Intelligent hydrogel for preventing and treating cervical diseases and preparation method thereof

A hydrogel, intelligent technology, applied in sexual diseases, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. and other problems to achieve the effect of avoiding tissue contact with each other, promoting capillary constriction, and good adhesion performance.

Inactive Publication Date: 2019-01-18
杭州金花医药生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many shortcomings in the characteristics of these dosage forms themselves, such as the problem that liquids and gels are not easy to fix the wound surface. Although liquid preparations can be fully covered when washing, they have the shortcoming of short acting time, so that ideal treatment and prevention cannot be achieved. As a result, gel products are in a gel state when in contact with the wound, so it is difficul

Method used

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  • Intelligent hydrogel for preventing and treating cervical diseases and preparation method thereof
  • Intelligent hydrogel for preventing and treating cervical diseases and preparation method thereof
  • Intelligent hydrogel for preventing and treating cervical diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0045] Example 1

[0046] For the smart hydrogel of this embodiment, the raw material composition is shown in Table 1.

[0047] Table 1

[0048] Component name

[0049] The preparation method includes the following steps:

[0050] S1: Weigh the above weight of raw materials as shown in Table 1;

[0051] S2: Disperse and swell poloxamer 407 and poloxamer 188 at 0°C to obtain component a;

[0052] Mix hyaluronic acid, polyglutamic acid and yeast β-1,3-D-glucan and swell to obtain component b;

[0053] The water-soluble α-bisabolol, turmeric oil, borneol, and anthocyanins are made into an aqueous solution through a solubilization technique to obtain component c;

[0054] After cold soaking Sophora flavescens, cork, dandelion, fig leaves, and Cnidium for 1 hour in purified water, decocting for 2 hours and filtering to obtain primary filtrate and primary filter residue. Once the filter residue is re-decocted with purified water for 2 hours and filtered to obtain The secondary filtrate and t...

Example Embodiment

[0057] Example 2

[0058] For the intelligent hydrogel of this embodiment, the raw material composition is shown in Table 2.

[0059] Table 2

[0060]

[0061]

[0062] Refer to Example 1 for the preparation method.

Example Embodiment

[0063] Example 3

[0064] For the smart hydrogel of this embodiment, the raw material composition is shown in Table 3.

[0065] table 3

[0066] Component name

[0067] Refer to Example 1 for the preparation method.

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Abstract

The invention relates to the field of traditional Chinese medicine preparation, discloses an intelligent hydrogel for preventing and treating cervical diseases, and also discloses a preparation methodthereof. The intelligent hydrogel is prepared from block copolymer of polyoxyethylene polyoxypropylene ether, polyglutamic acid, hyaluronic acid, yeast dextran, glycyrrhizin organic polymer, compoundzedoary turmeric oil, fructus cnidii, radix sophorae flavescentis, water-soluble alpha-bisabolol, phellodendron, borneol, dandelion, anthocyanidin and so on. In a fluid state when injected into the body, After entering the body, it quickly distributes to the surface of the cervix and the bottom of the vagina, effectively covers the wound surface, and then the hydrogel is heat exchanged with the human body in the body to form a stable gel, and a gel layer with a spatial network structure is formed on the surface of the whole cervix and the bottom of the vagina, so that the drug ingredients inthe hydrogel can play a lasting role. The hydrogel can promote the convergence of cervical wound erosion surface, remove odor, reduce seepage fluid and blood, improve erosion, alleviate leucorrhea, and restore normal vaginal environment.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an intelligent hydrogel for preventing and treating cervical diseases, and also to a preparation method thereof. Background technique [0002] Cervical diseases, especially cervical erosion, acute and chronic cervicitis, etc. seriously affect women's health and are the main factors leading to cervical cancer. For the treatment of cervical diseases, there are many methods such as drug therapy, physical therapy, and surgical treatment. Among them, drug therapy is the perfection and supplement of other treatment methods and is indispensable in various treatments. [0003] The dosage forms of drug treatment basically include lotion, gel, solid powder and cervical cap, etc. These drug dosage forms play a key role in the treatment and prevention of cervical diseases. However, there are many shortcomings in the characteristics of these dosage forms the...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K47/10A61K36/9066A61P15/00A61P15/02A61K31/045A61K31/352
CPCA61K36/9066A61K47/10A61P15/00A61P15/02A61K9/0034A61K9/06A61K31/045A61K31/352A61K36/234A61K36/288A61K36/484A61K36/489A61K36/756
Inventor 宋天春
Owner 杭州金花医药生物科技有限公司
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