostic recording/measurement, medical science, sensors, etc., can solve problems such as difficult practical application, limited effect, strong and weak reference signal correlation, and achieve improved artifact removal effect, Accurate Artifact Removal

Active Publication Date: 2019-01-18
FUDAN UNIV
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  • Abstract
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AI Technical Summary

Problems solved by technology

However, no matter which method is used, it faces problems and challenges such as the strength of the reference signal correlation, the time delay between the reference signal and the noisy PPG signal, the trade-off between the number of filter taps and the sampling rate, etc., and the effect is limited in practical applications.
[0007] In addition, methods based on classical wavelet transform [12,13] and dual-tree complex wavelet transform [14,15] have also been proposed and proved to be suitable for certain motion situations, but the methods based on this are different for different Devices and various PPG waveforms collected for different experimental objects may need to change different threshold selection strategies, which is not conducive to the promotion among smart devices
[0008] In recent years, some researchers have also proposed based on time domain or frequency domain ICA [10,16-18], SSA [19,20], cycle-by-cycle Fourier series [21], empirical mode decomposition [22], Kalman filter [23], Wigner-Ville distribution [24] and other methods to remove artifacts, but these methods are either difficult to apply in practice [21], or are only proven to be effective under specific experimental conditions
In fact, there is still no universal and robust solution to this problem

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  • PPG monitoring system based on multi-layer time-delay neural network for removing motion artifacts
  • PPG monitoring system based on multi-layer time-delay neural network for removing motion artifacts
  • PPG monitoring system based on multi-layer time-delay neural network for removing motion artifacts

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Embodiment 1

[0065] 1. System framework

[0066] As an embodiment of the present invention, a complete electronic system including a wearable embedded system and a host computer terminal is designed, and its main structure is as follows figure 1 shown.

[0067] The PPG probe is designed as a small PCB that integrates a highly integrated dual-wavelength PPG sensor and a nine-axis inertial measurement unit (IMU). The PPG and motion data are transmitted to the main control board through the flexible printed circuit connection (FPC) and the I2C bus protocol running on it.

[0068] The main control board is responsible for receiving PPG and exercise sampling data, performing necessary processing on it (such as denoising), and extracting physiological parameters of interest (heart rate, blood oxygen saturation, etc.), and sending these sampling raw data and physiological parameters through Bluetooth 4.0 low-power wireless transmission and USB 2.0 high-speed wired transmission to upload to the...

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Abstract

The invention belongs to the technical field of medical equipment, in particular to a PPG monitoring system based on a multi-layer time-delay neural network for removing motion artifacts. The invention comprises a PPG probe, a transmission control motherboard and a PC host computer. PPG probe, transmission control motherboard forms wearable structure; The PPG probe comprises a PPG sensor and an IMU sensor, a front fixed PPG sensor and an LDO of the PCB, an IMU sensor and a FPC line connector are arranged on the back; The interrupt prompt lines of PPG sensor and IMU sensor are connected to GPIOrespectively. The transmission control motherboard is connected with the PPG probe through the FPC line, and the transmission control motherboard is connected with the PC host computer. The transmission control motherboard comprises a main control board and a wireless data transmission module. The main control board includes a motion artifact removing module of the multi-layer time delay network.The system can achieve real-time, on-line, accurate removal of PPG motion artifacts under intense exercise.

Description

technical field [0001] The invention belongs to the technical field of medical equipment, and in particular relates to a PPG monitoring system for removing motion artifacts based on a multi-layer time-delay neural network. Background technique [0002] In recent years, transmissive and reflective pulse oximetry devices based on photoplethysmography (PPG) have been greatly promoted and developed in the health and medical industries because of their portability, cheapness and accuracy, and are widely used in Vital signs monitoring, wearable devices and other fields. [0003] The detection of PPG signal is usually achieved by injecting light of one or more different wavelengths from the body surface into the subcutaneous vascular network, and recording the intensity of transmitted or reflected light. Oxygenated hemoglobin and unoxygenated hemoglobin in blood have differences in light absorption of different wavelengths, the steady-state and fluctuating parts of the PPG signal ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/1455A61B5/00
CPCA61B5/14551A61B5/7207A61B5/7246A61B5/7267
Inventor 徐珂陈炜姜新雨
Owner FUDAN UNIV
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