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A kind of antibacterial medical dressing for promoting wound healing and preparation method and application thereof

A wound healing and base material technology, which is applied in the field of medical materials, can solve the problems of poor stability of traditional Chinese medicine components and affect the effect of dressings, and achieve the effects of excellent effect, accelerated wound healing, and enhanced antibacterial effect

Active Publication Date: 2021-06-18
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The externally-used traditional Chinese medicine gel dressing is used to treat skin ulcers and bedsores. It is safe and effective, and can quickly promote the healing of skin ulcers and bedsore wounds. However, the stability of Chinese medicine components is poor, which affects the dressing effect.

Method used

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  • A kind of antibacterial medical dressing for promoting wound healing and preparation method and application thereof
  • A kind of antibacterial medical dressing for promoting wound healing and preparation method and application thereof
  • A kind of antibacterial medical dressing for promoting wound healing and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] A kind of medical dressing that antibacterial promotes wound healing, described medical dressing comprises reticular polyester fiber base material and hydrocolloid composition, and described hydrocolloid comprises by weight parts:

[0059]

[0060] The preparation method of described medical dressing is as follows:

[0061] (1) heating vaseline to 150°C to soften to obtain liquid vaseline;

[0062] (2) Add sodium carboxymethylcellulose and chitosan to the liquid vaseline obtained in step (1), mix and stir, heat to 140°C for melting, and vacuum defoam;

[0063] (3) coating the vacuum defoaming melt obtained in step (2) on a reticular polyester fiber substrate to obtain a substrate web;

[0064] (4) Porcine collagen polypeptide, A.SAP, epidermal growth factor and nano-calcium carbonate are prepared into bioactive microspheres with a particle size of 25 μm, and then the bioactive microspheres are sprayed on the substrate network described in step (3), Obtain antibacte...

Embodiment 2

[0067] A kind of medical dressing that antibacterial promotes wound healing, described medical dressing comprises reticular polyester fiber base material and hydrocolloid composition, and described hydrocolloid comprises by weight parts:

[0068]

[0069] The preparation method of described medical dressing is as follows:

[0070] (1) heating vaseline to 160°C to soften to obtain liquid vaseline;

[0071] (2) Add sodium carboxymethylcellulose and chitosan to the liquid vaseline obtained in step (1), mix and stir, heat to 150°C for melting, and vacuum defoam;

[0072] (3) coating the vacuum defoaming melt obtained in step (2) on a reticular polyester fiber substrate to obtain a substrate web;

[0073] (4) Porcine collagen polypeptide, A.SAP, epidermal growth factor and nano-calcium carbonate are prepared into bioactive microspheres with a particle size of 20 μm, and then the bioactive microspheres are sprayed on the substrate network described in step (3), Obtain antibacte...

Embodiment 3

[0076] A kind of medical dressing that antibacterial promotes wound healing, described medical dressing comprises reticular polyester fiber base material and hydrocolloid composition, and described hydrocolloid comprises by weight parts:

[0077]

[0078] The preparation method of described medical dressing is as follows:

[0079] (1) heating vaseline to 180°C to soften to obtain liquid vaseline;

[0080] (2) Add sodium carboxymethylcellulose and chitosan to the liquid vaseline obtained in step (1), mix and stir, heat to 160°C for melting, and vacuum defoam;

[0081] (3) coating the vacuum defoaming melt obtained in step (2) on a reticular polyester fiber substrate to obtain a substrate web;

[0082] (4) bovine collagen polypeptide, ε-polylysine, epidermal growth factor and calcium chloride are prepared into bioactive microspheres with a particle size of 30 μm, and then the bioactive microspheres are sprayed in step (3) The base material net is a medical dressing that is ...

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Abstract

The present invention provides an antibacterial and wound-healing medical dressing and its preparation method and application. The medical dressing comprises a reticulated polyester fiber base material and a hydrocolloid component, and the hydrocolloid comprises carboxymethyl fiber in parts by weight. 10-30 parts of plain sodium, 5-20 parts of chitosan, 5-15 parts of collagen polypeptide and 45-150 parts of petrolatum. The medical dressing of the invention has good moisturizing performance, can effectively absorb exudate and reduce the frequency of dressing replacement, has strong antibacterial performance, reduces the risk of wound infection, and significantly promotes wound healing.

Description

technical field [0001] The invention belongs to the field of medical materials, and relates to a medical dressing and its preparation method and application, in particular to an antibacterial and wound healing-promoting medical dressing, its preparation method and application. Background technique [0002] Antibacterial, hemostasis, and promotion of wound healing are often encountered problems in the medical field. Medical dressings are a type of medical material used for temporary coverage of various wounds and wound surfaces, which can avoid wound infection or other external factors, protect wounds, and promote wound healing. heal. Commercially available hemostatic dressings are generally simple dressings composed of ordinary non-woven fabrics and an adhesive layer. They mainly rely on absorbing wound blood and other exudates to achieve the purpose of hemostasis. If necessary, they must be treated or disinfected with drugs. Although conventional dressings such as gauze an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/32A61L15/26A61L15/20A61L15/46A61L15/44
CPCA61L15/20A61L15/26A61L15/28A61L15/325A61L15/44A61L15/46A61L2300/102A61L2300/104A61L2300/214A61L2300/404A61L2300/412A61L2300/414
Inventor 车七石刘少辉李新霞
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD